Pongo abelii (Sumatran orangutan): 100454731
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Entry
100454731 CDS
T01416
Gene name
FLT3
Definition
(RefSeq) receptor-type tyrosine-protein kinase FLT3 isoform X1
KO
K05092
fms-related tyrosine kinase 3 [EC:
2.7.10.1
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon04010
MAPK signaling pathway
pon04014
Ras signaling pathway
pon04151
PI3K-Akt signaling pathway
pon04640
Hematopoietic cell lineage
pon05200
Pathways in cancer
pon05202
Transcriptional misregulation in cancer
pon05221
Acute myeloid leukemia
pon05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100454731 (FLT3)
04014 Ras signaling pathway
100454731 (FLT3)
04151 PI3K-Akt signaling pathway
100454731 (FLT3)
09150 Organismal Systems
09151 Immune system
04640 Hematopoietic cell lineage
100454731 (FLT3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100454731 (FLT3)
05202 Transcriptional misregulation in cancer
100454731 (FLT3)
05230 Central carbon metabolism in cancer
100454731 (FLT3)
09162 Cancer: specific types
05221 Acute myeloid leukemia
100454731 (FLT3)
Enzymes [BR:
pon01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100454731 (FLT3)
Protein kinases [BR:
pon01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
100454731 (FLT3)
CD molecules [BR:
pon04090
]
Proteins
100454731 (FLT3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
ig
I-set
Ig_3
Ig_2
APH
Motif
Other DBs
NCBI-GeneID:
100454731
NCBI-ProteinID:
XP_024086677
Ensembl:
ENSPPYG00000005244
LinkDB
All DBs
Position
13
AA seq
993 aa
AA seq
DB search
MPALARGGGRLPLLVVLSAIIFGTITNQDLPVIKCVLINHKNNDSSVGKSSSYPMVSESP
EDLGCALRPQSAGTVYEAAAVEVDVSASITLQVLVDAPGNISCLWVFKHSSLNCQPHFDL
QNRGVVSMVILKMTETQAGEYLLFIQSEATNYTILFTVSIRNTLLYTLRRPYFRKMENQD
ALVCISESVPEPIVEWVLCDSQGESCKEESPAVVKKEEKVLHELFGTDIRCCARNELGRE
CTRLFTIDLNQTPQTTLPQLFLKVGEPLWIRCKAVHVNHGFGLTWELENKALEEGNYFEM
STYSTNRTMIRILFAFVSSVARNDTGYYTCSSSKHPSQSALVTIVEKGFINATNSSEDYE
IDQYEEFCFSVRFKAYPQIRCTWTFSRKSFPCEQKGLDDGYSISKFCNHKHQPGEYIFHA
ENDDAQLTKMFTLNIRRKPQVLAEASASQASCFSDGYPLPSWTWKKCSDKSPNCTEEITQ
GVWNRKANRKVFGQWVSSSTLNMSEAIKGFLVKCCAYNSLGTSCETILLNSPGPFPFIQD
NISFYATIGVCLLFIVVLTLLICHKYKKQFRYESQLQMVQVTGSSDNEYFYVDFREYEYD
LKWEFPRENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMS
ELKMMTQLGSHENIVNLLGACTLSGPIYLIFEYCCYGDLLNYLRSKREKFHRTWTEIFKE
HNFSFYPTFQSHPNSSMPGSREVQIHPDSDQISGLHGNSFHSEDEIDYENQKRLEEEEDL
NVLTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDIMSDS
NYVVRGNARLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYK
LIQNGFKMDQPFYATEEIYIIMQACWAFDSRKRPSFPNLTSFLGCQLADAEEAMYQNVDG
RVSERPHTYQNRRPFSREMDSGPLSPQTQVEDS
NT seq
2982 nt
NT seq
+upstream
nt +downstream
nt
atgccggcgttggcgcgcggcggcggccggctgccgctgctcgttgttttgtctgcaatc
atatttgggactattacaaatcaagatctgcctgtgatcaagtgtgttttaatcaatcat
aagaacaatgattcatcagtggggaagtcatcatcatatcccatggtgtcagaatcccca
gaagacctcgggtgtgcattgagaccccagagcgcagggacagtgtacgaagctgccgct
