Pongo abelii (Sumatran orangutan): 100172513 Help Entry 100172513         CDS       T01416                                  Symbol SPHK2 Name (RefSeq) sphingosine kinase 2   KO K04718   sphingosine kinase [EC:2.7.1.91] Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon00600   Sphingolipid metabolism pon01100   Metabolic pathways pon04020   Calcium signaling pathway pon04071   Sphingolipid signaling pathway pon04072   Phospholipase D signaling pathway pon04148   Efferocytosis pon04370   VEGF signaling pathway pon04371   Apelin signaling pathway pon04666   Fc gamma R-mediated phagocytosis pon05152   Tuberculosis Module pon_M00100   Sphingosine degradation Brite KEGG Orthology (KO) [BR:pon00001]  09100 Metabolism   09103 Lipid metabolism    00600 Sphingolipid metabolism     100172513 (SPHK2)  09130 Environmental Information Processing   09132 Signal transduction    04370 VEGF signaling pathway     100172513 (SPHK2)    04371 Apelin signaling pathway     100172513 (SPHK2)    04020 Calcium signaling pathway     100172513 (SPHK2)    04072 Phospholipase D signaling pathway     100172513 (SPHK2)    04071 Sphingolipid signaling pathway     100172513 (SPHK2)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     100172513 (SPHK2)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     100172513 (SPHK2)  09160 Human Diseases   09171 Infectious disease: bacterial    05152 Tuberculosis     100172513 (SPHK2) Enzymes [BR:pon01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.91  sphingosine kinase      100172513 (SPHK2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  DAGK_cat YegS_C Motif Other DBs NCBI-GeneID:  100172513 NCBI-ProteinID:  NP_001125597 Ensembl:  ENSPPYG00000010207 UniProt:  Q5RB28 LinkDB All DBs Position 20:54817946..54828670 Genome browser AA seq 654 aa AA seqDB search MNGHLEAEEQQDQRLDQELTGSWGHRPRSTLVRAKAMAPPPPPLAASTPLLHGEFGSYPA RGPRFALTLTSQALHIQRLRPKPEARPRGGLVPLAEVSGCCTLRSRSPSDSAAYFCIYTY PRGRRGARRRATRTFRADGAATYEENRAEAQRWATALTCLLRGLPLPGDGEITPDLLPRP PRLLLLVNPFGGRGLAWQWCKNHVLPMISEAGLSFNLIQTERQNHARELVQGLSLSEWDG IVTVSGDGLLHEVLNGLLDRPDWEEAVKMPVGILPCGSGNALAGAVNQHGGFEPALGLDL LLNCSLLLCRGGGHPLDLLSVTLASGSRCFSFLSVAWGFVSDVDIQSERFRALGSARFTL GTVLGLATLHTYRGRLSYLPATVEPASPTPAHSLPRAKSELTLTPDPAPPTAHSPLHRSV SDLPLPLPQPALASPGSPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKA AVHSPVSEGAPVIPPSSGLPLPTPDARVAASTCGPPDHLLPPLGTPLPPDWVTLEGDFVL MLAISPSHLGADLVAAPHARFDDGLVHLCWVRSGISRAALLRLFLAMERGSHFSLGCPQL GYAAARAFRLEPLTPRGVLTVDGEQVEYGPLQAQIHPGLGTLLTGPPGCPGREP NT seq 1965 nt NT seq  +upstreamnt  +downstreamnt atgaatggacaccttgaagcagaggagcagcaggaccagaggttggaccaggagctgacc gggagctggggccacaggcctaggagcaccctggtcagggctaaggccatggccccgccc ccaccgccactggctgccagcaccccgctcctccatggcgagtttggctcctacccagcc cgaggcccacgctttgccctcaccctcacatcgcaggccctgcacatacagcggctgcgc cccaaacccgaagccaggccccggggtggcctggtcccgttggccgaggtctcaggctgc tgcaccctgcgaagccgcagcccctcagactcagcggcctacttctgcatctacacctac cctcggggccggcgcggggcccggcgcagagccactcgcaccttccgggcagatggggcc gccacctacgaagaaaaccgtgccgaggcccagcgctgggccaccgccctcacctgtctg ctccgaggactgccactgcccggggatggggagatcacccctgacctgctacctcggcct ccccggttgctcctattggtcaatccctttggggggcggggcctggcctggcagtggtgt aagaaccacgtgcttcccatgatctctgaagctgggctgtccttcaacctcatccagaca gaacgacagaaccacgcccgggagctggtccaggggctgagcctgagtgagtgggatggc atcgtcacggtctcgggagacgggctgctccatgaggtgctgaacgggctcctagatcgc cctgactgggaggaagctgtgaagatgcctgtgggcatcctcccctgcggctcgggcaac gcgctggccggagcagtgaaccagcacgggggatttgagccagccctgggcctcgacctg ttgctcaactgctcactgttgctgtgccggggtggtggccacccactggacctgctctcc gtgacgctggcctcgggctcccgctgtttctccttcctatctgtggcctggggctttgtg tcagatgtggatatccagagtgagcgcttcagggccttgggcagtgcccgcttcacactg ggcacggtgctgggcctcgccacactgcacacctaccgcggacgcctctcctacctcccc gccactgtggaacccgcctcgcccacccctgcccatagcctgccccgtgccaagtcggag ctgaccctaaccccagacccagccccgcccacggcccactcacccctgcatcgttctgtg tctgacctgccccttcccctgccccagcctgccctggcctcccctggctcgccagaaccc ctgcccatcctgtccctcaacggtgggggcccagagctggctggggactggggtggggct ggggatgctccgctgtccccggacccactgctgtcttcacctcctggctctcccaaggca gctgtacactcacccgtctccgagggcgcccccgtaattcccccatcctctgggctccca cttcccacccctgatgcccgggtagcggcctccacctgcggcccgcccgaccacctgctg cctccgctgggcaccccactgcccccagactgggtgacgctggagggggactttgtgctc atgttggccatctcgcctagccacctaggcgctgacctggtggcagctccgcacgcgcgc ttcgacgacggcctggtgcacctgtgctgggtgcgtagcggcatctcgcgggctgcgctg ctgcgccttttcttggccatggagcgtggtagccacttcagcctgggctgtccgcagctg ggctacgccgcggcccgtgccttccgtctagagccgctcacgccgcgcggcgtgctcaca gtggacggggagcaggtagagtatgggccgctacaggcacagatacaccctggcctcggt acactgctcactgggcctcctggctgcccggggcgggagccctga

