Rattus norvegicus (rat): 24239
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Entry
24239 CDS
T01003
Gene name
Cacna1c, RATIVS302
Definition
(RefSeq) calcium voltage-gated channel subunit alpha1 C
KO
K04850
voltage-dependent calcium channel L type alpha-1C
Organism
rno
Rattus norvegicus (rat)
Pathway
rno04010
MAPK signaling pathway
rno04020
Calcium signaling pathway
rno04022
cGMP-PKG signaling pathway
rno04024
cAMP signaling pathway
rno04260
Cardiac muscle contraction
rno04261
Adrenergic signaling in cardiomyocytes
rno04270
Vascular smooth muscle contraction
rno04713
Circadian entrainment
rno04720
Long-term potentiation
rno04723
Retrograde endocannabinoid signaling
rno04724
Glutamatergic synapse
rno04725
Cholinergic synapse
rno04726
Serotonergic synapse
rno04727
GABAergic synapse
rno04728
Dopaminergic synapse
rno04742
Taste transduction
rno04911
Insulin secretion
rno04912
GnRH signaling pathway
rno04921
Oxytocin signaling pathway
rno04924
Renin secretion
rno04925
Aldosterone synthesis and secretion
rno04927
Cortisol synthesis and secretion
rno04929
GnRH secretion
rno04930
Type II diabetes mellitus
rno04934
Cushing syndrome
rno04935
Growth hormone synthesis, secretion and action
rno05010
Alzheimer disease
rno05020
Prion disease
rno05022
Pathways of neurodegeneration - multiple diseases
rno05031
Amphetamine addiction
rno05410
Hypertrophic cardiomyopathy
rno05412
Arrhythmogenic right ventricular cardiomyopathy
rno05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
24239 (Cacna1c)
04020 Calcium signaling pathway
24239 (Cacna1c)
04024 cAMP signaling pathway
24239 (Cacna1c)
04022 cGMP-PKG signaling pathway
24239 (Cacna1c)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
24239 (Cacna1c)
04929 GnRH secretion
24239 (Cacna1c)
04912 GnRH signaling pathway
24239 (Cacna1c)
04921 Oxytocin signaling pathway
24239 (Cacna1c)
04935 Growth hormone synthesis, secretion and action
24239 (Cacna1c)
04924 Renin secretion
24239 (Cacna1c)
04925 Aldosterone synthesis and secretion
24239 (Cacna1c)
04927 Cortisol synthesis and secretion
24239 (Cacna1c)
09153 Circulatory system
04260 Cardiac muscle contraction
24239 (Cacna1c)
04261 Adrenergic signaling in cardiomyocytes
24239 (Cacna1c)
04270 Vascular smooth muscle contraction
24239 (Cacna1c)
09156 Nervous system
04724 Glutamatergic synapse
24239 (Cacna1c)
04727 GABAergic synapse
24239 (Cacna1c)
04725 Cholinergic synapse
24239 (Cacna1c)
04728 Dopaminergic synapse
24239 (Cacna1c)
04726 Serotonergic synapse
24239 (Cacna1c)
04720 Long-term potentiation
24239 (Cacna1c)
04723 Retrograde endocannabinoid signaling
24239 (Cacna1c)
09157 Sensory system
04742 Taste transduction
24239 (Cacna1c)
09159 Environmental adaptation
04713 Circadian entrainment
24239 (Cacna1c)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
24239 (Cacna1c)
05020 Prion disease
24239 (Cacna1c)
05022 Pathways of neurodegeneration - multiple diseases
24239 (Cacna1c)
09165 Substance dependence
05031 Amphetamine addiction
24239 (Cacna1c)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
24239 (Cacna1c)
05412 Arrhythmogenic right ventricular cardiomyopathy
24239 (Cacna1c)
05414 Dilated cardiomyopathy
