Pongo abelii (Sumatran orangutan): 100447447
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Entry
100447447 CDS
T01416
Gene name
EZH2
Definition
(RefSeq) histone-lysine N-methyltransferase EZH2 isoform X1
KO
K11430
[histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:
2.1.1.356
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon00310
Lysine degradation
pon01100
Metabolic pathways
pon05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
100447447 (EZH2)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
100447447 (EZH2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
pon03036
]
100447447 (EZH2)
Enzymes [BR:
pon01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.356 [histone H3]-lysine27 N-trimethyltransferase
100447447 (EZH2)
Chromosome and associated proteins [BR:
pon03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
100447447 (EZH2)
Polycomb group proteins
PRC2-EZH2 complex
100447447 (EZH2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PRC2_HTH_1
SET
EZH2_WD-Binding
preSET_CXC
Motif
Other DBs
NCBI-GeneID:
100447447
NCBI-ProteinID:
XP_024105767
LinkDB
All DBs
Position
7
AA seq
751 aa
AA seq
DB search
MGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEW
KQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNF
MVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQ
YNDDDDDDDGDDPEEREEKQKDLEDHRDDKESRPPRKFPSDKIFEAISSMFPDKGTAEEL
KEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHRKC
NYSFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPPKRPGGRRR
GRLPNNSSRPSTPTINVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSSSEANSRCQ
TPIKMKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESS
IIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCP
CVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWD
SKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRG
KVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRA
IQTGEELFFDYRYSQADALKYVGIEREMEIP
NT seq
2256 nt
NT seq
+upstream
nt +downstream
nt
atgggccagactgggaagaaatctgagaagggaccagtttgttggcggaagcgtgtaaaa
tcagagtacatgcgactgagacagctcaagaggttcagacgggctgatgaagtaaagagt
atgtttagttccaatcgtcagaaaattttggaaagaacggaaatcttaaaccaagaatgg
aaacagcgaaggatacagcctgtgcacatcctgacttctgtgagctcattgcgcgggact
agggagtgttcggtgaccagtgacttggattttccaacacaagtcatcccattaaagact
ctgaatgcagttgcttcagtgcccataatgtattcttggtctcccctacagcagaatttt
atggtggaagatgaaactgttttacataacattccttatatgggagatgaagttttagac
caggatggtactttcattgaagaactaataaaaaattatgatggaaaagtacatggggat
agagaatgtgggtttataaatgatgaaatttttgtggagttggtgaatgcccttggtcaa
tataatgatgatgacgatgacgatgatggagacgatcctgaagaaagagaagaaaagcag
aaagatctggaggatcaccgagatgataaagaaagccgcccacctcggaaatttccttct
gataaaatttttgaagccatttcctcaatgtttccagataagggcacagcagaagaacta
aaggaaaaatataaagaactcaccgaacagcagctcccaggcgcacttcctcctgaatgt
acccccaacatagatggaccaaacgctaaatctgttcagagagagcaaagcttacactcc
tttcatacgcttttctgtaggcgatgttttaaatatgactgcttcctacatcgtaagtgc
aattattcctttcatgcaacacccaacacttataagcggaagaacacagaaacagctcta
gacaacaaaccttgtggaccacagtgttaccagcatttggagggagcaaaggagttcgct
gctgctctcaccgctgagcggataaagaccccaccaaaacgcccaggaggccgcagaaga
ggacggcttcccaataacagtagcaggcccagcacccccaccattaatgtgctggaatca
aaggatacagacagtgatagggaagcagggactgaaacggggggagagaacaatgataaa
gaagaagaagagaagaaagatgaaacttcgagctcctctgaagcaaattctcggtgtcaa
acaccaataaagatgaagccaaatattgaacctcctgagaatgtggagtggagtggtgct
gaagcctcaatgtttagagtcctcattggcacttactatgacaatttctgtgccattgct
aggttaattgggaccaaaacatgtagacaggtgtatgagtttagagtcaaagaatctagc
atcatagctccagctcccgctgaggatgtggatactcctccaaggaaaaagaagaggaaa
caccggttgtgggctgcgcactgcagaaagatacagctgaaaaaggacggctcctctaac
catgtttacaactatcaaccctgtgatcatccacggcagccttgtgacagttcgtgccct
tgtgtgatagcacaaaatttttgtgaaaagttttgtcaatgtagttcagagtgtcaaaac
cgctttccgggatgccgctgcaaagcacagtgcaacaccaagcagtgcccgtgctacctg
gctgtccgagagtgtgaccctgacctctgtcttacttgtggagccgctgaccattgggac
agtaaaaatgtgtcctgcaagaactgcagtattcagcggggctccaaaaagcatctattg
ctggcaccatctgatgtggcaggctgggggatttttatcaaagatcctgtgcagaaaaat
gaattcatctcagaatactgtggagagattatttctcaagatgaagctgacagaagaggg
aaagtatatgataaatacatgtgcagctttctgttcaacttgaacaatgattttgtggtg
gatgcaacccgcaagggtaacaaaattcgttttgcaaatcattcagtaaatccaaactgc
tatgcaaaagttatgatggttaacggtgatcacaggataggtatttttgccaagagagcc
atccagactggcgaagagctgttttttgattacagatacagccaggctgatgccctgaag
tatgtcggcatcgaaagagaaatggaaatcccttga
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integrated database retrieval system