gtggaagtggatgtatctgcttccatcacattgcaagtgctggttgacgccccagggaac
atttcctgtctctgggtctttaagcacagctccctgaattgccagccacattttgattta
caaaacagaggagttgtttccatggtcattttgaaaatgacagaaacccaagctggagaa
tacctactttttattcagagtgaagctaccaattacacaatattgtttacagtgagtata
agaaataccctgctttacacattaagaagaccttactttagaaaaatggaaaaccaggac
gccctggtctgcatatctgagagcgttccagagccgatcgtggaatgggtgctttgcgat
tcacagggggaaagctgtaaagaagaaagtccagctgttgttaaaaaggaggaaaaagtg
cttcatgaattatttgggacggacataaggtgctgtgccagaaatgaactgggcagggaa
tgcaccaggctcttcacaatagatctaaatcaaactcctcagaccacattgccacaatta
tttcttaaagtaggggaacccttatggataaggtgcaaagctgttcatgtgaaccatgga
ttcgggctcacctgggaattagaaaacaaagcactcgaggagggcaactactttgagatg
agtacctattcaacaaacagaactatgatacggattctgtttgcttttgtatcatcagtg
gcaagaaacgacaccggatactacacttgttcctcttcaaagcatcccagtcaatcagct
ttggttaccatcgtagaaaagggatttataaatgctaccaattcaagtgaagattatgaa
attgaccaatatgaagagttttgtttttctgtcaggtttaaagcctacccacaaatcaga
tgtacgtggaccttctctcgaaaatcatttccttgtgagcaaaagggtctcgatgacgga
tacagcatatccaagttttgcaatcataagcaccagccaggagaatatatattccatgca
gaaaatgatgatgcccaattgaccaaaatgttcacgctgaatataagaaggaaacctcaa
gtgctcgcagaagcatcagcaagtcaggcgtcctgtttctcggatggatacccattacca
tcttggacctggaagaagtgttcagacaagtctcccaactgcacagaagagatcacacaa
ggagtctggaatagaaaggctaacagaaaagtatttggacagtgggtgtcgagcagtact
ctaaacatgagtgaagccataaaagggttcctggtcaagtgctgtgcatacaattccctt
ggcacatcttgtgagacgatccttttaaactctccaggccccttccctttcatccaagac
aacatctcattctatgcaacaattggtgtttgtctcctcttcattgtcgttttaaccctg
ctaatttgtcacaagtacaaaaagcaatttaggtatgaaagccagctacagatggtacag
gtgaccggctcctcagataatgagtacttctacgttgatttcagagaatatgaatatgat
ctcaaatgggagtttccaagagaaaatttagagtttgggaaggtactaggatcaggtgct
tttggaaaagtgatgaacgcaacagcttatggaattagcaaaacaggagtctcaatccag
gttgccgtcaaaatgctgaaagaaaaagcagacagctctgaaagagaggcactcatgtca
gaactcaagatgatgacccagctgggaagccacgagaatattgtgaatctgctgggggcg
tgcacactgtcaggaccaatttacttgatttttgaatactgttgctatggtgatcttctc
aactatctaagaagtaaaagagaaaaatttcacaggacttggacagagattttcaaggaa
cacaatttcagtttttaccccactttccaatcacatccaaattccagcatgcctggttca
agagaagttcagatacacccggactcggatcaaatctcagggcttcatgggaattcattt
cactctgaagatgaaattgattatgaaaaccaaaaaaggctggaagaagaggaagacttg
aatgtgcttacatttgaagatcttctttgctttgcatatcaagttgccaaaggaatggaa
tttctggaatttaagtcgtgtgttcacagagacctggccgccaggaacgtgctcgtcacc
cacgggaaggtggtgaagatatgtgactttggattggctcgagatatcatgagtgattcc
aactatgttgtcaggggcaatgcccgtctgcctgtaaaatggatggcccctgaaagcctg
tttgaaggcatctacaccattaagagtgatgtctggtcatacggaatattactgtgggaa
atattctcacttggtgtgaatccttaccctggcattccggttgatgctaacttctacaaa
ctgattcaaaatggatttaaaatggatcagccattttatgctacagaagaaatatacatt
ataatgcaagcctgctgggcttttgactcaaggaaacggccatccttccctaatttgact
tcatttttaggatgtcagctggcagatgcagaagaagcgatgtatcagaatgtggatggt
cgtgtttcggaacgtcctcacacctaccaaaacaggcgacctttcagcagagagatggat
tcggggccactctctccgcagactcaggtcgaagattcctag
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