KEGG   Sphingomonas sp. MM-1: G432_13410
Entry
G432_13410        CDS       T02498                                 
Name
(GenBank) hydrophobe/amphiphile efflux-1 (HAE1) family protein
  KO
K18138  multidrug efflux pump
Organism
sphm  Sphingomonas sp. MM-1
Pathway
sphm01501  beta-Lactam resistance
sphm01503  Cationic antimicrobial peptide (CAMP) resistance
Brite
KEGG Orthology (KO) [BR:sphm00001]
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    G432_13410
   01503 Cationic antimicrobial peptide (CAMP) resistance
    G432_13410
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:sphm02000]
    G432_13410
   01504 Antimicrobial resistance genes [BR:sphm01504]
    G432_13410
Transporters [BR:sphm02000]
 Other transporters
  Electrochemical potential-driven transporters [TC:2]
   G432_13410
Antimicrobial resistance genes [BR:sphm01504]
 Gene sets
  Multipdrug resistance modules
   Multidrug resistance, efflux pump MexAB-OprM [MD:M00718]
    G432_13410
SSDB
Motif
Pfam: ACR_tran SecD_SecF SHOCT
Other DBs
NCBI-ProteinID: AGH50400
UniProt: M4S2Z2
LinkDB
Position
complement(2836466..2839648)
AA seq 1060 aa
MLSRIFIDRPIFAWVIAIVIMLLGIGGILTLPVEQYPDIAPPSVNIRATYPGASAETIES
SVTQVIEQQLTGIDGLIYFQSTSNSSGSVTVTVTFQKGTDPDIAQVQVQNKVQQALPRLP
QQVQQQGLVVTKSNADFLMVVSIYDETDRMTSADVSDYLVSNLQDPIGRLAGVGDVNVFG
SQYAMRIWLDPFKLSAVQLMPADVIAAIQAQNTQVAAGQIGGQPSPDSQMLNAIVTARSR
LTTADQFRDIIVKTQTDGSKVLLRDVARVELGSESYNNVSRLNGHPGAGIAIQLAPGADA
LKTAKLVRSYVDGHASAFPQGLRYAYPNDSTAFIKLSVEDVIKTLIEAIILVVLVMFVFL
QSWRATLIPAIAVPVVLLGTFGVLAAFGFSINTLTLFGMVLAIGLLVDDAIVVVENVERV
MEEEPDISPRDATIKSMSEINIALIAIALVLSAVFLPMAFFGGSTGVIYKQFSITIVSSM
VLSVVVALILSPALAATLLKRPDHAARRGGPWIVQRAHHYGDRFNAWFARMSEGYRARVA
RLFGHMKAALLVYGAIVVLLVLVFLKLPTSFLPVEDQGIAQLQFTLPAGATQARTIAAAK
TIERYFLGTEGKNTNVVYAVIGGNQAGTGQNAGRGFLSLAPWDERKGSANSAEAITRRAT
AELGREMRDVQFYALNPPAVRGLGQSSGFTLELLNSGGLSREEFKARRDQLIAEASADPI
LAQVRQNSLEDTPTLSVQIDQAKVGALGLTQAAVDQTLSAAWGGNYVNDFVDRGRVKRVY
VQGDAPYRSRPEDLANWFVRGASGQMAPFSAFAHIDWGRAPNTLTRFNGLASYEIQGQSA
PGKSSGDAMARIAELAGQLPGVSIAWAGLSYQEQISGGQAPYLYGLSLLVVFLCLAALYE
SWSIPFAVMLVMPLGLIGATLAVLARGLENDIYFQVGLLTTMGLSAKNAILIVEFAEQAE
RQGRTAVEAALEAARIRLRPILMTSLAFIFGVLPLAISTGAGAKSRVAIGTAVMGGMITA
TVLAIFFVPLFFVLVRRLFRKGHAEKPDGPASGGAAEALA
NT seq 3183 nt   +upstreamnt  +downstreamnt
gtgctgtcacgcatcttcatcgatcggcccatcttcgcatgggtcatcgccatcgtcatc
atgctgctgggcatcggcggcatattgacgctgccggtggagcaatatcccgatatcgcg
ccgccctcggtcaacatccgcgccacctatccgggcgcgtcggccgaaacgatcgaatcc
agcgtcacccaggtgatcgagcagcagctcaccggcatcgacgggctgatctacttccag
tccacctcgaactcgtccggctcggtcacggtcaccgtcaccttccagaagggcacggac
ccggacatcgcccaggtccaggtgcagaacaaggtgcagcaggcgctgccccgcctgccc
cagcaggtccagcagcagggcctggtcgtcacgaaatccaacgcggatttcctgatggtg
gtgtcgatctacgacgagacggatcggatgacgagcgccgacgtcagcgactatctcgtc
tccaacctgcaggatccgatcggccgcctcgcgggcgtcggcgacgtcaatgtgttcgga