24239 (Cacna1c)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
24239 (Cacna1c)
04934 Cushing syndrome
24239 (Cacna1c)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
rno04040
]
24239 (Cacna1c)
Ion channels [BR:
rno04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
24239 (Cacna1c)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ion_trans
CAC1F_C
GPHH
Ca_chan_IQ
PKD_channel
Etmic-2
DUF4834
Motif
Other DBs
NCBI-GeneID:
24239
NCBI-ProteinID:
NP_036649
RGD:
2245
Ensembl:
ENSRNOG00000007090
UniProt:
P22002
Q71QJ6
A0SLC4
LinkDB
All DBs
Structure
PDB:
1VYT
Thumbnails
Position
4q42
AA seq
2170 aa
AA seq
DB search
MIRAFAQPSTPPYQPLSSCLSEDTERKFKGKVVHEAQLNCFYISPGGSNYGSPRPAHANM
NANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPK
KQGGTTATRPPRALLCLTLKNPIRRACISIVEWKSFEIIILLTIFANCVALAIYIPFPED
DSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSA
ILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLH
IALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIIDVPAEEDPSPCALETGHGRQCQNGT
VCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVI
FGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPE
NEDEGMDEDKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWN
RFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAE
MLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKI
TRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFD
NFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLA
IAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEVMEKPAVEESKEEKIELKSIT
ADGESPPTTKINMDDLQPSENEDKSPHSNPDTAGEEDEEEPEMPVGPRPRPLSELHLKEK
AVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRN
HILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSA
INVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQL
FKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFT
VSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQ
EQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLIL
LNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALI
VVGSIVDIAITEVHPAEHTQCSPSMSAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLL
WTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLF
RCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINL
FVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGF
GKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIK
KIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALS
LQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYY
QSDSRSNFPQTFATQRPLHINKTGNNQADTESPSHEKLVDSTFTPSSYSSTGSNANINNA
NNTALGRFPHPAGYSSTVSTVEGHGPPLSPAVRVQEAAWKLSSKRCHSRESQGATVSQDM
FPDETRSSVRLSEEVEYCSEPSLLSTDILSYQDDENRQLTCLEEDKREIQPSPKRSFLRS
ASLGRRASFHLECLKRQKDQGGDISQKTALPLHLVHHQALAVAGLSPLLQRSHSPSTFPR
PRPTPPVTPGSRGRPLQPIPTLRLEGAESSEKLNSSFPSIHCSSWSEETTACSGGSSMAR
RARPVSLTVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDM
TIEEMENAADNILSGGAQQSPNGTLLPFVNCRDPGQDRAVVPEDESCVYALGRGRSEEAL
PDSRSYVSNL
NT seq
6513 nt
NT seq
+upstream
nt +downstream
nt
atgattcgggccttcgctcagccatccacacccccataccagccgctctccagttgcctg
tctgaggacacagagaggaagttcaagggcaaggtggtacacgaagctcaactcaactgt
ttctacatttctcctggaggttccaactatgggagcccacgcccagctcatgccaacatg
aatgccaatgcagctgcaggacttgcccccgagcacatccctactccaggggcagcactg
tcctggcaggcagccatcgatgccgcccggcaggccaagttaatgggcagtgctggcaat