Pongo abelii (Sumatran orangutan): 100433232 Help Entry 100433232         CDS       T01416                                  Symbol SPHK1 Name (RefSeq) sphingosine kinase 1 isoform X2   KO K04718   sphingosine kinase [EC:2.7.1.91] Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon00600   Sphingolipid metabolism pon01100   Metabolic pathways pon04020   Calcium signaling pathway pon04071   Sphingolipid signaling pathway pon04072   Phospholipase D signaling pathway pon04148   Efferocytosis pon04370   VEGF signaling pathway pon04371   Apelin signaling pathway pon04666   Fc gamma R-mediated phagocytosis pon05152   Tuberculosis Module pon_M00100   Sphingosine degradation Brite KEGG Orthology (KO) [BR:pon00001]  09100 Metabolism   09103 Lipid metabolism    00600 Sphingolipid metabolism     100433232 (SPHK1)  09130 Environmental Information Processing   09132 Signal transduction    04370 VEGF signaling pathway     100433232 (SPHK1)    04371 Apelin signaling pathway     100433232 (SPHK1)    04020 Calcium signaling pathway     100433232 (SPHK1)    04072 Phospholipase D signaling pathway     100433232 (SPHK1)    04071 Sphingolipid signaling pathway     100433232 (SPHK1)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     100433232 (SPHK1)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     100433232 (SPHK1)  09160 Human Diseases   09171 Infectious disease: bacterial    05152 Tuberculosis     100433232 (SPHK1) Enzymes [BR:pon01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.91  sphingosine kinase      100433232 (SPHK1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  DAGK_cat YegS_C Motif Other DBs NCBI-GeneID:  100433232 NCBI-ProteinID:  XP_054393367 Ensembl:  ENSPPYG00000008657 LinkDB All DBs Position 19:91807024..91812235 Genome browser AA seq 384 aa AA seqDB search MDPAGGPRGVLPRPCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHA RELVRSEELGRWDALVVMSGDGLMHEVVNGLMERPDWETAIRKPLCSLPAGSGNALAASL NHYAGYEQVTSEDLLTNCTLLLCRRLLSPMNLLSLHTASGLHLFSVLSLAWGFIADVDLE SEKYRRLGEMRFTLGTFLRLAALRTYRGRLAYLPVGGVGSKTPASPVVVEQGPVDAHLVP LEEPVPSHWTVVPDQDFVLVLALLHSHLGSEMFAAPMGRCAAGVMHLFYVRAGVSRAMLL RLFLAMEKGRHMEYECPYLVYVPVVAFRLEPKDGRGVFAVDGELMVSEAVQGQVHPNYFW MVSGCVEPPPSWKPQQTPPPEEPL NT seq 1155 nt NT seq  +upstreamnt  +downstreamnt atggatccagcgggcggcccccggggcgtgctcccgcggccctgccgcgtgctggtgctg ctgaacccgcgcggcggcaagggcaaggccctgcagctcttccggagtcacgtgcagccc cttttggctgaggctgaaatctccttcacgctgatgctcactgagcggcggaaccatgcg cgggagctggtgcggtcggaggagctgggccgctgggacgctctggtggtcatgtctgga gacgggctgatgcacgaggtggtgaacgggctcatggagcggcctgactgggagaccgcc atccggaagcccctgtgtagcctaccagcaggctctggcaacgcgctggcagcttccttg aaccattatgctggctatgagcaggtcaccagtgaagacctcctgaccaactgcacgctg ttgctgtgccgccggctactgtcgcccatgaacctgctgtctctgcacacggcttcgggg ctgcacctcttctctgtgctcagcctggcctggggcttcattgctgatgtggacctagag agtgagaagtatcggcgtctgggggagatgcgcttcactctgggcaccttcctgcgtctg gccgccctgcgcacctaccgcggccgactggcctacctccctgtaggaggagtcggctcc aagacacctgcctcccccgttgtggtcgagcagggccccgtagatgcacaccttgtgcca ctggaggagccagtgccctctcactggacagtggtgcccgaccaggacttcgtgctagtc ctggcgctgctgcactcgcacctgggcagtgagatgtttgctgcacccatgggccgctgt gcagctggtgtcatgcatctgttctacgtgcgggcgggagtgtctcgggccatgctgctg cgcctcttcctggccatggagaagggcaggcatatggagtatgaatgcccctacttggta tacgtgcccgtggtcgccttccgcttagagcccaaggatgggagaggtgtgtttgcagtg gatggggaattgatggttagcgaggccgtgcagggccaggtgcacccaaactacttctgg atggtcagtggttgcgtggagcccccgcccagctggaagccccagcagacgccacctcca gaagagcccttatga

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