Pan troglodytes (chimpanzee): 450445
Help
Entry
450445 CDS
T01005
Symbol
MAPK8
Name
(RefSeq) mitogen-activated protein kinase 8 isoform X1
KO
K04440
mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:
2.7.11.24
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr01522
Endocrine resistance
ptr04010
MAPK signaling pathway
ptr04012
ErbB signaling pathway
ptr04014
Ras signaling pathway
ptr04024
cAMP signaling pathway
ptr04068
FoxO signaling pathway
ptr04071
Sphingolipid signaling pathway
ptr04137
Mitophagy - animal
ptr04140
Autophagy - animal
ptr04141
Protein processing in endoplasmic reticulum
ptr04210
Apoptosis
ptr04215
Apoptosis - multiple species
ptr04217
Necroptosis
ptr04310
Wnt signaling pathway
ptr04380
Osteoclast differentiation
ptr04510
Focal adhesion
ptr04530
Tight junction
ptr04620
Toll-like receptor signaling pathway
ptr04621
NOD-like receptor signaling pathway
ptr04622
RIG-I-like receptor signaling pathway
ptr04625
C-type lectin receptor signaling pathway
ptr04657
IL-17 signaling pathway
ptr04658
Th1 and Th2 cell differentiation
ptr04659
Th17 cell differentiation
ptr04660
T cell receptor signaling pathway
ptr04664
Fc epsilon RI signaling pathway
ptr04668
TNF signaling pathway
ptr04722
Neurotrophin signaling pathway
ptr04723
Retrograde endocannabinoid signaling
ptr04728
Dopaminergic synapse
ptr04750
Inflammatory mediator regulation of TRP channels
ptr04910
Insulin signaling pathway
ptr04912
GnRH signaling pathway
ptr04914
Progesterone-mediated oocyte maturation
ptr04917
Prolactin signaling pathway
ptr04920
Adipocytokine signaling pathway
ptr04926
Relaxin signaling pathway
ptr04930
Type II diabetes mellitus
ptr04931
Insulin resistance
ptr04932
Non-alcoholic fatty liver disease
ptr04933
AGE-RAGE signaling pathway in diabetic complications
ptr04935
Growth hormone synthesis, secretion and action
ptr04936
Alcoholic liver disease
ptr05010
Alzheimer disease
ptr05012
Parkinson disease
ptr05016
Huntington disease
ptr05017
Spinocerebellar ataxia
ptr05020
Prion disease
ptr05022
Pathways of neurodegeneration - multiple diseases
ptr05132
Salmonella infection
ptr05133
Pertussis
ptr05135
Yersinia infection
ptr05142
Chagas disease
ptr05145
Toxoplasmosis
ptr05152
Tuberculosis
ptr05161
Hepatitis B
ptr05162
Measles
ptr05166
Human T-cell leukemia virus 1 infection
ptr05167
Kaposi sarcoma-associated herpesvirus infection
ptr05169
Epstein-Barr virus infection
ptr05170
Human immunodeficiency virus 1 infection
ptr05171
Coronavirus disease - COVID-19
ptr05200
Pathways in cancer
ptr05208
Chemical carcinogenesis - reactive oxygen species
ptr05210
Colorectal cancer
ptr05212
Pancreatic cancer
ptr05231
Choline metabolism in cancer
ptr05415
Diabetic cardiomyopathy
ptr05417
Lipid and atherosclerosis
ptr05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
450445 (MAPK8)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
450445 (MAPK8)
04012 ErbB signaling pathway
450445 (MAPK8)
04014 Ras signaling pathway
450445 (MAPK8)
04310 Wnt signaling pathway
450445 (MAPK8)
04668 TNF signaling pathway
450445 (MAPK8)
04068 FoxO signaling pathway
450445 (MAPK8)
04071 Sphingolipid signaling pathway
450445 (MAPK8)
04024 cAMP signaling pathway
450445 (MAPK8)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
450445 (MAPK8)
04137 Mitophagy - animal
450445 (MAPK8)
