KEGG   Pan paniscus (bonobo): 100971701
Entry
100971701         CDS       T02283                                 

Gene name
CACNA1C
Definition
(RefSeq) calcium voltage-gated channel subunit alpha1 C
  KO
K04850  voltage-dependent calcium channel L type alpha-1C
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04010  MAPK signaling pathway
pps04020  Calcium signaling pathway
pps04022  cGMP-PKG signaling pathway
pps04024  cAMP signaling pathway
pps04260  Cardiac muscle contraction
pps04261  Adrenergic signaling in cardiomyocytes
pps04270  Vascular smooth muscle contraction
pps04713  Circadian entrainment
pps04720  Long-term potentiation
pps04723  Retrograde endocannabinoid signaling
pps04724  Glutamatergic synapse
pps04725  Cholinergic synapse
pps04726  Serotonergic synapse
pps04727  GABAergic synapse
pps04728  Dopaminergic synapse
pps04742  Taste transduction
pps04911  Insulin secretion
pps04912  GnRH signaling pathway
pps04921  Oxytocin signaling pathway
pps04924  Renin secretion
pps04925  Aldosterone synthesis and secretion
pps04927  Cortisol synthesis and secretion
pps04929  GnRH secretion
pps04930  Type II diabetes mellitus
pps04934  Cushing syndrome
pps04935  Growth hormone synthesis, secretion and action
pps05010  Alzheimer disease
pps05020  Prion disease
pps05022  Pathways of neurodegeneration - multiple diseases
pps05031  Amphetamine addiction
pps05410  Hypertrophic cardiomyopathy
pps05412  Arrhythmogenic right ventricular cardiomyopathy
pps05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100971701 (CACNA1C)
   04020 Calcium signaling pathway
    100971701 (CACNA1C)
   04024 cAMP signaling pathway
    100971701 (CACNA1C)
   04022 cGMP-PKG signaling pathway
    100971701 (CACNA1C)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    100971701 (CACNA1C)
   04929 GnRH secretion
    100971701 (CACNA1C)
   04912 GnRH signaling pathway
    100971701 (CACNA1C)
   04921 Oxytocin signaling pathway
    100971701 (CACNA1C)
   04935 Growth hormone synthesis, secretion and action
    100971701 (CACNA1C)
   04924 Renin secretion
    100971701 (CACNA1C)
   04925 Aldosterone synthesis and secretion
    100971701 (CACNA1C)
   04927 Cortisol synthesis and secretion
    100971701 (CACNA1C)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    100971701 (CACNA1C)
   04261 Adrenergic signaling in cardiomyocytes
    100971701 (CACNA1C)
   04270 Vascular smooth muscle contraction
    100971701 (CACNA1C)
  09156 Nervous system
   04724 Glutamatergic synapse
    100971701 (CACNA1C)
   04727 GABAergic synapse
    100971701 (CACNA1C)
   04725 Cholinergic synapse
    100971701 (CACNA1C)
   04728 Dopaminergic synapse
    100971701 (CACNA1C)
   04726 Serotonergic synapse
    100971701 (CACNA1C)
   04720 Long-term potentiation
    100971701 (CACNA1C)
   04723 Retrograde endocannabinoid signaling
    100971701 (CACNA1C)
  09157 Sensory system
   04742 Taste transduction
    100971701 (CACNA1C)
  09159 Environmental adaptation
   04713 Circadian entrainment
    100971701 (CACNA1C)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100971701 (CACNA1C)
   05020 Prion disease
    100971701 (CACNA1C)
   05022 Pathways of neurodegeneration - multiple diseases
    100971701 (CACNA1C)
  09165 Substance dependence
   05031 Amphetamine addiction
