Entry
Symbol
ALK, CD246
Name
anaplastic lymphoma kinase [EC:
2.7.10.1 ]
Pathway
map05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
Disease
H00014 Non-small cell lung cancer
H01601 Anaplastic large-cell lymphoma
H01892 Peripheral T cell lymphoma
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
K05119 ALK, CD246; anaplastic lymphoma kinase
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
K05119 ALK, CD246; anaplastic lymphoma kinase
09162 Cancer: specific types
05223 Non-small cell lung cancer
K05119 ALK, CD246; anaplastic lymphoma kinase
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases
K05119 ALK, CD246; anaplastic lymphoma kinase
09183 Protein families: signaling and cellular processes
04090 CD molecules
K05119 ALK, CD246; anaplastic lymphoma kinase
Enzymes [BR:ko01000 ]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
K05119 ALK, CD246; anaplastic lymphoma kinase
Protein kinases [BR:ko01001 ]
Receptor tyrosine kinases (RTK)
ALK family
K05119 ALK, CD246; anaplastic lymphoma kinase
CD molecules [BR:ko04090 ]
Proteins
K05119 CD246, ALK; anaplastic lymphoma kinase (Ki-1)
BRITE hierarchy
Genes
» show all
Taxonomy UniProt
Reference
Authors
Morris SW, Naeve C, Mathew P, James PL, Kirstein MN, Cui X, Witte DP
Title
ALK, the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase (LTK)
Journal
Sequence
Reference
Authors
Palmer RH, Vernersson E, Grabbe C, Hallberg B
Title
Anaplastic lymphoma kinase: signalling in development and disease.
Journal
LinkDB
All DBs