gcgaccatctctaccgtcagttccacacagcggaagcggcagcagtatgggaaacccaag
aagcaggggggcacaactgccacacggccgccccgggctctgctctgcctgactctgaag
aaccccatcaggagggcatgcatcagcattgttgaatggaaatcatttgaaataattatt
ttattgacgatttttgccaattgtgtggccttagcaatctatattccctttccggaagat
gactccaacgccaccaactccaacctggaacgggtggagtatctcttcctcatcattttt
accgtggaagcatttttaaaagtgattgcctacggactactcttccaccccaacgcttac
ctccgcaacggttggaatttactagattttataatcgtggttgtagggctttttagtgca
attttagaacaagcaaccaaagctgacggggccaacgctctgggagggaaaggagcggga
ttcgatgtgaaggcactgagagctttccgtgtgcttcgtcccctgcggctggtgtctgga
gtcccaagtctccaggtggtcctgaactccatcatcaaggccatggtgcccctgctgcac
attgccctcctcgtgctcttcgtcatcatcatctatgccattatcggcctggagctcttc
atggggaagatgcacaagacctgctacaaccaggagggcataatagatgttccagcggaa
gaggatccctccccttgtgctttggagacaggccatgggcgacagtgtcagaacgggacc
gtgtgcaagcccgggtgggatgggcccaagcacggcatcaccaacttcgacaacttcgcc
ttcgccatgctgacggtgttccagtgtatcaccatggagggctggacagacgtgctgtac
tggatgcaagacgctatgggctatgagttgccctgggtgtattttgtcagtctggtcatc
tttggatcctttttcgttctaaatctggttctcggtgttttgagcggagagttttccaaa
gagagggagaaagccaaagctcgaggagacttccagaagcttcgtgagaagcagcagcta
gaagaagatctcaaaggctacctggactggatcacccaggcggaagacatagaccctgag
aatgaggacgagggcatggatgaagacaaaccccgaaacatgagcatgcccacaagtgag
actgagtctgtcaacaccgaaaacgtggctggaggtgacatcgagggtgaaaactgtgga
gcccggcttgcccaccggatctccaaatccaagttcagccgctactggcgccggtggaat
agattctgcagaagaaagtgccgtgccgcagttaagtccaatgtcttctactggctggtg
atcttcctggtgttcctcaacaccctcaccattgcctccgaacactacaaccagcctcat
tggctcacagaagtgcaagacacggccaacaaggccctcctggcccttttcacggcagaa
atgctcctgaagatgtacagcctgggtctgcaggcctactttgtatccctcttcaaccgc
tttgactgtttcattgtgtgcgggggcatcctggagaccatcctggtggagacgaagatc
atgtcgcccctgggcatctctgtgctgagatgtgtgcggctgctcaggattttcaagatc
accaggtactggaactccctgagcaacctcgtggcgtccttgctgaactcagtgcgctcc
atcgcctccctgctgctactcctcttcctcttcatcatcatcttctccctcctggggatg
cagctgtttggtggaaagttcaactttgatgagatgcagacccgtaggagcacgtttgat
aacttcccacagtctctcctcactgtgtttcagatcctgaccggggaggactggaattcg
gtgatgtatgatgggatcatggcttatggcggcccctcttttccagggatgttagtctgt
atttacttcatcatcctcttcatctgtggaaattatatcctactgaatgtgttcttggcc
attgcggtggacaacctggctgatgcggagagcctgacctctgcccaaaaagaggaagaa
gaagagaaggagagaaagaagctggccaggactgccagcccagaaaagaaacaggaggtg
atggagaaaccagcagtagaggagagcaaagaggagaaaattgagctgaagtccattaca
gcagatggagaatccccacccactaccaagatcaacatggatgacctccagcccagtgaa
aatgaggacaagagtccccactccaacccagacactgcaggtgaagaggatgaggaggag
cccgagatgcctgtgggcccacgcccccggcccctgtctgagctgcaccttaaggaaaag
gcagtccccatgccggaagccagtgcatttttcatcttcagcccaaacaacaggttccgc
ctgcagtgccaccgcattgtcaatgacacgatcttcaccaacctcatcctcttcttcatt
ctgctcagtagcatctccctggcggctgaggaccccgtccagcacacctccttcaggaac
cacattctgttttattttgacattgtttttaccaccattttcaccattgaaattgctcta
aagatgactgcttacggggctttcctgcacaagggctctttctgccgaaattacttcaat
atcctggacctgctggtggttagcgtgtccctcatctcctttggcattcagtccagcgcg
atcaacgttgtgaagattttaagagtgcttcgtgtcctcaggcccctgagggccatcaac
agggccaaggggctaaagcacgtcgttcagtgtgtgtttgtggccatccggaccattgga
aacattgtaattgtcaccactctgctgcagttcatgttcgcctgcattggggtccagctc
ttcaagggaaagctctatacctgttcggatagttccaaacagacggaggcagaatgcaag
ggtaactatataacatacaaagacggagaagttgaccaccccattatccagcctcgaagt
tgggagaacagcaagttcgactttgacaatgttctggcagccatgatggccctctttacc