tcgcaatatgcgatgcggatctggctcgatcccttcaagctttccgcggtccagctcatg
ccggcggacgtgatcgcggcgatccaggcgcagaacacgcaggtcgccgccggccagatc
ggcggccagccctcgcccgacagccagatgctgaacgcgatcgtcacggcgcggtcccgc
ctcaccacggcggatcagttccgcgacatcatcgtcaagacgcagacggacggctccaag
gtgctgctgcgcgatgtcgcgcgggtggagctgggcagcgaaagctacaacaatgtcagc
cggctcaacggccatcccggcgccggcatcgccatccagctcgcgccgggggcggacgcg
ctcaagacggcgaagctggtgcgcagctatgtcgacggccacgcctccgctttcccgcag
gggctgcgctacgcctatcccaacgacagcaccgccttcatcaagctttcggtggaagac
gtcatcaagacgctgatcgaggcgatcatcctcgtcgtcctggtgatgttcgtcttcctc
cagagctggcgggcgacgctgatcccggccatcgccgtgccggtggtgctgctcggcacc
ttcggcgtgctcgcggccttcggcttctcgatcaacacgctcaccttgttcggcatggtg
ctggcgatcggcctgctcgtcgacgacgcgatcgtcgtggtcgagaatgtcgagcgcgtg
atggaggaggagccggacatctccccccgcgacgccacgatcaagtcgatgtcggaaatc
aacatcgcgctgatcgcgatcgcgctggtgctgtcggcggtgttcctgccgatggccttc
ttcggcgggtccaccggcgtcatctacaagcagttctcgatcaccatcgtctcctcgatg
gtgctttcggtggtggtggccctcatcctctcgcccgcgctggcggccaccctgctcaag
cggccggatcacgcggcccggcgcggcggcccctggatcgtccagcgcgcgcaccattat
ggcgatcgcttcaacgcctggttcgcgcgcatgtccgaaggctatcgcgcccgcgtcgcc
cgcctgttcggccacatgaaggcggcgctcctcgtctatggcgccatcgtcgtgctgctc
gtcctcgtcttcctgaagctgccgaccagcttcctgcccgtggaggaccagggcatcgcc
cagctccagttcaccctgccggcgggcgccacccaggcccgcaccatcgcggcggccaag
acgatcgagcgctatttcctggggacggagggcaagaacaccaacgtcgtctatgcggtc
atcggcggcaaccaggcgggcaccggccagaatgccgggcgcggcttcctgtcgctggcg
ccgtgggacgagcgcaagggttcggccaacagcgcggaggcgatcacccgccgcgcgacg
gcggagctgggccgcgagatgcgcgacgtccagttctacgcgctcaacccgcccgccgtg
cgcggcctcggccagtcgagcggcttcacgctggagctgctcaactccggcggcctcagc
cgggaggagttcaaggcccgccgcgatcagctcatcgcggaggcgtccgccgatcccatc
ctcgcccaggtccgccagaacagcctggaggatacgcccaccttgtcggtccagatcgat
caggcgaaggtcggcgcgctcggcctcacccaggcggcggtcgatcagacgctgtcggcc
gcgtggggcggcaactatgtcaacgatttcgtcgatcgcggccgggtgaagcgcgtctat
gtccagggcgacgccccctatcgcagccggccggaggatctcgccaactggttcgtgcgc
ggcgcgtccgggcagatggcgcccttctcggccttcgcccatatcgattggggccgcgcg
cccaacacgctcacccgcttcaacggcctcgcttcctacgagattcagggccagtcggcg
ccgggcaagagctcgggcgacgcgatggcgcgcatcgccgagcttgcgggccagcttccc
ggcgtctccatcgcctgggcgggcctgtcctatcaggaacagatttcgggcgggcaggcg
ccctatctctacggcctgtcgctgctcgtcgtgttcctctgcctcgcggcgctttacgaa
agctggtccatccccttcgcggtgatgctggtgatgccgctcggcctgatcggcgcgacc
ctggcggtgctggcgcgcgggctggaaaacgacatctatttccaggtcggcctgctcacc
accatggggctttcggccaagaacgccatcctgatcgtggaattcgccgagcaggcggaa
cggcagggccgcacggcggtggaagccgcgctggaggccgcccgcatccgcctgcgcccg
atcctgatgaccagcctcgccttcatcttcggcgtgctgccgctcgccatctccaccggc
gccggcgccaagagccgggtggcgatcggcacggcggtgatgggcgggatgatcaccgcc
acggtgctggcgatcttcttcgtgccgctcttcttcgtcctcgtccgcaggctgttccgc
aagggccatgcggaaaagccggacggcccggcatccggcggcgccgcggaggcgctggca
tga

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