    100971701 (CACNA1C)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    100971701 (CACNA1C)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    100971701 (CACNA1C)
   05414 Dilated cardiomyopathy
    100971701 (CACNA1C)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    100971701 (CACNA1C)
   04934 Cushing syndrome
    100971701 (CACNA1C)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:pps04040]
    100971701 (CACNA1C)
Ion channels [BR:pps04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   100971701 (CACNA1C)
SSDB
Motif
Pfam: Ion_trans CAC1F_C GPHH Ca_chan_IQ PKD_channel
Other DBs
NCBI-GeneID: 100971701
NCBI-ProteinID: XP_008972030
LinkDB
Position
12
AA seq 2215 aa
MLRAFVQPGTPAYQPLPSHLSANTEVKFKGTLVHEAQLNYFYISPGGSNYGSPRPAHANM
NANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPK
KQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPED
DSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSA
ILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLH
IALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQNGT
VCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLII
IGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPE
NEDEGMDEEKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWN
RFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAE
MLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKI
TRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFD
NFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLA
IAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKIELKSIT
ADGESPPATKINMDDLQPSENEDKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEK
AVPMPEASAFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRN
HILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSA
INVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQL
FKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFT
VSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQ
EQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLIL
LNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLI
VIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSR
ISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVF
GKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTE
GETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWA
EYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATL
FALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLEQANEELRAIIKKIWKRTSMKLLDQ
VVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGP
EIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFT
TQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAG
YPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNH
DTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLEC
LKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRG
WPPQLVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRARPVSLMVPSQAG
APGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILS
GGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRLSEEELQDSRVYVSSL
NT seq 6648 nt   +upstreamnt  +downstreamnt
atgcttcgagcctttgttcagcctggtacgcctgcataccagccgcttcccagccacctg
tctgccaacacggaggtcaagtttaagggtactttggtgcatgaagctcaactcaactat
ttctacatctctcctggaggttccaactatgggagcccacgccccgcccatgccaacatg
aatgccaatgcggcagcggggctggcccctgagcacatccccaccccgggggccgccctg
