Streptomyces tsukubensis: B7R87_23205
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Entry
B7R87_23205 CDS
T07155
Name
(GenBank) 2-oxoglutarate dehydrogenase E1 component
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
stsu
Streptomyces tsukubensis
Pathway
stsu00020
Citrate cycle (TCA cycle)
stsu00630
Glyoxylate and dicarboxylate metabolism
stsu00785
Lipoic acid metabolism
stsu01100
Metabolic pathways
stsu01110
Biosynthesis of secondary metabolites
stsu01120
Microbial metabolism in diverse environments
stsu01200
Carbon metabolism
stsu01210
2-Oxocarboxylic acid metabolism
Module
stsu_M00009
Citrate cycle (TCA cycle, Krebs cycle)
stsu_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
stsu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
B7R87_23205
00630 Glyoxylate and dicarboxylate metabolism
B7R87_23205
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
B7R87_23205
Enzymes [BR:
stsu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
B7R87_23205
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
B7R87_23205
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
B7R87_23205
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
B7R87_23205
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
Transket_pyr
2-oxoacid_dh
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
AZK96455
UniProt:
A0A5H2U7I7
LinkDB
All DBs
Position
complement(5521341..5525222)
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AA seq
1293 aa
AA seq
DB search
MSSQSPSNANSPSLRPGGAPTADRGTPGQGPAAAFGANEWLVDEIYQQYLQDRDSVDRAW
WDFFADYKPGGKNTAEAPAEGAAAAPAAAASTAPAPATVPAPAPQQPAPVSAPAPAAQPA
PAAAPAAPAAPAAPAAKAPVAPAAPAAPAVKPPAAPAAKPAAAKAPEAAAPAGPELITLR
GPSAAVAKNMNASLEVPTATSVRAVPVKLLFDNRIVINNHLKRARGGKVSFTHLIGFAMV
QALRAMPSMNWSFAEKDGKPTLVKPEHVNFGLAIDLVKPNGDRQLVVAAIKKAETLNFFE
FWQAYEDIVRRARSNKLTMDDFTGVTVSLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYP
AEFQGTSQDTLNKLGISKVMTLTSTYDHRVIQGAASGEFLRVVANFLLGEEGFYDQIFEA
LRIPYEPVRWLKDIDASHDDDVTKAARVFELIHSYRVRGHVMADTDPLEYRQRKHPDLDI
TEHGLTLWDLEREFAVGGFAGKSLMKLRDVLGVLRDSYCRTTGIEFMHIQDPKQRKWIQD
RVERPHSKPEREEQLRILRRLNAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSA
AEARLDEVVIGMAHRGRLNVLANIVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGT
FTGLDGEQIKVSLVANPSHLEAVDPVLEGVARAKQDVINKGGTDFTVLPVALHGDAAFAG
QGVVAETLNMSQLRGYRTGGTVHVVINNQVGFTAAPESSRSSMYATDVARMIEAPIFHVN
GDDPEACVRVARLAFEFRQTFNKDVVIDLICYRRRGHNEGDNPQFTNPQMVALIDKKRSV
RKLYTESLIGRGDITLEEAEQALQDFQGQLEKVFAEVREATSHPAPTLVPDPQAEFPVAV
TTAVSQEVIKRIAESQVNIPDNITVHPRLLPQLQRRAASVEDGTIDWGMGETLAIGSLLM
EGTPVRLSGQDTRRGTFGQRHAVLVDQETNEDYTPLLYLTDEQARYNVYDSLLSEYAAMG
FEYGYSLARPESLVMWEAQFGDFVNGAQTVVDEFISSAEQKWGQTSGVTLLLPHGYEGQG
PDHSSARPERFLQMCAQNNMTVAMPTLPSNYFHLLRWQVHNPHHKPLIVFTPKSMLRLKA
AQSKTEEFLNGGFRPVIGDESVDPNAVRKVVFTSGKVYYDLDAERKKRGITDTAILRLER
LYPLPGAELQAEIAKFPNAEKYIWAQEEPANQGAWPFIALNLIDHLDLAVGADVPHGERL
RRISRPHGSSPAVGSAKRHQAEQTQLVADVFDA
NT seq
3882 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgtctcagtcccccagtaacgccaattcccccagccttcggccgggtggggccccc
acggccgaccgaggcacgccgggccagggccctgccgccgccttcggtgccaatgagtgg
ctcgtcgacgagatctaccagcagtacctccaggatcgcgattcggtagaccgcgcctgg
tgggacttcttcgccgactacaagcccggcgggaagaacaccgccgaggctccggccgag
ggtgctgccgcagccccggccgccgcggcatccaccgccccggctccggcgaccgtcccc
gctccggctccgcagcagccggccccggtgtccgctccggcaccggccgcgcagcccgct
ccggccgcggcgcccgccgccccggcagcccccgccgcacccgcggcgaaggcgcccgtg
gctccggctgcacccgcggcacccgcggtcaagccgcccgctgctccggcggcgaagccc
gccgcggccaaggcccccgaggccgcggctccggccgggcccgagctgatcaccctgcgc
