Trueperella pyogenes TP6375: CQ11_10200
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Entry
CQ11_10200 CDS
T03070
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
tpy
Trueperella pyogenes TP6375
Pathway
tpy00020
Citrate cycle (TCA cycle)
tpy00630
Glyoxylate and dicarboxylate metabolism
tpy00785
Lipoic acid metabolism
tpy01100
Metabolic pathways
tpy01110
Biosynthesis of secondary metabolites
tpy01120
Microbial metabolism in diverse environments
tpy01200
Carbon metabolism
tpy01210
2-Oxocarboxylic acid metabolism
Module
tpy_M00009
Citrate cycle (TCA cycle, Krebs cycle)
tpy_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
tpy00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
CQ11_10200 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
CQ11_10200 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CQ11_10200 (kgd)
Enzymes [BR:
tpy01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
CQ11_10200 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
CQ11_10200 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
CQ11_10200 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
CQ11_10200 (kgd)
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
FliE
Glyco_hydro_38N
Motif
Other DBs
NCBI-ProteinID:
AHU90260
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All DBs
Position
complement(2208010..2211765)
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AA seq
1251 aa
AA seq
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MQRKARQTVSSTNDDFGANQGFIEELYAAYLGNKDGVGPQWAEMFRAWEAEGRTPLLGED
AEHTGETAEKKEVTATQRAVHSQADRASTPSTNVTRSDLPPQPRAAAAPAITPYAKSYTL
RPADAEQDMDPKAKDVTPLKGGDRGLAKNMDASLSIPTATSLRALPARVMFDNRAVINRY
LAATRGGKISFTHLIAYAMVESLAEMPEMNVAYALENGRPALVAPKHVNLGIAIDVVKPD
GARTLVVPSIKAAETMTFSEFVSAYEELVERGRQNKLSIEDYQGTTATLTNPGGLGTTES
VPRLMVGQGLIVGVGSMTYPPEFQGTAEETIARLGISKVVNIGSTYDHRVIQGATSGRFL
RLMETKLLGLDGFYERVYVSLRVPYTPITWEKDVEYDAERELGKPARIAELIHAYRSRGH
LIADTDPLSFHLRRHPDLEISSYGLSLWDLDRSFPTGGFAGTSHLTLRDILTNLRDAYCR
TVGIEYMHIQDPVQRAWFQERLECKPKSTTAQQRIRILEKLNQAEAFEVFLQTKYVGQKR
FSLEGGESLIPALDAILGGAANDGLHQVAIGMAHRGRLNVLTNIAGKSFGQVFSEFDGVM
DPKKPGSGDVKYHLGTEGTYTAANGDQVGVYLAANPSHLEAADGVLEGVARAMQDQLDLD
DDGAAVVPLLIHGDAAFSGQGVVTEVLNLSQLPAYRTGGTVHIIVNNQIGFTTAPSNSRS
SRYTTDIAKGLQLPIFHVNGDDPEAVCRMARMAYDYRMEFRKDVILDIICYRKRGHNEGD
DPSMTQPIMYSLVDEKRSTRQLYREALLGRGDISDEEAAKVEQDFHTLLEQAFQKVRELE
NKAETAQGKAADSLGVPSSQQEDAGTMVGWATAVAPEVLQRIGKAHTTPPEGFTIHKKVM
SLFHKRNAMTHEGHIDWGFGELLAFGSLLIEGVPVRMSGQDSRRGTFTQRHAVVHDSRTG