tcctggcaggcggccatcgacgcagcccggcaggctaagctgatgggcagcgctggcaat
gcgaccatctccacagtcagctccacgcagcggaagcggcagcaatatgggaaacccaag
aagcagggcagcaccacggccacacgcccgccccgagccctgctctgcctgaccctgaag
aaccccatccggagggcctgcatcagcattgtcgaatggaaaccatttgaaataattatt
ttactgactatttttgccaattgtgtggccttagcgatatatattccctttccagaagat
gattccaacgccaccaattccaacctggaacgagtggaatatctctttctcataattttt
acggtggaagcgtttttaaaagtaatcgcctatggactcctctttcaccccaatgcctac
ctccgcaacggctggaacctactagattttataattgtggttgtggggctttttagtgca
attttagaacaagcaaccaaagcagatggggcaaacgctctcggagggaaaggggccgga
tttgatgtgaaggcgctgagggccttccgcgtgctgcgccccctgcggctggtgtccgga
gtcccaagtctccaggtggtcctgaattccatcatcaaggccatggtccccctgctgcac
atcgccctgcttgtgctgtttgtcatcatcatctacgccatcatcggcttggagctcttc
atggggaagatgcacaagacctgctacaaccaggagggcatagcagatgttccagcagaa
gatgacccttccccttgtgcgctggaaacgggccatgggcggcagtgccagaatggcacg
gtgtgcaagcccggctgggatggtcccaagcacggcatcaccaactttgacaactttgcc
ttcgccatgctcacggtgttccagtgcatcaccatggagggctggacggacgtgctgtac
tgggtcaatgatgccgtaggaagggactggccctggatctattttgttacactaatcatc
atagggtcattttttgtacttaacttggttctcggtgtgcttagcggagagttttccaaa
gagagggagaaggccaaggcccggggagatttccagaagctgcgggagaagcagcagcta
gaagaggatctcaaaggctacctggattggatcactcaggccgaagacatcgatcccgag
aatgaggacgaaggcatggatgaggagaagccccgaaacatgagcatgcccaccagtgag
accgagtccgtcaacaccgaaaacgtggctggaggtgacatcgagggagaaaactgcggg
gccaggctggcccaccggatctccaagtcaaagttcagccgctactggcgccggtggaat
cggttctgcagaaggaagtgccgcgccgcagtcaagtctaatgtcttctactggctggtg
attttcctggtgttcctcaacacgctcaccattgcctctgagcactacaaccagccccac
tggctcacagaagtccaagacacggcgaacaaggccctgctggccctgttcacggcggag
atgctcctgaagatgtacagcctgggcctgcaggcctacttcgtgtccctcttcaaccgc
tttgactgcttcgtcgtgtgtggtggcatcctggagaccatcctggtggagaccaagatc
atgtccccactgggcatctccgtgctcagatgcgtccggctgctgaggattttcaagatc
acgaggtactggaactccttgagcaacctggtggcatccttgctgaactctgtgcgctcc
atcgcctccctgctccttctcctcttcctcttcatcatcatcttctccctcctggggatg
cagctctttggaggaaagttcaactttgatgagatgcagacccggaggagcacattcgat
aacttcccccagtccctcctcactgtgtttcagatcctgaccggggaggactggaattcg
gtgatgtatgatgggatcatggcttatggcggcccctcttttccagggatgttagtctgt
atttacttcatcatcctcttcatctgtggaaactatatcctactgaatgtgttcttggcc
attgctgtggacaacctggctgatgctgagagcctcacatctgcccaaaaggaggaggaa
gaggagaaggagagaaagaagctggccaggactgccagcccagagaagaaacaagagttg
gtggagaagccagcagtgggggaatccaaggaggagaagattgagctgaaatccatcacg
gctgacggagagtctccacccgccaccaagatcaacatggatgacctccagcccagtgaa
aatgaggataagagcccctaccccaacccagaaactacaggagaagaggatgaggaggag
ccagagatgcctgtcggccctcgcccacgaccactctctgagcttcaccttaaggaaaag
gcagtgcccatgccagaagccagcgcgtttttcatcttcagctctaacaacaggtttcgc
ctccagtgccaccgcattgtcaatgacacgatcttcaccaacctgatcctcttcttcatt
ctgctcagcagcatttccctggctgctgaggacccggtccagcacacctccttcaggaac
catattctgttttattttgatattgtttttaccaccattttcaccattgaaattgctctg
aagatgactgcttatggggctttcctgcacaagggctctttctgccggaactacttcaac
atcctggacctgctggtggtcagcgtgtccctcatctcctttggcatccagtccagtgca
atcaatgtcgtgaagatcttgcgagtcctgcgagtactcaggcccctgagggccatcaac
agggccaaggggctaaagcatgtggttcagtgtgtgtttgtcgccatccggaccatcggg
aacatcgtgattgtcaccaccctgctgcagttcatgtttgcctgcatcggggtccagctc
ttcaagggaaagctgtacacctgttcagacagttccaagcagacagaggcggaatgcaag
ggcaactacatcacgtacaaagatggggaggttgaccaccccatcatccaaccccgcagc
tgggagaacagcaagtttgactttgacaatgttctggcagccatgatggccctcttcacc
gtctccaccttcgaagggtggccagagctgctgtaccgctccatcgactcccacacggaa
