Streptomyces alboniger: CP975_24170
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Entry
CP975_24170 CDS
T06908
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
salw
Streptomyces alboniger
Pathway
salw00020
Citrate cycle (TCA cycle)
salw00630
Glyoxylate and dicarboxylate metabolism
salw00785
Lipoic acid metabolism
salw01100
Metabolic pathways
salw01110
Biosynthesis of secondary metabolites
salw01120
Microbial metabolism in diverse environments
salw01200
Carbon metabolism
salw01210
2-Oxocarboxylic acid metabolism
Module
salw_M00009
Citrate cycle (TCA cycle, Krebs cycle)
salw_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
salw00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
CP975_24170
00630 Glyoxylate and dicarboxylate metabolism
CP975_24170
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CP975_24170
Enzymes [BR:
salw01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
CP975_24170
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
CP975_24170
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
CP975_24170
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
CP975_24170
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
QEV20215
UniProt:
A0A5J6HU14
LinkDB
All DBs
Position
complement(5362236..5366051)
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AA seq
1271 aa
AA seq
DB search
MKRKRAVTAVSSQSPSSSSTSTDQDAQGKDPAAAFGPNEWLVDEIYQQYLQDPNSVDRAW
WDFFADYKPGVGASVAATPAQPAGDAAAGAASTTAPAAPAAKPAPAAPAPATPAAQTAKP
ATAAPAAPAAKPAAAKPAAKAEPAKEAPAGPEYTTLRGPAAAVAKNMNASIEVPTATSVR
AVPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPSMNYSFVEKDGKPTLV
KPEHINFGLAIDLVKPNGDRQLVVAGIKKAETMNFFEFWQAYEDIVRRARDGKLGMDDFT
GVTVSLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGISKVMTLT
STYDHRVIQGAASGEFLRIVANLLLGEQDFYDEIFEALRIPYEPVRWLKDIDASHDDDVT
KAARVFELIHSYRVRGHVMADTDPLEYKQRKHPDLDITEHGLTLWDLEREFAVGGFAGKS
MMKLRDVLGVLRDSYCRTTGVEFMHIQDPKQRKWLQDRIERQHATKPEREEQLRILRRLN
AAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVIGMAHRGRLNVLA
NIVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLAANPSHLEA
VDPVLEGIVRAKQDIINKGGTDFTVLPVALHGDAAFAGQGVVAETLNMSQLRGYRTGGTV
HVVINNQVGFTAAPESSRSSMYSTDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFN
KDVVIDLICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQA
LQDYQGQLEKVFTEVREATSQSAPVEVPGPEAEFPVAVNTAISQEVVKRIAESQVNIPDR
VTVHPRLLPQLQRRAAMVEDGTIDWGMGETLAIGSLLMEGTPVRLAGQDSRRGTFGQRHA
VLIDRETGDDYTPLLYLSEEQARFNAYDSLLSEYAAMGFEYGYSLARPESLVMWEAQFGD
FVNGAQTVVDEFISSAEQKWGQTSGVTLLLPHGYEGQGPDHSSARPERFLQLCAQNNMTV
AMPTLPSNYFHLLRWQVHNPHHKPLVVFTPKWMLRLKAAASKTEEFTSGSFRPVIGDASV
DPKAVRKVVFCAGKLYYELEAERQKRGVTDTAIIRIERLYPLPGAELQEEISKYPNAEKY
LWAQEEPANQGAWPFIALNLIDHLDLAVGADIPHGERLRRISRPHGSSPAVGSKKRHEQE
QAQLLSEVFEA
NT seq
3816 nt
NT seq
+upstream
nt +downstream
nt
gtgaagcggaagagggcggttaccgccgtgtcgtcacagtcccccagtagctcgagcact
tcgaccgaccaagacgcgcagggcaaggaccctgccgccgccttcggtcccaatgagtgg
ctcgtagacgagatctatcagcagtacctccaggacccgaattcggtcgaccgagcctgg
tgggacttcttcgccgactacaagccgggggtgggcgcttccgtagccgccaccccggcg
cagccggcgggtgacgcggccgcgggggccgcgtccaccactgctcccgccgcgccggcc
gcgaagcccgcgcccgccgcaccggctcccgcgacgcccgcggcccagaccgcgaagccc
gccaccgcggcccccgcggcccccgccgccaagcccgccgccgcgaagcccgccgccaag
gcggagcccgcgaaggaggccccggcaggacccgagtacacgacgctgcgcggcccggcc
gccgcggtcgcgaagaacatgaacgcctcgatcgaggtcccgacggccacgtcggtccgc
gcggtcccggtgaagctgctcttcgacaaccgcatcgtcatcaacaaccacctcaagcgc