09143 Cell growth and death
04210 Apoptosis
450445 (MAPK8)
04215 Apoptosis - multiple species
450445 (MAPK8)
04217 Necroptosis
450445 (MAPK8)
09144 Cellular community - eukaryotes
04510 Focal adhesion
450445 (MAPK8)
04530 Tight junction
450445 (MAPK8)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
450445 (MAPK8)
04621 NOD-like receptor signaling pathway
450445 (MAPK8)
04622 RIG-I-like receptor signaling pathway
450445 (MAPK8)
04625 C-type lectin receptor signaling pathway
450445 (MAPK8)
04660 T cell receptor signaling pathway
450445 (MAPK8)
04658 Th1 and Th2 cell differentiation
450445 (MAPK8)
04659 Th17 cell differentiation
450445 (MAPK8)
04657 IL-17 signaling pathway
450445 (MAPK8)
04664 Fc epsilon RI signaling pathway
450445 (MAPK8)
09152 Endocrine system
04910 Insulin signaling pathway
450445 (MAPK8)
04920 Adipocytokine signaling pathway
450445 (MAPK8)
04912 GnRH signaling pathway
450445 (MAPK8)
04914 Progesterone-mediated oocyte maturation
450445 (MAPK8)
04917 Prolactin signaling pathway
450445 (MAPK8)
04926 Relaxin signaling pathway
450445 (MAPK8)
04935 Growth hormone synthesis, secretion and action
450445 (MAPK8)
09156 Nervous system
04728 Dopaminergic synapse
450445 (MAPK8)
04723 Retrograde endocannabinoid signaling
450445 (MAPK8)
04722 Neurotrophin signaling pathway
450445 (MAPK8)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
450445 (MAPK8)
09158 Development and regeneration
04380 Osteoclast differentiation
450445 (MAPK8)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
450445 (MAPK8)
05208 Chemical carcinogenesis - reactive oxygen species
450445 (MAPK8)
05231 Choline metabolism in cancer
450445 (MAPK8)
09162 Cancer: specific types
05210 Colorectal cancer
450445 (MAPK8)
05212 Pancreatic cancer
450445 (MAPK8)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
450445 (MAPK8)
05170 Human immunodeficiency virus 1 infection
450445 (MAPK8)
05161 Hepatitis B
450445 (MAPK8)
05171 Coronavirus disease - COVID-19
450445 (MAPK8)
05162 Measles
450445 (MAPK8)
05167 Kaposi sarcoma-associated herpesvirus infection
450445 (MAPK8)
05169 Epstein-Barr virus infection
450445 (MAPK8)
09171 Infectious disease: bacterial
05132 Salmonella infection
450445 (MAPK8)
05135 Yersinia infection
450445 (MAPK8)
05133 Pertussis
450445 (MAPK8)
05152 Tuberculosis
450445 (MAPK8)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
450445 (MAPK8)
05142 Chagas disease
450445 (MAPK8)
09164 Neurodegenerative disease
05010 Alzheimer disease
450445 (MAPK8)
05012 Parkinson disease
450445 (MAPK8)
05016 Huntington disease
450445 (MAPK8)
05017 Spinocerebellar ataxia
450445 (MAPK8)
05020 Prion disease
450445 (MAPK8)
05022 Pathways of neurodegeneration - multiple diseases
450445 (MAPK8)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
450445 (MAPK8)
05418 Fluid shear stress and atherosclerosis
450445 (MAPK8)
05415 Diabetic cardiomyopathy
450445 (MAPK8)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
450445 (MAPK8)
04936 Alcoholic liver disease
450445 (MAPK8)
04932 Non-alcoholic fatty liver disease
450445 (MAPK8)
04931 Insulin resistance
450445 (MAPK8)
04933 AGE-RAGE signaling pathway in diabetic complications
450445 (MAPK8)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
450445 (MAPK8)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ptr01001
]
450445 (MAPK8)