ggcccctccgccgccgtcgcgaagaacatgaacgcctccctggaggtgcccacggccacg
tccgtgcgcgccgtcccggtgaagctgctcttcgacaaccgcatcgtcatcaacaaccac
ctgaagcgcgcccggggcgggaaggtctccttcacccacctcatcggcttcgccatggtg
caggccctgcgggccatgccgtcgatgaactggtcgttcgcggagaaggacggcaagccg
accctggtcaagccggagcacgtcaacttcggcctcgccatcgacctggtgaagccgaac
ggcgaccgccagctcgtcgtcgcggccatcaagaaggccgagaccctcaacttcttcgag
ttctggcaggcgtacgaggacatcgtccgccgcgcccgcagcaacaagctgacgatggac
gacttcaccggcgtcaccgtctcgctgaccaaccccggcggcctcggcacggtccactcc
gtgccccggctgatgcccggccagtcggtgatcatgggcgtcggctccatggactacccc
gccgagttccagggcacctcccaggacaccctgaacaagctgggcatctccaaggtcatg
acgctgacctcgacctacgaccaccgggtcatccagggtgcggcgtccggcgagttcctg
cgcgtcgtggccaacttcctcctcggcgaggagggcttctacgaccagatcttcgaggcc
ctgcggatcccctacgagccggtccgctggctcaaggacatcgacgcgtcccacgacgac
gacgtcaccaaggccgcccgggtcttcgagctgatccactcctaccgggtccgtggccat
gtcatggccgacaccgacccgctggagtaccgccagcgcaagcaccccgacctcgacatc
accgagcacgggctgaccctgtgggacctggagcgcgaattcgccgtcggcggtttcgcg
ggcaagtccctgatgaagctccgcgacgtcctcggcgtgctccgcgactcgtactgccgc
accaccggcatcgagttcatgcacatccaggaccccaagcagcgcaagtggatccaggac
cgggtcgagcgcccgcactccaagccggagcgcgaggagcagctgcggatcctgcgccgg
ctgaacgccgccgaggccttcgagaccttcctgcagacgaagtacgtcggccagaagcgg
ttctcgctggagggcggcgagtccgtcatcccgctgctcgacgcggtcatcgactccgcc
gccgaggcccgcctcgacgaggtcgtcatcggcatggcccaccgcggccggctcaacgtc
ctcgccaacatcgtgggcaagtcgtacgcccagatcttccgcgagttcgagggcaacctc
gacccgaagtcgatgcacggctccggcgacgtcaagtaccacctgggcgccgagggcacc
ttcaccggtctcgacggcgagcagatcaaggtctccctggtcgccaacccctcccatctg
gaggccgtcgacccggtcctcgaaggcgtcgcccgcgccaagcaggacgtgatcaacaag
ggcggcaccgacttcaccgtgctgcccgtcgccctccacggcgacgcggccttcgcgggc
cagggcgtcgtcgccgagacgctgaacatgtcgcagctccgcggctaccgcaccggcggc
acggtccacgtcgtcatcaacaaccaggtcggcttcaccgccgcaccggagtcctcgcgc
tcctcgatgtacgcgacggacgtcgcccggatgatcgaagcgccgatcttccacgtcaac
ggcgacgaccccgaggcctgtgtccgggtcgcccggctggccttcgagttccgccagacg
ttcaacaaggacgtcgtgatcgacctcatctgctaccgccgccgcggtcacaacgagggc
gacaacccgcagttcaccaacccgcagatggtcgcgctgatcgacaagaagcgttcggtg
cgcaagctgtacaccgagtccctgatcggccgcggcgacatcaccctcgaagaggcggag
caggcgctccaggacttccagggccagctggagaaggtgttcgcggaggtccgcgaggcc
accagccacccggcgccgaccctggtgccggacccgcaggccgaattcccggtcgccgtg
accaccgcggtgtcccaggaggtcatcaagcggatcgccgagtcccaggtcaacatcccg
gacaacatcaccgtccacccgcggctgctgccgcagctccagcgccgggccgcctccgtc
gaggacggcacgatcgactggggcatgggcgagacgctcgccatcggctccctgctgatg
gagggcaccccggtccggctctccggccaggacacccggcgcggcaccttcggccagcgc
cacgcggtcctggtcgaccaggagaccaacgaggactacaccccgctgctctacctgacc
gacgagcaggcccgctacaacgtctacgactccctgctcagcgagtacgcggcgatgggc
ttcgagtacggctactcgctggcccgccccgaatcgctggtcatgtgggaggcgcagttc
ggtgacttcgtcaacggcgcacagaccgtcgtcgacgagttcatctcctccgccgagcag
aagtggggccagacctccggcgtcaccctgctgctgccgcacggctacgagggccagggc
ccggaccactcgtccgcccgccccgagcgcttcctccagatgtgcgcgcagaacaatatg
acggtcgccatgccgacgctgccgtcgaactacttccatctgctgcggtggcaggtgcac
aacccgcaccacaagccgctgatcgtcttcaccccgaagtcgatgctccggctcaaggcc
gcgcagtcgaagacggaggagttcctcaacggcggcttccgcccggtcatcggtgacgag
tcggtcgacccgaacgcggtccgcaaggtggtcttcacctccggcaaggtctactacgac
ctcgacgcggagcggaagaagcgcggcatcacggacaccgcgatcctccgtcttgagcgg
ctgtacccgctgccgggtgcggagctgcaggccgagatcgccaagttcccgaacgccgag
aagtacatctgggcgcaggaggagccggcgaaccagggtgcgtggccgttcatcgcgctg
aacctgatcgaccacctggacctggcggtcggcgcggacgtgccgcacggcgagcgcctg
cgccgcatctcgcggccgcacggctcgtcgcccgcggtgggctcggcgaagcggcaccag
gcggagcagacgcagctggtggcggacgtcttcgacgcgtag
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