Pan troglodytes (chimpanzee): 107976801
Help
Entry
107976801 CDS
T01005
Symbol
ABL1
Name
(RefSeq) tyrosine-protein kinase ABL1 isoform X1
KO
K06619
abelson tyrosine-protein kinase 1 [EC:
2.7.10.2
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr04012
ErbB signaling pathway
ptr04014
Ras signaling pathway
ptr04110
Cell cycle
ptr04360
Axon guidance
ptr04722
Neurotrophin signaling pathway
ptr05200
Pathways in cancer
ptr05206
MicroRNAs in cancer
ptr05208
Chemical carcinogenesis - reactive oxygen species
ptr05220
Chronic myeloid leukemia
ptr05416
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
107976801 (ABL1)
04014 Ras signaling pathway
107976801 (ABL1)
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
107976801 (ABL1)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
107976801 (ABL1)
09158 Development and regeneration
04360 Axon guidance
107976801 (ABL1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
107976801 (ABL1)
05206 MicroRNAs in cancer
107976801 (ABL1)
05208 Chemical carcinogenesis - reactive oxygen species
107976801 (ABL1)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
107976801 (ABL1)
09166 Cardiovascular disease
05416 Viral myocarditis
107976801 (ABL1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ptr01001
]
107976801 (ABL1)
Enzymes [BR:
ptr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
107976801 (ABL1)
Protein kinases [BR:
ptr01001
]
Non-receptor tyrosine kinases
ABL family
107976801 (ABL1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
F_actin_bind
SH2
SH3_1
SH3_2
SH3_9
Haspin_kinase
Kinase-like
SH3_6
Motif
Other DBs
NCBI-GeneID:
107976801
NCBI-ProteinID:
XP_016817367
Ensembl:
ENSPTRG00000021477
ENSPTRG00000050265
VGNC:
4596
UniProt:
A0A2I3S7G9
A0A2I3RAJ1
LinkDB
All DBs
Position
11:complement(7569519..7740674)
Genome browser
AA seq
1149 aa
AA seq
DB search
MGQQPGKVLGDQRRPSLPALHFIKGAGKKESSRHGGPHCNVFVEHEALQRPVASDFEPQG
LSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCE
AQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQR
SISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRN
KPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVE
EFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLL
YMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKF
PIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERP
EGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVST
LLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPE
GGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDI
SNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATG
EEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPA
LPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQ
VTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKASSGAPGGTSKGPAEESRVRRHKHS
SESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAV
NSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTA
FIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGK
NLYTFCVSYVDSIQQMRNKFAFREAINKLENNLRELQICPATAGSGPAATQDFSKLLSSV
KEISDIVQR
NT seq
3450 nt
NT seq
+upstream
nt +downstream
nt
atggggcagcagcctggaaaagttcttggggaccaaagaaggccaagcttgcctgccctg
cattttatcaaaggagcagggaagaaggaatcatcgaggcatgggggtccacactgcaat
gtttttgtggaacatgaagcccttcagcggccagtagcatctgactttgagcctcagggt
ctgagtgaagccgctcgttggaactccaaggaaaaccttctcgctggacccagtgaaaat