Enzymes [BR:
ptr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
450445 (MAPK8)
Protein kinases [BR:
ptr01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
450445 (MAPK8)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Kdo
ABC1
RIO1
Kinase-like
FTA2
APH
DUF530
Motif
Other DBs
NCBI-GeneID:
450445
NCBI-ProteinID:
XP_016773710
Ensembl:
ENSPTRG00000002478
VGNC:
14517
UniProt:
A0A6D2XDJ7
K7CZW7
LinkDB
All DBs
Position
8:60611629..60739614
Genome browser
AA seq
427 aa
AA seq
DB search
MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEASA
GPLGCCR
NT seq
1284 nt
NT seq
+upstream
nt +downstream
nt
atgagcagaagcaagcgtgacaacaatttttatagtgtagagattggagattctacattc
acagtcctgaaacgatatcagaatttaaaacctataggctcaggagctcaaggaatagta
tgtgcagcttatgatgccattcttgaaagaaatgttgcaatcaagaagctaagccgacca
tttcagaatcagactcatgccaagcgggcctacagagagctagttcttatgaaatgtgtt
aatcacaaaaatataattggccttttgaatgttttcacaccacagaaatccctagaagaa
tttcaagatgtttacatagtcatggagctcatggatgcaaatctttgccaagtgattcag
atggagctagatcatgaaagaatgtcctaccttctctatcagatgctgtgtggaatcaag
caccttcattctgctggaattattcatcgggacttaaagcccagtaatatagtagtaaaa
tctgactgcactttgaagattcttgacttcggtctggccaggactgcaggaacgagtttt
atgatgacgccttacgtagtgactcgctactacagagcacccgaggtcatccttggcatg
ggctacaaggaaaacgttgacatttggtcagttgggtgcatcatgggagaaatgatcaaa
ggtggtgttttgttcccaggtacagatcatattgatcagtggaataaagttattgaacag
cttggaacaccatgtcctgaattcatgaagaaactgcaaccaacagtaaggacttacgtt
gaaaacagacctaaatatgctggatatagctttgagaaactcttccctgatgtccttttc
ccagctgactcagaacacaacaaacttaaagccagtcaggcaagggatttgttatccaaa
atgctggtaatagatgcatctaaaaggatctctgtagatgaagctctccaacacccgtac
atcaatgtctggtatgatccttctgaagcagaagctccaccaccaaagatccctgacaag
cagttagatgaaagggaacacacaatagaagagtggaaagaattgatatataaggaagtt
atggacttggaggagagaaccaagaatggagttatacgggggcagccctctcctttaggt
gcagcagtgatcaatggctctcagcatccatcgtcatcgtcgtctgtcaatgatgtgtct
tcaatgtcaacagatccgactttggcctctgatacagacagcagtctagaagcatcagct
gggcctctgggctgctgtagatga
Pan troglodytes (chimpanzee): 461358
Help
Entry
461358 CDS
T01005
Symbol
MAPK10
Name
(RefSeq) mitogen-activated protein kinase 10 isoform X1
KO
K04440
mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:
2.7.11.24
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr01522
Endocrine resistance
ptr04010
MAPK signaling pathway
ptr04012
ErbB signaling pathway
ptr04014
Ras signaling pathway
ptr04024
cAMP signaling pathway
ptr04068
FoxO signaling pathway
ptr04071
Sphingolipid signaling pathway
ptr04137
Mitophagy - animal
ptr04140
Autophagy - animal
ptr04141
Protein processing in endoplasmic reticulum
ptr04210
Apoptosis
ptr04215
Apoptosis - multiple species
ptr04217
Necroptosis
ptr04310
Wnt signaling pathway
ptr04380
Osteoclast differentiation
ptr04510
Focal adhesion
ptr04530
Tight junction
ptr04620
Toll-like receptor signaling pathway
ptr04621
NOD-like receptor signaling pathway
ptr04622
RIG-I-like receptor signaling pathway
ptr04625
C-type lectin receptor signaling pathway
ptr04657
IL-17 signaling pathway
ptr04658
Th1 and Th2 cell differentiation
ptr04659
Th17 cell differentiation
ptr04660
T cell receptor signaling pathway
ptr04664
Fc epsilon RI signaling pathway
ptr04668
TNF signaling pathway
ptr04722
Neurotrophin signaling pathway
ptr04723
Retrograde endocannabinoid signaling
ptr04728
Dopaminergic synapse
ptr04750
Inflammatory mediator regulation of TRP channels
