Sarcophilus harrisii (Tasmanian devil): 100921875 Help Entry 100921875         CDS       T02286                                  Symbol TNF Name (RefSeq) tumor necrosis factor   KO K03156   tumor necrosis factor superfamily, member 2 Organism shr  Sarcophilus harrisii (Tasmanian devil) Pathway shr01523   Antifolate resistance shr04010   MAPK signaling pathway shr04060   Cytokine-cytokine receptor interaction shr04061   Viral protein interaction with cytokine and cytokine receptor shr04064   NF-kappa B signaling pathway shr04071   Sphingolipid signaling pathway shr04150   mTOR signaling pathway shr04210   Apoptosis shr04217   Necroptosis shr04350   TGF-beta signaling pathway shr04380   Osteoclast differentiation shr04612   Antigen processing and presentation shr04620   Toll-like receptor signaling pathway shr04621   NOD-like receptor signaling pathway shr04622   RIG-I-like receptor signaling pathway shr04625   C-type lectin receptor signaling pathway shr04640   Hematopoietic cell lineage shr04650   Natural killer cell mediated cytotoxicity shr04657   IL-17 signaling pathway shr04660   T cell receptor signaling pathway shr04664   Fc epsilon RI signaling pathway shr04668   TNF signaling pathway shr04920   Adipocytokine signaling pathway shr04930   Type II diabetes mellitus shr04931   Insulin resistance shr04932   Non-alcoholic fatty liver disease shr04933   AGE-RAGE signaling pathway in diabetic complications shr04936   Alcoholic liver disease shr04940   Type I diabetes mellitus shr05010   Alzheimer disease shr05014   Amyotrophic lateral sclerosis shr05020   Prion disease shr05022   Pathways of neurodegeneration - multiple diseases shr05132   Salmonella infection shr05133   Pertussis shr05134   Legionellosis shr05135   Yersinia infection shr05140   Leishmaniasis shr05142   Chagas disease shr05143   African trypanosomiasis shr05144   Malaria shr05145   Toxoplasmosis shr05146   Amoebiasis shr05152   Tuberculosis shr05160   Hepatitis C shr05161   Hepatitis B shr05163   Human cytomegalovirus infection shr05164   Influenza A shr05165   Human papillomavirus infection shr05166   Human T-cell leukemia virus 1 infection shr05168   Herpes simplex virus 1 infection shr05169   Epstein-Barr virus infection shr05170   Human immunodeficiency virus 1 infection shr05171   Coronavirus disease - COVID-19 shr05205   Proteoglycans in cancer shr05310   Asthma shr05321   Inflammatory bowel disease shr05322   Systemic lupus erythematosus shr05323   Rheumatoid arthritis shr05330   Allograft rejection shr05332   Graft-versus-host disease shr05410   Hypertrophic cardiomyopathy shr05414   Dilated cardiomyopathy shr05417   Lipid and atherosclerosis shr05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:shr00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100921875 (TNF)    04350 TGF-beta signaling pathway     100921875 (TNF)    04064 NF-kappa B signaling pathway     100921875 (TNF)    04668 TNF signaling pathway     100921875 (TNF)    04071 Sphingolipid signaling pathway     100921875 (TNF)    04150 mTOR signaling pathway     100921875 (TNF)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     100921875 (TNF)    04061 Viral protein interaction with cytokine and cytokine receptor     100921875 (TNF)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     100921875 (TNF)    04217 Necroptosis     100921875 (TNF)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     100921875 (TNF)    04620 Toll-like receptor signaling pathway     100921875 (TNF)    04621 NOD-like receptor signaling pathway     100921875 (TNF)    04622 RIG-I-like receptor signaling pathway     100921875 (TNF)    04625 C-type lectin receptor signaling pathway     100921875 (TNF)    04650 Natural killer cell mediated cytotoxicity     100921875 (TNF)    04612 Antigen processing and presentation     100921875 (TNF)    04660 T cell receptor signaling pathway     100921875 (TNF)    04657 IL-17 signaling pathway     100921875 (TNF)    04664 Fc epsilon RI signaling pathway     100921875 (TNF)   09152 Endocrine system    04920 Adipocytokine signaling pathway     100921875 (TNF)   09158 Development and regeneration    04380 Osteoclast differentiation     100921875 (TNF)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     100921875 (TNF)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100921875 (TNF)    05170 Human immunodeficiency virus 1 infection     100921875 (TNF)    05161 Hepatitis B     100921875 (TNF)    05160 Hepatitis C     100921875 (TNF)    05171 Coronavirus disease - COVID-19     100921875 (TNF)    05164 Influenza A     100921875 (TNF)    05168 Herpes simplex virus 1 infection     100921875 (TNF)    05163 Human cytomegalovirus infection     100921875 (TNF)    05169 Epstein-Barr virus infection     100921875 (TNF)    05165 Human papillomavirus infection     100921875 (TNF)   09171 Infectious disease: bacterial    05132 Salmonella infection     100921875 (TNF)    05135 Yersinia infection     100921875 (TNF)    05133 Pertussis     100921875 (TNF)    05134 Legionellosis     100921875 (TNF)    05152 Tuberculosis     100921875 (TNF)   09174 Infectious disease: parasitic    05146 Amoebiasis     100921875 (TNF)    05144 Malaria     100921875 (TNF)    05145 Toxoplasmosis     100921875 (TNF)    05140 Leishmaniasis     100921875 (TNF)    05142 Chagas disease     100921875 (TNF)    05143 African trypanosomiasis     100921875 (TNF)   09163 Immune disease    05310 Asthma     100921875 (TNF)    05322 Systemic lupus erythematosus     100921875 (TNF)    05323 Rheumatoid arthritis     100921875 (TNF)    05321 Inflammatory bowel disease     100921875 (TNF)    05330 Allograft rejection     100921875 (TNF)    05332 Graft-versus-host disease     100921875 (TNF)   09164 Neurodegenerative disease    05010 Alzheimer disease     100921875 (TNF)    05014 Amyotrophic lateral sclerosis     100921875 (TNF)    05020 Prion disease     100921875 (TNF)    05022 Pathways of neurodegeneration - multiple diseases     100921875 (TNF)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     100921875 (TNF)    05418 Fluid shear stress and atherosclerosis     100921875 (TNF)    05410 Hypertrophic cardiomyopathy     100921875 (TNF)    05414 Dilated cardiomyopathy     100921875 (TNF)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     100921875 (TNF)    04940 Type I diabetes mellitus     100921875 (TNF)    04936 Alcoholic liver disease     100921875 (TNF)    04932 Non-alcoholic fatty liver disease     100921875 (TNF)    04931 Insulin resistance     100921875 (TNF)    04933 AGE-RAGE signaling pathway in diabetic complications     100921875 (TNF)   09176 Drug resistance: antineoplastic    01523 Antifolate resistance     100921875 (TNF)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and neuropeptides [BR:shr04052]     100921875 (TNF)    00536 Glycosaminoglycan binding proteins [BR:shr00536]     100921875 (TNF) Cytokines and neuropeptides [BR:shr04052]  Cytokines   Tumor necrosis fators    100921875 (TNF) Glycosaminoglycan binding proteins [BR:shr00536]  Heparan sulfate / Heparin   Cytokines    100921875 (TNF) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  TNF Form-deh_trans Motif Other DBs NCBI-GeneID:  100921875 NCBI-ProteinID:  XP_023358642 LinkDB All DBs Position 4:complement(285452198..285454862) Genome browser AA seq 232 aa AA seqDB search MSTESMIRDVELAEEALQRKARGPQGPGRCLCLTLVSFLFLAGATILFCLLHFGVIGPQK EEEQDAFRSMKPLTQRVRSCLSESDKPVAHVVANPKAEGQLQWLNRSANTLLNNGMELKD NQLVVPATGLYLVYSQLLFKGEDCASEPLFLTHTISRVSLSYQHKVSLLAAIKSPCQKAT QGAREANPWYEPIYLGGVFQLDKGDKLSSDTNYPKYLDLAESGQVYFGIIAL NT seq 699 nt NT seq  +upstreamnt  +downstreamnt atgagcacagagagtatgatccgagacgtggaactagcagaagaggcactccaaaggaag gcaagggggccccaaggccctggacgctgcctctgcctcacacttgtctccttccttttt cttgctggggctactattctcttctgcctgctgcacttcggtgtgataggacctcagaag gaagaggagcaggatgcctttcgtagcatgaaacctttgactcagagagtcagatcttgt ctcagtgaaagtgacaagcctgtagctcatgttgtagctaatcccaaggcagaggggcag ctccagtggttgaataggagtgccaatactctcctgaataatggcatggaactgaaagac aaccagctggtggtgcctgccaccgggctctacctggtctactcccagctccttttcaag ggagaggattgtgccagtgaacccctgttcctcactcataccatctcccgggtttcattg tcctaccaacacaaagtcagccttcttgctgccatcaagagtccgtgccagaaggcaaca caaggagctagggaggctaatccctggtatgaaccaatctatctggggggtgtcttccag cttgacaaaggtgataagctcagttctgacaccaactatccaaaatatcttgacttagct gagtctggccaggtctattttgggatcattgctctttga

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