gaccccaaccttttcgttgcactgtatgattttgtggccagtggagataacactctaagc
ataactaaaggtgaaaagctccgggtcttaggctataatcacaatggggaatggtgtgaa
gcccaaaccaaaaatggccaaggctgggtcccaagcaactacatcacgccagtcaacagt
ctggagaaacactcctggtaccatgggcctgtgtcccgcaatgctgctgagtatctgctg
agcagcgggatcaatggcagcttcttggtgcgtgagagtgagagcagtcctggccagagg
tccatctcgctgagatacgaagggagggtgtaccattacaggatcaacactgcttctgat
ggcaagctctacgtctcctccgagagccgcttcaacaccctggccgagttggttcatcat
cattcaacggtggccgacgggctcatcaccacgctccattatccagccccaaagcgcaac
aagcccactgtctacggtgtgtcccccaactacgacaagtgggagatggaacgcacggac
atcaccatgaagcacaagctgggtgggggccagtacggggaggtgtacgagggtgtgtgg
aagaaatacagcctgacggtggccgtgaagaccttgaaggaggacaccatggaggtggaa
gagttcttgaaagaagctgcagtcatgaaagagatcaaacaccctaacctggtgcagctc
cttggggtctgcacccgggagcccccgttctatatcatcactgagttcatgacctacggg
aacctcctggactacctgagggagtgcaaccggcaggaggtgaacgccgtggtgctgctg
tacatggccactcagatctcgtcagccatggagtacctggagaagaaaaacttcatccac
agagatcttgctgcccgaaactgcctggtaggggagaaccacttggtgaaggtagctgat
tttggcctgagcaggttgatgacaggggacacctacacagcccatgctggagccaagttc
cccatcaaatggactgcacccgagagcctggcctacaacaagttctccatcaagtccgac
gtctgggcatttggagtattgctttgggaaattgctacctatggcatgtccccttacccg
ggaattgacctgtcccaggtgtatgagctgctagagaaggactaccgcatggagcgccca
gaaggctgcccagagaaggtctatgaactcatgcgagcatgttggcagtggaatccctct
gaccggccctcctttgctgaaatccaccaagcctttgaaacaatgttccaggaatccagt
atctcagacgaagtggaaaaggagctggggaaacaaggcgtccgtggggctgtgagtacc
ttgctgcaggccccagagctgcccaccaagacaaggacctccaggagagctgcagagcac
agagacaccactgacgtgcctgagatgcctcactccaagggccagggagagagcgatcct
ctggaccatgagcctgccgtgtctccattgctccctcgaaaagagcgaggtcccccggag
ggcggcctgaatgaagatgagcgccttctccccaaagacaaaaagaccaacttgttcagc
gccttgatcaagaagaagaagaagacagccccaacccctcccaaacgcagcagctccttc
cgggagatggacggccagccggagcgcagaggggccggcgaggaagagggccgagacatc
agcaacggggcgctggctttcacccccttggacacagctgacccagccaagtccccaaag
cccagcaatggggctggggtccccaatggagccctccgggagtccgggggctcaggcttc
cggtctccccacctgtggaagaagtccagcacgctgaccagcagccgcctagccaccggc
gaggaggagggcggtggcagctccagcaagcgcttcctgcgctcctgctcggcctcctgc
gttccccatggggccaaggacacggagtggaggtcagtcacgctgcctcgggacttgcag
tccacgggaagacagtttgactcgtccacatttggagggcacaaaagtgagaagccggct
ctgcctcggaagagggcaggggagaacaggtctgaccaggtgacccgaggcacagtaacg
ccccctcccaggctggtgaaaaagaatgaggaagctgctgatgaggtcttcaaagacatc
atggagtccagcccgggctccagcccgcccaacctgactccaaaacccctccggcggcag
gtcaccgtggcccctgcctcgggcctcccccacaaggaagaagctggaaagggcagtgcc
ttagggacccctgctgcagctgagccagtgacccccaccagcaaagcaagctcaggtgca
ccagggggcaccagcaagggccccgccgaggagtccagagtgaggaggcacaagcactcc
tctgagtcgccagggagggacaaggggaaattgtccaggctcaaacctgccccgccgccc
ccaccagcagcctctgcagggaaggctggaggaaagccctcgcagagcccgagccaggag
gcggccggggaggcagtcctgggcgcaaagacaaaagccacgagtctggttgatgctgtg
aacagtgacgctgccaagcccagccagccgggagagggcctcaaaaagcccgtgctcccg
gccactccaaagccacagtccgccaagccgtcggggacccccatcagcccagcccccgtt
ccctccacgttgccatcagcatcctcggccctggcaggggaccagccatcttccaccgcc
ttcatccctctcatatcaacccgagtgtctcttcggaaaacccgccagcctccagagcgg
atcgccagtggcgccatcaccaagggcgtggtcctggacagcaccgaggcgctgtgcctc
gccatctctaggaactccgagcagatggccagccacagcgcagtgctggaggccggcaaa
aacctctacacgttctgcgtgagctacgtggattccatccagcaaatgaggaacaagttt
gccttccgagaggccatcaacaaactggagaataatctccgggagcttcagatctgcccg
gcgacagcaggcagtggtccggcggccactcaggacttcagcaagctcctcagttcggtg
aaggaaatcagtgacatagtgcagaggtag