ptr04910
Insulin signaling pathway
ptr04912
GnRH signaling pathway
ptr04914
Progesterone-mediated oocyte maturation
ptr04917
Prolactin signaling pathway
ptr04920
Adipocytokine signaling pathway
ptr04926
Relaxin signaling pathway
ptr04930
Type II diabetes mellitus
ptr04931
Insulin resistance
ptr04932
Non-alcoholic fatty liver disease
ptr04933
AGE-RAGE signaling pathway in diabetic complications
ptr04935
Growth hormone synthesis, secretion and action
ptr04936
Alcoholic liver disease
ptr05010
Alzheimer disease
ptr05012
Parkinson disease
ptr05016
Huntington disease
ptr05017
Spinocerebellar ataxia
ptr05020
Prion disease
ptr05022
Pathways of neurodegeneration - multiple diseases
ptr05132
Salmonella infection
ptr05133
Pertussis
ptr05135
Yersinia infection
ptr05142
Chagas disease
ptr05145
Toxoplasmosis
ptr05152
Tuberculosis
ptr05161
Hepatitis B
ptr05162
Measles
ptr05166
Human T-cell leukemia virus 1 infection
ptr05167
Kaposi sarcoma-associated herpesvirus infection
ptr05169
Epstein-Barr virus infection
ptr05170
Human immunodeficiency virus 1 infection
ptr05171
Coronavirus disease - COVID-19
ptr05200
Pathways in cancer
ptr05208
Chemical carcinogenesis - reactive oxygen species
ptr05210
Colorectal cancer
ptr05212
Pancreatic cancer
ptr05231
Choline metabolism in cancer
ptr05415
Diabetic cardiomyopathy
ptr05417
Lipid and atherosclerosis
ptr05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
461358 (MAPK10)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
461358 (MAPK10)
04012 ErbB signaling pathway
461358 (MAPK10)
04014 Ras signaling pathway
461358 (MAPK10)
04310 Wnt signaling pathway
461358 (MAPK10)
04668 TNF signaling pathway
461358 (MAPK10)
04068 FoxO signaling pathway
461358 (MAPK10)
04071 Sphingolipid signaling pathway
461358 (MAPK10)
04024 cAMP signaling pathway
461358 (MAPK10)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
461358 (MAPK10)
04137 Mitophagy - animal
461358 (MAPK10)
09143 Cell growth and death
04210 Apoptosis
461358 (MAPK10)
04215 Apoptosis - multiple species
461358 (MAPK10)
04217 Necroptosis
461358 (MAPK10)
09144 Cellular community - eukaryotes
04510 Focal adhesion
461358 (MAPK10)
04530 Tight junction
461358 (MAPK10)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
461358 (MAPK10)
04621 NOD-like receptor signaling pathway
461358 (MAPK10)
04622 RIG-I-like receptor signaling pathway
461358 (MAPK10)
04625 C-type lectin receptor signaling pathway
461358 (MAPK10)
04660 T cell receptor signaling pathway
461358 (MAPK10)
04658 Th1 and Th2 cell differentiation
461358 (MAPK10)
04659 Th17 cell differentiation
461358 (MAPK10)
04657 IL-17 signaling pathway
461358 (MAPK10)
04664 Fc epsilon RI signaling pathway
461358 (MAPK10)
09152 Endocrine system
04910 Insulin signaling pathway
461358 (MAPK10)
04920 Adipocytokine signaling pathway
461358 (MAPK10)
04912 GnRH signaling pathway
461358 (MAPK10)
04914 Progesterone-mediated oocyte maturation
461358 (MAPK10)
04917 Prolactin signaling pathway
461358 (MAPK10)
04926 Relaxin signaling pathway
461358 (MAPK10)
04935 Growth hormone synthesis, secretion and action
461358 (MAPK10)
09156 Nervous system
04728 Dopaminergic synapse
461358 (MAPK10)
04723 Retrograde endocannabinoid signaling
461358 (MAPK10)
04722 Neurotrophin signaling pathway
461358 (MAPK10)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
