Pongo abelii (Sumatran orangutan): 100172513 Help Entry 100172513         CDS       T01416                                  Gene name SPHK2 Definition (RefSeq) sphingosine kinase 2   KO K04718   sphingosine kinase [EC:2.7.1.91] Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon00600   Sphingolipid metabolism pon01100   Metabolic pathways pon04020   Calcium signaling pathway pon04071   Sphingolipid signaling pathway pon04072   Phospholipase D signaling pathway pon04370   VEGF signaling pathway pon04371   Apelin signaling pathway pon04666   Fc gamma R-mediated phagocytosis pon05152   Tuberculosis Module pon_M00100   Sphingosine degradation Brite KEGG Orthology (KO) [BR:pon00001]  09100 Metabolism   09103 Lipid metabolism    00600 Sphingolipid metabolism     100172513 (SPHK2)  09130 Environmental Information Processing   09132 Signal transduction    04370 VEGF signaling pathway     100172513 (SPHK2)    04371 Apelin signaling pathway     100172513 (SPHK2)    04020 Calcium signaling pathway     100172513 (SPHK2)    04072 Phospholipase D signaling pathway     100172513 (SPHK2)    04071 Sphingolipid signaling pathway     100172513 (SPHK2)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     100172513 (SPHK2)  09160 Human Diseases   09171 Infectious disease: bacterial    05152 Tuberculosis     100172513 (SPHK2) Enzymes [BR:pon01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.91  sphingosine kinase      100172513 (SPHK2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  DAGK_cat Motif Other DBs NCBI-GeneID:  100172513 NCBI-ProteinID:  NP_001125597 Ensembl:  ENSPPYG00000010207 UniProt:  Q5RB28 LinkDB All DBs Position 19 AA seq 244 aa AA seqDB search MNGHLEAEEQQDQRLDQELTGSWGHRPRSTLVRAKAMAPPPPPLAASTPLLHSEFGSYPA RGPRFALTLTSQALHIQRLRPKPEARPRGGLVPLAEVSGCCTLRSRSPSDSAAYFCIYTY PRGRRGARRRATRTFRADGAATYEENRAEAQRWATALTCLLRGLPLPGDGEITPDLLPRP PRLLLLVNPFGGRGLAWQWCKNHVLPMISEAGLSFNLIQTERQNHARELVQGLSLSAERA PRSP NT seq 735 nt NT seq  +upstreamnt  +downstreamnt atgaatggacaccttgaagcagaggagcagcaggaccagaggttggaccaggagctgacc gggagctggggccacaggcctaggagcaccctggtcagggctaaggccatggccccgccc ccaccgccactggctgccagcaccccgctcctccatagcgagtttggctcctacccagcc cgaggcccacgctttgccctcaccctcacatcgcaggccctgcacatacagcggctgcgc cccaaacccgaagccaggccccggggtggcctggtcccgttggccgaggtctcaggctgc tgcaccctgcgaagccgcagcccctcagactcagcggcctacttctgcatctacacctac cctcggggccggcgcggggcccggcgcagagccactcgcaccttccgggcagatggggcc gccacctacgaagaaaaccgtgccgaggcccagcgctgggccaccgccctcacctgtctg ctccgaggactgccactgcccggggatggggagatcacccctgacctgctacctcggcct ccccggttgctcctattggtcaatccctttggggggcggggcctggcctggcagtggtgt aagaaccacgtgcttcccatgatctctgaagctgggctgtccttcaacctcatccagaca gaacgacagaaccacgcccgggagctggtccaggggctgagcctgagtgctgaacgggct cctagatcgccctga

Pongo abelii (Sumatran orangutan): 100433232 Help Entry 100433232         CDS       T01416                                  Gene name SPHK1 Definition (RefSeq) sphingosine kinase 1 isoform X1   KO K04718   sphingosine kinase [EC:2.7.1.91] Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon00600   Sphingolipid metabolism pon01100   Metabolic pathways pon04020   Calcium signaling pathway pon04071   Sphingolipid signaling pathway pon04072   Phospholipase D signaling pathway pon04370   