KEGG   Pongo abelii (Sumatran orangutan): 100453386
Entry
100453386         CDS       T01416                                 

Gene name
THBS1
Definition
(RefSeq) thrombospondin-1
  KO
K16857  thrombospondin 1
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon04015  Rap1 signaling pathway
pon04115  p53 signaling pathway
pon04145  Phagosome
pon04151  PI3K-Akt signaling pathway
pon04350  TGF-beta signaling pathway
pon04510  Focal adhesion
pon04512  ECM-receptor interaction
pon05144  Malaria
pon05165  Human papillomavirus infection
pon05205  Proteoglycans in cancer
pon05206  MicroRNAs in cancer
pon05219  Bladder cancer
Brite
KEGG Orthology (KO) [BR:pon00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    100453386 (THBS1)
   04350 TGF-beta signaling pathway
    100453386 (THBS1)
   04151 PI3K-Akt signaling pathway
    100453386 (THBS1)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    100453386 (THBS1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    100453386 (THBS1)
  09143 Cell growth and death
   04115 p53 signaling pathway
    100453386 (THBS1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100453386 (THBS1)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    100453386 (THBS1)
   05205 Proteoglycans in cancer
    100453386 (THBS1)
  09162 Cancer: specific types
   05219 Bladder cancer
    100453386 (THBS1)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    100453386 (THBS1)
  09174 Infectious disease: parasitic
   05144 Malaria
    100453386 (THBS1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pon04131]
    100453386 (THBS1)
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins [BR:pon00536]
    100453386 (THBS1)
   04990 Domain-containing proteins not elsewhere classified [BR:pon04990]
    100453386 (THBS1)
Membrane trafficking [BR:pon04131]
 Endocytosis
  Phagocytosis
   Opsonins
    100453386 (THBS1)
Glycosaminoglycan binding proteins [BR:pon00536]
 Heparan sulfate / Heparin
  Extracellular matrix molecules
   100453386 (THBS1)
Domain-containing proteins not elsewhere classified [BR:pon04990]
 Thrombospondin domain-containing proteins
  Thrombospondins
   100453386 (THBS1)
SSDB
Motif
Pfam: TSP_C TSP_3 TSP_1 TSP1_spondin VWC EGF_3 TSP1_ADAMTS EGF_CA Laminin_G_3 TSP1_CCN cEGF Laminin_G_2 EGF Laminin_G_1
Other DBs
NCBI-GeneID: 100453386
NCBI-ProteinID: XP_002825327
Ensembl: ENSPPYG00000006338
UniProt: H2NMT2 A0A663D9A9
LinkDB
Position
15
AA seq 1170 aa
MGLAWGLGILFLMHVCGTNRIPESGGDNSVFDIFELTGAARKGSGRRLVKGPDPSSPAFR
IEDANLIPPVPDDKFQDLVDAVRAEKGFLLLASLRQMKKTRGTLLALERKDHSGQVFSVV
SNGKAGTLDLSLTVQGKQHVVSVEEALLATGQWKSITLFVQEDRAQLYIDCEKMENAELD
VPIQSVFTRDLASIARLRIAKGGVNDNFQGVLQNVRFVFGTTPEDILRNKGCSSSTSVLL
TLDNNVVNGSSPAIRTNYIGHKTKDLQAICGISCDELSSMVLELRGLRTIVTTLQDSIRK
VTEENKELANELRRPPLCYHNGVQYRNNEEWTVDSCTECHCQNSVTICKKVSCPIMPCSN
ATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQT
RTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARE
TKACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQI
CNKQDCPIDGCLSNPCFAGVKCTSYPDGSWKCGACPAGYSGNGIQCTDVDECKEVPDACF
NHNGEHRCKNTDPGYNCLPCPPRFTGSQPFGQGVEHATANKQVCKPRNPCTDGTHDCNKN
AKCNYLGHYSEPMYRCECKPGYAGNGIICGEDTDLDGWPNENLVCVANATYHCKKDNCPN
LPNSGQEDYDKDGIGDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVGDRCDNCPYN
HNPDQADTDNNGEGDACAADIDGDGILNERDNCQYVYNVDQRDTDMDGVGDQCDNCPLEH
NPDQLDSDSDRIGDTCDNNQDIDEDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDDN
DGIPDDRDNCRLVPNPDQKDSDGDGRGDACKDDFDHDSVPDIDDICPENVDISETDFRRF
QMIPLDPKGTSQNDPNWVVRHQGKELVQTVNCDPGLAVGYDEFNAVDFSGTFFINTERDD
DYAGFVFGYQSSSRFYVVMWKQVTQSYWDTNPTRAQGYSGLSVKVVNSTTGPGEHLRNAL
WHTGNTPGQVRTLWHDPRHIGWKDFTAYRWRLSHRPKTGFIRVVMYEGKKIMADSGPIYD
KTYAGGRLGLFVFSQEMVFFSDLKYECRDP