461358 (MAPK10)
09158 Development and regeneration
04380 Osteoclast differentiation
461358 (MAPK10)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
461358 (MAPK10)
05208 Chemical carcinogenesis - reactive oxygen species
461358 (MAPK10)
05231 Choline metabolism in cancer
461358 (MAPK10)
09162 Cancer: specific types
05210 Colorectal cancer
461358 (MAPK10)
05212 Pancreatic cancer
461358 (MAPK10)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
461358 (MAPK10)
05170 Human immunodeficiency virus 1 infection
461358 (MAPK10)
05161 Hepatitis B
461358 (MAPK10)
05171 Coronavirus disease - COVID-19
461358 (MAPK10)
05162 Measles
461358 (MAPK10)
05167 Kaposi sarcoma-associated herpesvirus infection
461358 (MAPK10)
05169 Epstein-Barr virus infection
461358 (MAPK10)
09171 Infectious disease: bacterial
05132 Salmonella infection
461358 (MAPK10)
05135 Yersinia infection
461358 (MAPK10)
05133 Pertussis
461358 (MAPK10)
05152 Tuberculosis
461358 (MAPK10)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
461358 (MAPK10)
05142 Chagas disease
461358 (MAPK10)
09164 Neurodegenerative disease
05010 Alzheimer disease
461358 (MAPK10)
05012 Parkinson disease
461358 (MAPK10)
05016 Huntington disease
461358 (MAPK10)
05017 Spinocerebellar ataxia
461358 (MAPK10)
05020 Prion disease
461358 (MAPK10)
05022 Pathways of neurodegeneration - multiple diseases
461358 (MAPK10)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
461358 (MAPK10)
05418 Fluid shear stress and atherosclerosis
461358 (MAPK10)
05415 Diabetic cardiomyopathy
461358 (MAPK10)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
461358 (MAPK10)
04936 Alcoholic liver disease
461358 (MAPK10)
04932 Non-alcoholic fatty liver disease
461358 (MAPK10)
04931 Insulin resistance
461358 (MAPK10)
04933 AGE-RAGE signaling pathway in diabetic complications
461358 (MAPK10)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
461358 (MAPK10)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ptr01001
]
461358 (MAPK10)
Enzymes [BR:
ptr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
461358 (MAPK10)
Protein kinases [BR:
ptr01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
461358 (MAPK10)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Kdo
ABC1
RIO1
Kinase-like
APH
FTA2
Motif
Other DBs
NCBI-GeneID:
461358
NCBI-ProteinID:
XP_016807318
Ensembl:
ENSPTRG00000016244
VGNC:
7423
UniProt:
A0A2J8L2H3
LinkDB
All DBs
Position
3:complement(87407621..87975145)
Genome browser
AA seq
464 aa
AA seq
DB search
MSLHFLYYCSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTV
LKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH
KNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHL
HSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY
KENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVEN
RPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYIN
VWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAA
VNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR
NT seq
1395 nt
NT seq
+upstream
nt +downstream
nt
atgagcctccatttcttatactactgcagtgaaccaacattggatgtgaaaattgccttt
tgtcagggattcgataaacaagtggatgtgtcatatattgccaaacattacaacatgagc
aaaagcaaagttgacaaccagttctacagtgtggaagtgggagactcaaccttcacagtt
ctcaagcgctaccagaatctaaagcctattggctctggggctcagggcatagtttgtgcg
gcgtatgatgctgtccttgacagaaatgtggccattaagaagctcagcagaccctttcag