Pan troglodytes (chimpanzee): 458694
Help
Entry
458694 CDS
T01005
Symbol
BCR
Name
(RefSeq) breakpoint cluster region protein isoform X1
KO
K08878
breakpoint cluster region protein [EC:
2.7.11.1
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr05200
Pathways in cancer
ptr05220
Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
458694 (BCR)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
458694 (BCR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ptr01001
]
458694 (BCR)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ptr04131
]
458694 (BCR)
Enzymes [BR:
ptr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
458694 (BCR)
Protein kinases [BR:
ptr01001
]
Serine/threonine kinases: Other
BCR family
458694 (BCR)
Membrane trafficking [BR:
ptr04131
]
Others
Rho GTPase associated proteins
Rho GTPase-activating proteins
458694 (BCR)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RhoGAP
Bcr-Abl_Oligo
RhoGEF
PH_19
C2
SOS1_NGEF_PH
IQ_SEC7_PH
RHG20_PH
PH_5
PH
Motif
Other DBs
NCBI-GeneID:
458694
NCBI-ProteinID:
XP_016795020
Ensembl:
ENSPTRG00000014138
VGNC:
10390
LinkDB
All DBs
Position
23:25198613..25336065
Genome browser
AA seq
1294 aa
AA seq
DB search
MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQ
TLLAKEKKSYDRQRWGFRRAAQAPDGASEPRGSASRPQPAPADGADPPPAEEPEARPDGE
GSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV
EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRTSESSC
GVDGDYEDAELNPRFLKDNLIDANGGSRPPWPPLEYQPYQSIYVGGMMEGEGKGPLLRSQ
STSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY
RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEG
AFHGDADGSFGTPPGYGCAADRAEEQRRHQDGLPYIDDSPSSSPHLSSKGRGSRDALVSG
ALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTS
QQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGV
AMEMAEKCCQANAQFAEISENLRARSNKDAKDPTTKNSLETLLYKPVDRVTRSTLVLHDL
LKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVE
GARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVP
DEELDALKIKISQIKSDIQREKRANKGSKATERLKKKLSEQESLLLLMSPSMAFRVHSRN
GKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTIN
KEDDESPGLYGFLNVIVHSATGFKQSSNLYCTLEVDSFGYFVNKAKTRVYRDTAEPNWNE
EFEIELEGSQTLRILCYEKCYNKTKIPKEDGESTDRLMGKGQVQLDPQALQDRDWQRTVI
AMNGIEVKLSVKFNSREFSLKRMPSRKQTGVFGVKIAVVTKRERSKVPYIVRQCVEEIER
RGMEEVGIYRVSGVATDIQALKAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLF
TDEFYPNFAEGIALSDPVAKESCMLNLLLSLPEANLLTFLFLLDHLKRVAEKEAVNKMSL
HNLATVFGPTLLRPSEKESKLPANPSQPITMTDSWSLEVMSQGPRAGGCFGSTAMSYQPP
ASKACVVAKPVWGWGTQHSPGGGPGSPSAMQAKA
NT seq
3885 nt
NT seq
+upstream
nt +downstream
nt
atggtggacccggtgggcttcgcggaggcgtggaaggcgcagttcccggactcagagccg
ccgcgcatggagctgcgctcagtgggcgacatcgagcaggagctggagcgctgcaaggcc
tccattcggcgcctggagcaggaggtgaaccaggagcgcttccgcatgatctacctgcag
acgttgctggccaaggaaaagaagagctatgaccggcagcgatggggcttccggcgcgcg
gcgcaggcccccgacggcgcctccgagccccgagggtccgcgtcgcgcccgcagccagcg
cccgccgacggagccgacccgccgcccgccgaggagcccgaggcccggcccgacggcgag
ggttctccgggtaaggccaggcccgggaccgcccgcaggcccggggcagccgcgtcgggg
gaacgggacgaccggggaccccccgccagcgtggcggcgctcaggtccaacttcgagcgg
atccgcaagggccatggccagcccggggcggacgccgagaagcccttctacgtgaacgtc
gagtttcaccacgagcgcggcctggtgaaggtcaacgacaaagaggtgtcggaccgcatc
agctctctgggcagccaggccatgcagatggagcgcaaaaagtcccagcacggcgcgggc
tcgagcgtgggggatgcatccaggcccccttaccggggacgcacctcggagagcagctgc