gtctccaccttcgaggggtggccagagctgctgtaccgctccattgactcccacacagaa
gacaagggtcccatctacaactatcgtgtggagatctccatcttcttcatcatctacatc
atcatcattgccttcttcatgatgaacatcttcgtgggtttcgtcattgtcaccttccag
gagcagggggaacaagaatacaagaactgtgagctggacaagaaccagagacaatgtgtg
gaatatgccctcaaggcccgacccttgcgaaggtacatccccaagaaccagcaccagtac
aaagtgtggtacgtggtcaactccacctacttcgagtatctgatgttcgtcctcatcctg
ctcaacaccatctgcctggccatgcagcactacggccagagctgcctcttcaaaatcgcc
atgaatatactcaacatgcttttcactggcctcttcacggtggagatgatcctgaagctc
attgccttcaaacccaagcactatttctgtgatgcatggaatacatttgacgccttgatt
gttgtgggtagcattgttgatatagcaatcaccgaggtacacccagctgaacatacccaa
tgctctccctctatgagtgcagaggagaactcccgcatctccatcaccttcttccgcctc
ttccgggtcatgcgcctggtgaagctgctgagccgaggggaaggcatccggaccctgctg
tggaccttcatcaagtccttccaggccctgccctatgtggcccttttgattgtgatgctg
ttctttatctatgcagtgattgggatgcaggtatttgggaagattgccctgaatgacacc
acagagatcaatcggaacaacaacttccagacgttccctcaggctgtgctactgctcttc
aggtgcgccactggggaggcctggcaggatatcatgctagcctgtatgccaggcaagaag
tgtgctccagagtctgagcccagcaacagcacggaaggggagacaccctgtggcagcagt
ttcgctgtcttctacttcatcagcttctacatgctctgtgccttcctgatcatcaacctc
tttgtagctgttatcatggacaactttgactacctgactagggattggtctatccttggt
ccccatcacctggatgaattcaagagaatctgggccgaatatgaccctgaagccaagggt
cggatcaaacacttggatgtggtgaccctcctccgtcgaattcagcccccactgggtttt
gggaagttgtgtcctcaccgtgtggcctgcaaacgcctggtgtccatgaacatgcctctg
aacagtgatgggacggtcatgttcaatgctacactgtttgcccttgtcaggacagccctg
aggatcaaaacagaagggaacctagagcaagccaatgaggagctgagagccatcatcaag
aaaatctggaagaggaccagcatgaagctgttggaccaggtggtgccccctgcaggtgat
gacgaggtcacagtgggcaagttctatgccaccttcctgatccaagagtacttcaggaaa
ttcaagaagcgaaaagagcaggggctggtcggcaagccctcgcagaggaatgcactgtct
ctgcaggctggcttacgcaccttgcatgacattgggcctgagatccggagagccatctct
ggggatctgacggctgaggaggagctggacaaggctatgaaggaggcagtgtctgctgcc
tccgaagacgacatcttcaggagggctggaggcctgtttggcaaccacgtcagctactac
cagagtgacagcaggagcaacttccctcagacgtttgccacccaacgcccactgcacatc
aacaagacagggaacaaccaagcggacaccgaatcaccgtcccatgagaagctggtggac
tccactttcacccccagcagctactcatccacgggctccaatgccaacatcaacaatgcc
aacaacactgccctgggccgcttcccccaccctgctggctactccagcacggtcagcact
gtggagggccatgggcctcccttgtcccctgctgtccgggtacaggaggcagcatggaaa
ctcagctctaagaggtgccactcccgagagagccagggggccacggtgagtcaggatatg
tttccagatgagacccgcagcagcgtgaggctgagcgaagaagttgagtactgcagtgag
cccagcctgctctccacagatatactctcctaccaggacgatgaaaaccgacaactgacc
tgtctagaggaggacaagagggagatccagccatctccgaagaggagtttccttcgctct
gcctctctaggtcgaagggcctccttccatctggaatgtctaaagcgacaaaaggatcaa
gggggagacatctctcagaagacagccttgcccttgcatctggttcatcaccaggcattg
gcagtggcaggcttgagccccctcctgcagagaagccattctccttccacgttccccagg
ccacgccccacgccccctgtcactccaggcagccggggcaggcccctacagcccatccct
accctgcggctggagggggcggagtccagtgagaaactcaacagcagcttcccgtccatc
cactgcagctcctggtcagaggagaccacagcctgtagtgggggcagcagcatggcccgg
agagcccggcccgtctccctcaccgtgcccagccaggctggagctccaggcagacagttc
cacggcagcgccagcagcctggtggaagcggtcttgatttcagaaggactgggacagttt
gctcaagatcccaagttcatcgaggtcaccacacaggagctggctgacgcctgcgatatg
acaatagaggagatggagaacgccgcagacaacatcctcagcgggggcgcccagcagagc
cccaacggcaccctcttaccttttgtgaactgcagggacccagggcaggacagggctgtg
gtcccagaggacgagagctgtgtatatgccctggggcgaggccggagcgaggaagcgctc
ccggacagcaggtcctatgtcagcaacctgtag
DBGET
integrated database retrieval system