aaccaaacacatgccaagagagcgtaccgggagctggtcctcatgaagtgtgtgaaccat
aaaaacattattagtttattaaatgtcttcacaccccagaaaacgctggaggagttccaa
gatgtttacttagtaatggaactgatggatgccaacttatgtcaagtgattcagatggaa
ttagaccatgagcgaatgtcttacctgctgtaccaaatgttgtgtggcattaagcacctc
cattctgctggaattattcacagggatttaaaaccaagtaacattgtagtcaagtctgat
tgcacattgaaaatcctggactttggactggccaggacagcaggcacaagcttcatgatg
actccatatgtggtgacacgttattacagagcccctgaggtcatcctggggatgggctac
aaggagaacgtggatatatggtctgtgggatgcattatgggagaaatggttcgccacaaa
atcctctttccaggaagggactatattgaccagtggaataaggtaattgaacaactagga
acaccatgtccagaattcatgaagaaattgcaacccacagtaagaaactatgtggagaat
cggcccaagtatgcgggactcaccttccccaaactcttcccagattccctcttcccagcg
gactccgagcacaataaactcaaagccagccaagccagggacttgttgtcaaagatgcta
gtgattgacccagcaaaaagaatatcagtggacgacgccttacagcatccctacatcaac
gtctggtatgacccagccgaagtggaggcgcctccacctcagatatatgacaagcagttg
gatgaaagagaacacacaatcgaagaatggaaagaacttatctacaaggaagtaatgaat
tcagaagaaaagactaaaaatggtgtagtaaaaggacagccttctccttcaggtgcagca
gtgaacagcagtgagagtctccctccatcctcgtctgtcaatgacatctcctccatgtcc
accgaccagaccctggcatctgacactgacagcagcctggaagcctcggcaggacccctg
ggttgttgcaggtga
Pan troglodytes (chimpanzee): 462336
Help
Entry
462336 CDS
T01005
Symbol
MAPK9
Name
(RefSeq) mitogen-activated protein kinase 9 isoform X2
KO
K04440
mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:
2.7.11.24
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr01522
Endocrine resistance
ptr04010
MAPK signaling pathway
ptr04012
ErbB signaling pathway
ptr04014
Ras signaling pathway
ptr04024
cAMP signaling pathway
ptr04068
FoxO signaling pathway
ptr04071
Sphingolipid signaling pathway
ptr04137
Mitophagy - animal
ptr04140
Autophagy - animal
ptr04141
Protein processing in endoplasmic reticulum
ptr04210
Apoptosis
ptr04215
Apoptosis - multiple species
ptr04217
Necroptosis
ptr04310
Wnt signaling pathway
ptr04380
Osteoclast differentiation
ptr04510
Focal adhesion
ptr04530
Tight junction
ptr04620
Toll-like receptor signaling pathway
ptr04621
NOD-like receptor signaling pathway
ptr04622
RIG-I-like receptor signaling pathway
ptr04625
C-type lectin receptor signaling pathway
ptr04657
IL-17 signaling pathway
ptr04658
Th1 and Th2 cell differentiation
ptr04659
Th17 cell differentiation
ptr04660
T cell receptor signaling pathway
ptr04664
Fc epsilon RI signaling pathway
ptr04668
TNF signaling pathway
ptr04722
Neurotrophin signaling pathway
ptr04723
Retrograde endocannabinoid signaling
ptr04728
Dopaminergic synapse
ptr04750
Inflammatory mediator regulation of TRP channels
ptr04910
Insulin signaling pathway
ptr04912
GnRH signaling pathway
ptr04914
Progesterone-mediated oocyte maturation
ptr04917
Prolactin signaling pathway
ptr04920
Adipocytokine signaling pathway
ptr04926
Relaxin signaling pathway
ptr04930
Type II diabetes mellitus
ptr04931
Insulin resistance
ptr04932
Non-alcoholic fatty liver disease
ptr04933
AGE-RAGE signaling pathway in diabetic complications
ptr04935
Growth hormone synthesis, secretion and action
ptr04936
Alcoholic liver disease
ptr05010
Alzheimer disease
ptr05012
Parkinson disease
ptr05016
Huntington disease
ptr05017
Spinocerebellar ataxia
ptr05020
Prion disease
ptr05022
Pathways of neurodegeneration - multiple diseases
ptr05132
Salmonella infection
ptr05133
Pertussis
ptr05135
Yersinia infection
ptr05142
Chagas disease
ptr05145
Toxoplasmosis