gacaagggccccatctacaactaccgtgtggagatatccatcttcttcatcatctacatc
atcatcatcgccttcttcatgatgaacatcttcgtgggcttcgtcatcgtcacctttcag
gagcagggggagcaggagtacaagaactgtgagctggacaagaaccagcgacagtgcgtg
gaatacgccctcaaggcccggcccctgcggaggtacatccccaagaaccagcaccagtac
aaagtgtggtacgtggtcaactccacctacttcgagtacctgatgttcgtcctcatcctg
ctcaacaccatctgcctggccatgcagcactacggccagagctgcctgttcaaaatcgcc
atgaacatcctcaacatgctcttcactggcctcttcaccgtggagatgatcctgaagctc
attgccttcaaacccaagggttactttagtgatccctggaatgtttttgacttcctcatc
gtaattggcagcataattgacgtcattctcagtgagactaatcactatttctgtgatgca
tggaatacatttgacgccttgattgttgtgggtagcattgttgatatagcaatcaccgag
gtaaacccagctgaacatacccaatgctctccctctatgaacgcagaggaaaactcccgc
atctccatcaccttcttccgcctgttccgggtcatgcgtctggtgaagctgctgagccgt
ggggagggcatccggacgctgctgtggaccttcatcaagtccttccaggccctgccctat
gtggccctcctgatcgtgatgctgttcttcatctacgcggtgatcgggatgcaggtgttt
gggaaaattgccctgaatgataccacagagatcaaccggaacaacaactttcagaccttc
ccccaggctgtgctgctcctcttcaggtgtgccaccggggaggcctggcaggacatcatg
ctggcctgcatgccaggcaagaagtgtgccccggagtccgagcccagcaacagcacggag
ggtgaaacaccctgtggtagcagctttgctgtcttctacttcatcagcttctacatgctc
tgtgccttcctgatcatcaacctctttgtagctgtcatcatggacaactttgactacctg
acaagggactggtccatccttggtccccaccacctggatgagtttaaaagaatctgggca
gagtatgaccctgaagccaagggtcgtatcaaacacctggatgtggtgaccctcctccgg
cggattcagccgccactaggtttcgggaagctgtgccctcaccgcgtggcttgcaaacgc
ctggtctccatgaacatgcctctgaacagcgacgggacagtcatgttcaatgccactctg
tttgccctggtcaggacggccctgaggatcaaaacagaagagggacccagcccatcagag
gcccaccaaggggctgaggatcctttccgccctgcagggaacctagaacaagccaatgag
gagctgcgggcgatcatcaagaagatctggaagcggaccagcatgaagctgctggaccag
gtggtgccccctgcaggtgatgatgaggtcaccgttggcaagttctacgccacgttcctg
atccaggagtatttccggaagttcaagaagcgcaaagagcagggccttgtgggcaagccc
tcccagaggaacgcgctgtctctgcaggctggcttgcgcacactgcatgacatcgggcct
gagatccgacgggccatctctggagatctcaccgctgaggaggagctggacaaggccatg
aaggaggctgtgtccgctgcttctgaagatgacatcttcaggagggccggtggcctgttc
ggcaaccacgtcagctactaccaaagcgacggccggagcgccttcccccagaccttcacc
actcagcgcccgctgcacatcaacaaggcgggcagcagccagggcgacactgagtcgcca
tcccacgagaagctggtggactccaccttcaccccgagcagctactcgtccaccggctcc
aacgccaacatcaacaacgccaacaacaccgccctgggtcgcctccctcgccccgccggc
taccccagcacggtcagcactgtggagggccacgggccccccttgtcccctgccatccgg
gtgcaggaggtggcgtggaagctcagctccaacaggtgccactcccgggagagccaggca
gccatggcgggtcaggaggagacgtctcaggatgagacctatgaagtgaagatgaaccat
gacacggaggcctgcagtgagcccagcctgctctccacagagatgctctcctaccaggat
gacgaaaatcggcaactgacgctcccagaggaggacaagagggacatccggcaatctcca
aagaggggtttcctccgctctgcctcactaggtcgaagggcctccttccacctggaatgt
ctgaagcgacagaaggaccgagggggagacatctctcagaagacagtcctgcccttgcat
ctggttcatcatcaggcattggcagtggcaggcctgagccccctcctccagagaagccat
tcccctgcctcattccctaggccttttgccaccccaccagccacacctggtagccgaggc
tggcccccacagctcgtccccaccctgcggctggagggggtcgagtccagtgagaaactc
aacagcagcttcccatccatccactgcggatcctgggctgagaccacccccggtggcggg
ggcagcagcgccgcccggagagcccggcccgtctccctcatggtgcccagccaggctggg
gccccagggaggcagttccacggcagtgccagcagcctggtggaagcggtcttgatttca
gaaggactggggcagtttgctcaagatcccaagttcatcgaggtcaccacccaggagctg
gccgacgcctgcgacatgaccatagaggagatggagagcgcggccgacaacatcctcagc
gggggcgccccacagagccccaatggcgccctcttaccctttgtgaactgcagggacgcg
gggcaggaccgagccgggggcgaagaggacgcgggctgtgtgcgcgcgcggggtcgactg
agtgaggaggagctccaggacagcagggtctacgtcagcagcctgtag

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