VEGF signaling pathway pon04371   Apelin signaling pathway pon04666   Fc gamma R-mediated phagocytosis pon05152   Tuberculosis Module pon_M00100   Sphingosine degradation Brite KEGG Orthology (KO) [BR:pon00001]  09100 Metabolism   09103 Lipid metabolism    00600 Sphingolipid metabolism     100433232 (SPHK1)  09130 Environmental Information Processing   09132 Signal transduction    04370 VEGF signaling pathway     100433232 (SPHK1)    04371 Apelin signaling pathway     100433232 (SPHK1)    04020 Calcium signaling pathway     100433232 (SPHK1)    04072 Phospholipase D signaling pathway     100433232 (SPHK1)    04071 Sphingolipid signaling pathway     100433232 (SPHK1)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     100433232 (SPHK1)  09160 Human Diseases   09171 Infectious disease: bacterial    05152 Tuberculosis     100433232 (SPHK1) Enzymes [BR:pon01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.91  sphingosine kinase      100433232 (SPHK1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  DAGK_cat Motif Other DBs NCBI-GeneID:  100433232 NCBI-ProteinID:  XP_002827913 Ensembl:  ENSPPYG00000008657 UniProt:  H2NUT4 LinkDB All DBs Position 17 AA seq 470 aa AA seqDB search MSAQVLGFLRSWTPLPLAAPRDPAAAGNDAGAPTAKAPGGEGEPHSRPCDARLGSTDKEL KAGAAATGSAPTAQGTPWQREPRVEVMDPAGGPRGVLPRPCRVLVLLNPRGGKGKALQLF RSHVQPLLAEAEISFTLMLTERRNHARELVRSEELGRWDALVVMSGDGLMHEVVNGLMER PDWETAIRKPLCSLPAGSGNALAASLNHYAGYEQVTSEDLLTNCTLLLCRRLLSPMNLLS LHTASGLHLFSVLSLAWGFIADVDLESEKYRRLGEMRFTLGTFLRLAALRTYRGRLAYLP VGGVGSKTPASPVVVEQGPVDAHLVPLEEPVPSHWTVVPDQDFVLVLALLHSHLGSEMFA APMGRCAAGVMHLFYVRAGVSRAMLLRLFLAMEKGRHMEYECPYLVYVPVVAFRLEPKDG RGVFAVDGELMVSEAVQGQVHPNYFWMVSGCVEPPPSWKPQQTPPPEEPL NT seq 1413 nt NT seq  +upstreamnt  +downstreamnt atgtccgctcaagttctgggatttttacgcagctggactcccctccccctggcagccccg agggatccagccgccgcagggaatgacgccggtgctcctacagccaaggctccgggcggg gagggcgagccccacagccggccctgcgacgcccgcctgggcagcaccgataaggagctg aaggcaggagccgccgccacgggcagcgcccccacagcgcaggggaccccctggcagcgg gagccgcgggtcgaggttatggatccagcgggcggcccccggggcgtgctcccgcggccc tgccgcgtgctggtgctgctgaacccgcgcggcggcaagggcaaggccctgcagctcttc cggagtcacgtgcagccccttttggctgaggctgaaatctccttcacgctgatgctcact gagcggcggaaccatgcgcgggagctggtgcggtcggaggagctgggccgctgggacgct ctggtggtcatgtctggagacgggctgatgcacgaggtggtgaacgggctcatggagcgg cctgactgggagaccgccatccggaagcccctgtgtagcctaccagcaggctctggcaac gcgctggcagcttccttgaaccattatgctggctatgagcaggtcaccagtgaagacctc ctgaccaactgcacgctgttgctgtgccgccggctactgtcgcccatgaacctgctgtct ctgcacacggcttcggggctgcacctcttctctgtgctcagcctggcctggggcttcatt gctgatgtggacctagagagtgagaagtatcggcgtctgggggagatgcgcttcactctg ggcaccttcctgcgtctggccgccctgcgcacctaccgcggccgactggcctacctccct gtaggaggagtcggctccaagacacctgcctcccccgttgtggtcgagcagggccccgta gatgcacaccttgtgccactggaggagccagtgccctctcactggacagtggtgcccgac caggacttcgtgctagtcctggcgctgctgcactcgcacctgggcagtgagatgtttgct gcacccatgggccgctgtgcagctggtgtcatgcatctgttctacgtgcgggcgggagtg tctcgggccatgctgctgcgcctcttcctggccatggagaagggcaggcatatggagtat gaatgcccctacttggtatacgtgcccgtggtcgccttccgcttagagcccaaggatggg agaggtgtgtttgcagtggatggggaattgatggttagcgaggccgtgcagggccaggtg cacccaaactacttctggatggtcagtggttgcgtggagcccccgcccagctggaagccc cagcagacgccacctccagaagagcccttatga

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