ptr05152
Tuberculosis
ptr05161
Hepatitis B
ptr05162
Measles
ptr05166
Human T-cell leukemia virus 1 infection
ptr05167
Kaposi sarcoma-associated herpesvirus infection
ptr05169
Epstein-Barr virus infection
ptr05170
Human immunodeficiency virus 1 infection
ptr05171
Coronavirus disease - COVID-19
ptr05200
Pathways in cancer
ptr05208
Chemical carcinogenesis - reactive oxygen species
ptr05210
Colorectal cancer
ptr05212
Pancreatic cancer
ptr05231
Choline metabolism in cancer
ptr05415
Diabetic cardiomyopathy
ptr05417
Lipid and atherosclerosis
ptr05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
462336 (MAPK9)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
462336 (MAPK9)
04012 ErbB signaling pathway
462336 (MAPK9)
04014 Ras signaling pathway
462336 (MAPK9)
04310 Wnt signaling pathway
462336 (MAPK9)
04668 TNF signaling pathway
462336 (MAPK9)
04068 FoxO signaling pathway
462336 (MAPK9)
04071 Sphingolipid signaling pathway
462336 (MAPK9)
04024 cAMP signaling pathway
462336 (MAPK9)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
462336 (MAPK9)
04137 Mitophagy - animal
462336 (MAPK9)
09143 Cell growth and death
04210 Apoptosis
462336 (MAPK9)
04215 Apoptosis - multiple species
462336 (MAPK9)
04217 Necroptosis
462336 (MAPK9)
09144 Cellular community - eukaryotes
04510 Focal adhesion
462336 (MAPK9)
04530 Tight junction
462336 (MAPK9)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
462336 (MAPK9)
04621 NOD-like receptor signaling pathway
462336 (MAPK9)
04622 RIG-I-like receptor signaling pathway
462336 (MAPK9)
04625 C-type lectin receptor signaling pathway
462336 (MAPK9)
04660 T cell receptor signaling pathway
462336 (MAPK9)
04658 Th1 and Th2 cell differentiation
462336 (MAPK9)
04659 Th17 cell differentiation
462336 (MAPK9)
04657 IL-17 signaling pathway
462336 (MAPK9)
04664 Fc epsilon RI signaling pathway
462336 (MAPK9)
09152 Endocrine system
04910 Insulin signaling pathway
462336 (MAPK9)
04920 Adipocytokine signaling pathway
462336 (MAPK9)
04912 GnRH signaling pathway
462336 (MAPK9)
04914 Progesterone-mediated oocyte maturation
462336 (MAPK9)
04917 Prolactin signaling pathway
462336 (MAPK9)
04926 Relaxin signaling pathway
462336 (MAPK9)
04935 Growth hormone synthesis, secretion and action
462336 (MAPK9)
09156 Nervous system
04728 Dopaminergic synapse
462336 (MAPK9)
04723 Retrograde endocannabinoid signaling
462336 (MAPK9)
04722 Neurotrophin signaling pathway
462336 (MAPK9)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
462336 (MAPK9)
09158 Development and regeneration
04380 Osteoclast differentiation
462336 (MAPK9)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
462336 (MAPK9)
05208 Chemical carcinogenesis - reactive oxygen species
462336 (MAPK9)
05231 Choline metabolism in cancer
462336 (MAPK9)
09162 Cancer: specific types
05210 Colorectal cancer
462336 (MAPK9)
05212 Pancreatic cancer
462336 (MAPK9)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
462336 (MAPK9)
05170 Human immunodeficiency virus 1 infection
462336 (MAPK9)
05161 Hepatitis B
462336 (MAPK9)
05171 Coronavirus disease - COVID-19
462336 (MAPK9)
05162 Measles
462336 (MAPK9)
05167 Kaposi sarcoma-associated herpesvirus infection
462336 (MAPK9)
05169 Epstein-Barr virus infection
462336 (MAPK9)
09171 Infectious disease: bacterial
05132 Salmonella infection
462336 (MAPK9)