NT seq 3513 nt   +upstreamnt  +downstreamnt
atggggctggcctggggactaggcatcctgttcctgatgcatgtgtgtggcaccaaccgc
attccagagtctgggggagacaacagcgtgtttgacatctttgaactcaccggggccgcc
cgcaaggggtctgggcgccgactggtgaagggccctgacccttccagcccagctttccgc
atcgaggatgccaacctgatcccccctgtgcctgatgacaagttccaagacctggtggat
gctgtgcgggcagaaaagggtttcctccttctggcctccctgaggcagatgaagaagacc
cggggcacgctgctggccctggagcggaaagaccactctggccaggtcttcagcgtggtg
tccaatggcaaggcgggcaccctggacctcagcctgaccgtccaaggaaagcagcacgtg
gtgtctgtggaagaagctctcctggcaaccggccagtggaagagcatcaccctgtttgtg
caggaagacagggcccagctgtacatcgactgtgaaaagatggagaatgctgagttggac
gtccccatccaaagcgtcttcaccagagacctggccagcatcgccagactccgcatcgca
aaggggggcgtcaatgacaatttccagggggtgctgcagaatgtgaggtttgtctttgga
accacaccagaagacatcctcaggaacaaaggctgctccagctctaccagtgtcctcctc
acccttgacaacaacgtggtgaatggttccagccctgccatccgcactaactacattggc
cacaagacaaaggacttgcaagccatctgcggcatctcctgtgatgagctgtccagcatg
gtcctggaactcaggggcctgcgcaccattgtcaccacgctgcaggacagcatccgcaaa
gtgactgaagagaacaaagagttggccaatgagctgaggcggcctcccctgtgctatcac
aacggagttcagtacagaaacaacgaggaatggactgttgatagctgcactgagtgtcac
tgtcagaactcagttaccatctgcaaaaaggtgtcctgccccatcatgccctgctccaat
gccacagttcctgatggagaatgctgccctcgctgttggcccagcgactctgcggacgat
ggctggtctccatggtctgagtggacctcctgttctacgagctgtggcaatggaattcag
cagcgcggccgctcctgcgatagcctcaacaaccgatgtgagggctcctcggtccagaca
cggacctgccacattcaggagtgtgacaagagatttaaacaggatggtggctggagccac
tggtccccgtggtcatcttgttctgtgacatgtggtgatggtgtgatcacaaggatccgg
ctctgcaactctcccagcccccagatgaacgggaaaccctgtgaaggcgaagcgcgggag
accaaagcctgcaagaaagatgcctgccccatcaatggaggctggggtccttggtcacca
tgggacatctgttctgtcacctgtggaggaggggtacagaaacgtagccgtctctgcaac
aaccccacaccccagtttggaggcaaggactgcgttggtgatgtgacagaaaaccagatc
tgcaacaagcaggactgtccaattgatggatgcctgtccaatccctgctttgccggcgtg
aaatgtactagctaccctgatggcagctggaaatgtggtgcttgtcccgctggttacagt
ggaaatggcatccagtgtacagatgttgatgagtgcaaagaagtgcctgatgcctgcttc
aaccacaatggagagcacaggtgtaagaacacggaccccggctacaactgcctgccctgc
ccgccacgcttcaccggctcacagcccttcggccagggtgtcgaacatgccacggccaac
aaacaggtgtgcaagccccgtaacccctgcacggatgggacccacgactgcaacaagaac
gccaagtgcaactacctgggccactatagcgagcccatgtaccgctgcgagtgcaagcct
ggctacgctggcaatggcatcatctgcggggaggacacagacctggatggctggcccaat
gagaacctggtgtgcgtggccaatgcgacttaccactgcaaaaaggataattgccccaac
ctccccaactcaggacaggaagactatgacaaggatggaattggtgatgcctgtgatgat
gacgatgacaatgataaaattccagatgacagggacaactgtccattccattacaaccca
gctcagtatgactatgacagagatgacgtcggagaccgctgtgacaactgtccctacaac
cacaacccagatcaggcagacacagacaacaatggggaaggagacgcctgtgctgcagac
attgatggagacggtatcctcaatgaacgggacaactgccagtacgtctacaatgtggac
cagagagacactgatatggatggggttggagatcagtgtgacaactgccccttggaacac
aatccggatcagctggactctgactcagaccgcattggagatacctgtgacaacaatcag
gatattgatgaagatggccaccagaacaatctggacaactgtccctatgtgcccaatgcc
aaccaggctgaccatgacaaagatggcaagggagatgcctgtgaccacgatgatgacaac
gatggcattcctgatgacagggacaactgcagactcgtgcccaatcctgaccagaaggac
tctgacggcgatggtcgaggtgatgcttgcaaagatgattttgaccatgacagtgttcca
gacatcgatgacatctgtcctgagaatgtggacatcagtgagaccgatttccgccgattc
cagatgattcctctggatcccaaagggacatcccaaaatgaccctaactgggttgtacgc
catcagggtaaagaactcgtccagactgtcaactgtgatcctggactcgctgtaggttat
gacgagtttaatgctgtggacttcagtggcaccttcttcatcaacaccgaaagagacgat
gactatgctggatttgtctttggctaccagtccagcagccgcttttatgttgtaatgtgg
aagcaagtcacccagtcctactgggacaccaaccccacgagggctcagggatactcgggc
ctttctgtgaaagttgtaaactccaccacagggcctggcgagcacctgcggaatgccctg
tggcacacaggaaacacccctggccaggtgcgcaccctgtggcatgaccctcgtcacata
ggctggaaagatttcaccgcctacagatggcgtctcagccacaggccaaagacgggtttc
attagagtggtgatgtatgaagggaagaaaatcatggctgactcaggacccatctatgat
aaaacctatgctggtggtagactagggttgtttgtcttctctcaagaaatggtgttcttc
tccgacctgaaatacgaatgtagagatccctaa

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