gcccgcggcgggaagatctccttcacgcacctcatcgggtacgcgatggtgcaggccatc
aaggccatgccgtcgatgaactactccttcgtggagaaggacggcaagccgaccctggtc
aagccggagcacatcaacttcggcctcgccatcgacctggtgaagcccaacggcgaccgc
cagctcgtggtcgcgggcatcaagaaggccgagaccatgaacttcttcgagttctggcag
gcctacgaggacatcgtccgccgcgcccgcgacggcaagctcggcatggacgacttcacc
ggcgtcacggtctccctgaccaaccccggcggcctcggcaccgtccactcggtcccgcgt
ctgatgcccggccagtcggtcatcatgggcgtcggctccatggactaccccgcggagttc
cagggcacctcccaggacaccctgaacaagctcggcatctcgaaggtcatgacgctcacg
tcgacctacgaccaccgggtcatccagggcgccgcctccggcgagttcctgcgcatcgtc
gcgaacctcctcctcggtgagcaggacttctacgacgagatcttcgaggctctgcggatc
ccctacgagccggtccgctggctcaaggacatcgacgcctcgcacgacgacgacgtcacg
aaggccgcccgcgtcttcgagctgatccactcctaccgcgtccgcggccacgtcatggcc
gacacggacccgctggagtacaagcagcgcaagcaccccgacctggacatcaccgagcac
ggcctcaccctgtgggacctggagcgggagttcgcggtcggcggcttcgccggcaagtcg
atgatgaagctgcgcgacgtcctcggcgtgctgcgcgactcgtactgccgcaccaccggc
gtcgagttcatgcacatccaggacccgaagcagcgcaagtggctccaggaccgcatcgag
cgccagcacgccacgaagccggagcgcgaggagcagctgcgcatcctgcgccgcctgaac
gccgcggaggcgttcgagaccttcctccagaccaagtacgtcggccagaagcgcttctcg
ctggagggcggcgagtccgtcatcccgctgctcgacgccgtcatcgactcggcggccgag
tcgcgcctggacgaggtcgtcatcggcatggcccaccgcggccgcctgaacgtgctcgcg
aacatcgtcggcaagtcgtacgcccagatcttccgcgagttcgagggcaacctcgacccg
aagtcgatgcacggctccggcgacgtgaagtaccacctgggcgccgagggcaccttcacg
ggcctggacggcgagcagatcaaggtctccctggccgccaacccctcccacctggaggcg
gtcgacccggtcctggaaggcatcgtccgcgccaagcaggacatcatcaacaagggcggc
acggacttcacggtcctgcccgtcgccctgcacggtgacgcggccttcgcgggccagggc
gtggtcgccgagaccctgaacatgtcgcagctgcgcggctaccgcacgggcggcacggtc
cacgtcgtcatcaacaaccaggtcggcttcaccgccgccccggagtcgtcccgctcgtcg
atgtactcgacggacgtggcgcggatgatcgaggcgccgatcttccacgtgaacggcgac
gacccggaggccgtggtccgcgtggcccgcctggccttcgagttccgtcaggcgttcaac
aaggacgtcgtgatcgacctcatctgctaccgccgccgcggtcacaacgagtcggacaac
ccggcgttcacccagccgctgatgtacgacctgatcgacaagaagcgctcggtgcgcaag
ctctacaccgagtccctcatcggtcgcggcgacatcaccctggaagaggccgagcaggcg
ctccaggactaccagggccagctggagaaggtcttcaccgaggtccgcgaggccacctcg
cagtccgcgccggtggaggtccccggccccgaggccgagttcccggtcgcggtgaacacg
gcgatctcccaggaggtcgtcaagcgcatcgccgagtcccaggtcaacatccccgaccgc
gtcaccgtgcacccgcgcctgctgccgcagctccagcgccgcgcggccatggtcgaggac
ggcacgatcgactggggcatgggcgagaccctcgccatcggctcgctgctcatggagggc
accccggtgcgcctcgcgggccaggactcgcgccgcggcacgttcggccagcgccacgcg
gtcctcatcgaccgcgagacgggcgacgactacacgccgctgctgtacctctccgaggag
caggcccgcttcaacgcctacgactcgctcctgtccgagtacgcggcgatgggcttcgag
tacggctactccctggcccgtcccgagtccctcgtgatgtgggaggcccagttcggtgac
ttcgtcaacggcgcgcagaccgtcgtcgacgagttcatctcctcggccgagcagaagtgg
ggccagacgtccggcgtcaccctgctcctcccgcacggctacgagggccagggcccggac
cactcgtccgcccgcccggagcgcttcctccagctgtgcgcgcagaacaacatgacggtc
gcgatgccgaccctcccgtcgaactacttccacctcctgcggtggcaggtgcacaacccg
caccacaagccgctggtggtcttcaccccgaagtggatgctgcgcctgaaggccgccgcg
tccaagacggaggagttcacctcgggcagcttccgcccggtcatcggcgacgcgtccgtg
gacccgaaggcggtccgcaaggtcgtcttctgcgcgggcaagctctactacgagctggag
gccgagcggcagaagcgcggtgtcacggacacggcgatcatccgcatcgagcgtctgtac
ccgctgccgggcgcggagctccaggaggagatctccaagtatccgaacgccgagaagtac
ctgtgggcgcaggaggagccggcgaaccagggcgcgtggcccttcatcgccctcaacctc
atcgaccacctggacctggcggtcggcgccgacatcccgcacggcgagcgtctgcgccgc
atctcgcggccgcacggctcgtcccccgcggtcggctcgaagaagcgccacgagcaggag
caggcgcagctcctgagcgaggtcttcgaggcctag
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