05135 Yersinia infection
462336 (MAPK9)
05133 Pertussis
462336 (MAPK9)
05152 Tuberculosis
462336 (MAPK9)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
462336 (MAPK9)
05142 Chagas disease
462336 (MAPK9)
09164 Neurodegenerative disease
05010 Alzheimer disease
462336 (MAPK9)
05012 Parkinson disease
462336 (MAPK9)
05016 Huntington disease
462336 (MAPK9)
05017 Spinocerebellar ataxia
462336 (MAPK9)
05020 Prion disease
462336 (MAPK9)
05022 Pathways of neurodegeneration - multiple diseases
462336 (MAPK9)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
462336 (MAPK9)
05418 Fluid shear stress and atherosclerosis
462336 (MAPK9)
05415 Diabetic cardiomyopathy
462336 (MAPK9)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
462336 (MAPK9)
04936 Alcoholic liver disease
462336 (MAPK9)
04932 Non-alcoholic fatty liver disease
462336 (MAPK9)
04931 Insulin resistance
462336 (MAPK9)
04933 AGE-RAGE signaling pathway in diabetic complications
462336 (MAPK9)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
462336 (MAPK9)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ptr01001
]
462336 (MAPK9)
Enzymes [BR:
ptr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
462336 (MAPK9)
Protein kinases [BR:
ptr01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
462336 (MAPK9)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
Kdo
RIO1
Kinase-like
APH
FTA2
Motif
Other DBs
NCBI-GeneID:
462336
NCBI-ProteinID:
XP_001154742
Ensembl:
ENSPTRG00000017633
VGNC:
8627
UniProt:
K7B4X0
A0A803KIS4
LinkDB
All DBs
Position
4:complement(177724443..177782662)
Genome browser
AA seq
424 aa
AA seq
DB search
MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP
FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQ
LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK
MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV
MDWEERSKNGVVKDQPSDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPL
EGCR
NT seq
1275 nt
NT seq
+upstream
nt +downstream
nt
atgagtgacagtaaatgtgacagtcagttttacagtgtgcaagtggcagactcaaccttc
actgtcctaaaacgttaccagcagctgaaaccaattggctctggggcccaagggattgtt
tgtgctgcatttgatacagttcttgggataaatgttgcagtcaagaaactaagccgtcct
tttcagaaccaaactcatgcaaagagagcttatcgtgaactcgtcctcttaaaatgtgtc
aatcataaaaatataattagtttgttaaatgtgtttacaccacaaaaaactctagaagaa
tttcaagatgtgtatttggttatggaattaatggatgctaacttatgtcaggttattcac
atggagctggatcatgaaagaatgtcctaccttctttaccagatgctttgtggtattaaa
catctgcattcagctggtataattcatagagatttaaagcctagcaacattgttgtgaaa
tcagactgcaccctgaagatccttgactttggcctggcccggacagcgtgcactaacttc
atgatgaccccttatgtggtgacacggtactaccgggcgcccgaagtcatcctgggtatg
ggctacaaagagaacgtggacatctggtctgtcgggtgcatcatggcagaaatggtcctc
cataaagtcctgttcccgggaagagactatattgatcagtggaataaagttattgagcag
ctgggaacaccatcagcagagttcatgaagaaacttcagccaactgtgaggaattatgtc
gaaaacagaccaaagtatcctggaatcaaattcgaagaactctttccagattggatattc
ccatcagaatctgagcgagacaaaataaaaacaagtcaagccagagatctgttatcaaaa
atgttagtgattgatcctgacaagcggatctctgtagatgaagctctgcgtcacccatac
atcactgtttggtatgaccctgccgaagcagaagccccaccacctcaaatttatgatgcc
cagttggaagaaagagaacatgcaattgaagaatggaaagagctaatttacaaagaagtc
atggattgggaagaaagaagcaagaatggtgttgtaaaagatcagccttcagatgcagca
gtaagtagcaacgccactccttctcagtcttcatcgatcaatgacatttcatccatgtcc
actgagcagacgctggcctcagacacagacagcagtcttgatgcctcgacgggacccctt
gaaggctgtcgatga
DBGET
integrated database retrieval system
