KEGG   REACTION: R05188Help
Entry
R05188                      Reaction                               

Name
acyl-CoA:malonyl-CoA C-acyltransferase(decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing)
Definition
Acetyl-CoA + n Malonyl-CoA + 2n NADPH + 2n H+ <=> Long-chain fatty acid + n CO2 + 2n NADP+ + (n+1) CoA + n H2O
Equation
C00024 + n C00083 + 2n C00005 + 2n C00080 <=> C00638 + n C00011 + 2n C00006 + (n+1) C00010 + n C00001
Comment
multi-step reaction (see map00061)
Reaction class
RC00001  C00005_C00006
RC00004  C00010_C00024  C00010_C00083
Enzyme
Pathway
rn00061  Fatty acid biosynthesis
Orthology
K00665  fatty acid synthase, animal type [EC:2.3.1.85]
Other DBs
RHEA: 14996
LinkDB All DBs

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