ggcgtcgacggcgactacgaggacgccgagttgaacccccgcttcctgaaggacaacctg
atcgacgccaatggcggtagcaggcccccttggccgcccctggagtaccagccctaccag
agcatctacgtcgggggcatgatggaaggggagggcaagggcccgctcctgcgcagccag
agcacctctgagcaggagaagcgccttacctggccccgcaggtcctactccccccggagt
tttgaggattgcggaggcggctataccccggactgcagctccaatgagaacctcacctcc
agcgaggaggacttctcctctggccagtccagccgcgtgtccccaagccccaccacctac
cgcatgttccgggacaagagccgttctccctcgcagaactcgcaacagtccttcgacagc
agcagtccccccacgccgcagtgccataagcggcaccggcactgcccggttgtcgtgtcc
gaggccaccatcgtgggcgtccgcaagaccgggcagatctggcccaacgatggcgagggc
gccttccatggagacgcagatggctcgttcggaacaccacctggatacggctgcgctgca
gaccgggcagaggagcagcgccggcaccaagatgggctgccctacattgatgactcgccc
tcctcatcgccccacctcagcagcaaaggcaggggcagccgggatgcgctggtctcggga
gccctggagtccactaaagcgagtgagctggacttggaaaagggcttggagatgagaaaa
tgggtcctgtctggaatcctggctagcgaggaaacttacctgagccacctggaggcactg
ctgctgcccatgaagcctttgaaagccgctgccaccacctctcagccggtgctgacgagt
cagcagatcgagaccatcttcttcaaagtgcctgagctctacgagatccacaaggagttc
tatgatgggctcttcccccgcgtgcagcagtggagccaccagcagcgggtgggcgacctc
ttccagaagctggccagccagttgggtgtgtaccgggccttcgtggacaactacggagtt
gccatggaaatggctgagaagtgctgtcaggccaatgctcagtttgcagaaatctccgag
aacctgagagccagaagcaacaaagatgccaaggatccaacgaccaagaactctctggaa
actctgctctacaagcctgtggaccgtgtgacgaggagcacgctggtcctccatgacttg
ctgaagcacactcctgccagccaccctgaccaccccttgctgcaggacgccctccgcatc
tcacagaacttcctgtccagcatcaacgaggagatcacaccccgacggcagtccatgacg
gtgaagaagggagagcaccggcagctgctgaaggacagcttcatggtggagctggtggag
ggggcccgcaagctgcgccacgtcttcctgttcaccgacctgcttctctgcaccaagctc
aagaagcagagcggaggcaaaacgcagcagtatgactgcaaatggtacattccgctcacg
gatctcagcttccagatggtggatgaattggaggcagtgcccaacatccccctggtgccc
gatgaggagctggacgctttgaagatcaagatctcccagatcaagagtgacatccagaga
gagaagagggcgaacaagggcagcaaggccacagagaggctgaagaagaagctgtcggag
caggagtcgctgctgctgcttatgtctcccagcatggccttcagggtgcacagccgcaac
ggcaagagttacacgttcctgatctcctctgactatgagcgtgcagagtggagggagaac
atccgggagcagcagaagaagtgtttcagaagcttctccctgacatccgtggagctgcag
atgctgaccaactcgtgtgtgaaactccagaccgtccacagcattccgctgaccatcaac
aaggaagatgatgagtctccggggctctatgggtttctgaatgtcatcgtccactcagcc
actggatttaagcagagttcaaatctgtactgcaccctggaggtggattcctttgggtat
tttgtgaataaagcaaagacgcgcgtctacagggacacagctgagccaaactggaacgag
gaatttgagatagagctggagggctcccagaccctgaggatactgtgctatgaaaagtgt
tacaacaagacgaagatccccaaggaggacggcgagagcacggacagactcatggggaag
ggccaggtccagctggacccgcaggccctgcaggacagagactggcagcgcaccgtcatc
gccatgaatgggatcgaagtaaagctctcggtcaagttcaacagcagggagttcagcttg
aagaggatgccatcccgaaaacagacaggggtcttcggagtcaagattgctgtggtcacc
aagagagagaggtccaaggtgccctacatcgtgcgccagtgcgtggaggagatcgagcgc
cgaggcatggaggaggtgggcatctaccgcgtgtccggtgtggccacggacatccaggca
ctgaaggcagccttcgacgtcaataacaaggacgtgtcggtgatgatgagcgagatggac
gtgaacgccatcgcaggcacgctgaagctgtacttccgtgagctgcccgagcccctcttc
actgacgagttctaccccaacttcgcagagggcatcgctctttcagacccggttgcaaag
gagagctgcatgctcaacctgctgctgtccctgccggaggccaacctgctcaccttcctt
ttccttctggaccacctgaaaagggtggcagagaaggaggcagtcaataagatgtccctg
cacaacctcgccacggtctttggccccacgctgctccggccctccgagaaggagagcaag
ctccctgccaaccccagccagcctatcaccatgactgacagctggtccttggaggtcatg
tcccagggtcccagggctggtggttgctttgggtctacagctatgtcttaccagcctcct
gcctcaaaagcctgtgtggtggcaaagccggtgtggggctggggaacgcagcattctcca
ggagggggacccggctctccttctgcaatgcaggcaaaggcctag
DBGET
integrated database retrieval system