AEWTPLMGLTEDQARFKIYDSALSEYSIMAFEYGYSVQRPDALVLWEAQFGDFANGAQTV
VDEFISSAEQKWHQSSSIVLLLPHGYEGQGPDHSSARIERYLQLCAEENMVVVQPTTPAN
YFHMLREQAYRRPRKPMIVFSPKQLLRRKGVESTLAEFTSGTVRKVIGETRQLGAVDRVL
LCTGRIYYDLLEQREKDDDERTAIIRVEQLYPNPVDEVRAELEKYPGAEVFWVQDEPANQ
GAWAHFALDMFPQLDRGIARISRPAAASTAAGMASLHRTETAELMRQAFER
NT seq
3756 nt
NT seq
+upstream
nt +downstream
nt
atccaacgaaaagcgaggcagacagtgtcgtcaaccaacgatgattttggagcgaaccag
ggcttcattgaggagctctacgcggcctacctaggcaacaaggatggagtgggtccacag
tgggcggagatgttccgcgcctgggaagcagaagggcgcacgccgctcctcggcgaagat
gccgaacacaccggggagacggcagagaagaaggaagtgacagccacacagcgcgctgtg
cattcccaggccgaccgcgcttccacaccctcgacgaatgtcacgcgctccgacctaccc
ccacagccgcgtgcagccgccgcgcccgccatcacaccctacgccaagtcctacacgctg
cgcccggcagacgccgagcaggacatggatcccaaggccaaagacgtcacgcccctcaag
ggcggcgaccgtgggctagcaaaaaacatggacgcctcgctgtccatccccaccgccacc
tcgctgcgcgcccttcccgcacgcgtcatgttcgacaaccgggccgtcatcaaccgctac
ctggcggccacgcgcggcggaaagatctccttcacccacctcatcgcctacgccatggtc
gaatcgctcgccgaaatgccggagatgaacgtcgcctacgcgctggaaaacggcagaccc
gccctcgttgcgcccaagcatgtcaacctcggcatcgcgatcgacgtcgtcaagcccgac
ggcgcccgcacgctcgtcgtgccctcgatcaaggcagccgaaacgatgacgttctccgag
ttcgtctctgcctacgaagagctcgtcgagcgcgggcgccaaaacaagctcagtatcgag
gactaccaaggcactaccgccacactcaccaatccagggggcctcggtacgaccgagtcc
gtgccacgcctgatggtgggccagggactcattgtcggcgtcggttcgatgacctacccg
cccgagttccagggcaccgccgaggagacgatcgcccgcctgggcatatcgaaagtcgtc
aacatcggctccacctacgatcaccgcgtcattcaaggggcgacctccgggcgcttcctg
cgcctcatggagaccaagctcctcgggctcgatggcttctatgagcgcgtctatgtctca
ctgcgcgtcccctacacgcccatcacgtgggaaaaggacgtcgaatacgacgccgaacgc
gagctcggcaagcccgcgcgcatcgccgagctcatccacgcttatcgctcccgcgggcac
ctcatcgcggacaccgacccgctttctttccacctacgccgccaccccgacctcgagatc
agctcctacggcctgagcctgtgggatctagatcggtccttccccaccggtggcttcgcc
ggcaccagccacctgaccctgcgcgacatcctcaccaaccttcgcgatgcctactgccgc
acggtaggcatcgaatacatgcatatccaagatcctgtgcagcgcgcatggttccaggaa
cgtcttgaatgcaaaccgaaatccacgacggcgcaacagcgcatccgtatcctcgaaaag
ctcaaccaggccgaagccttcgaagtttttctccagacgaaatacgtcggccaaaagcgc
ttctccttggagggcggcgagtcgctcatccctgcgctcgatgcgatcctcggtggcgcg
gccaatgacgggctgcaccaggtcgccatcggtatggcacaccggggacgcctcaacgtg
ctcaccaacattgctggcaagtcctttggccaggtgttttccgaatttgacggcgtcatg
gaccccaaaaagccgggatcgggtgatgttaagtatcacctcggcacggagggcacttac
actgcggccaacggcgaccaggtgggcgtctatctcgcggccaacccctcccacctcgag
gcggccgacggggtcctcgaaggcgtcgcccgcgccatgcaagaccagctcgacctcgac
gacgacggcgccgcggtcgtccccctgctcatccatggcgatgcggccttttccggtcag
ggcgtcgtcaccgaggtgttgaatctctcccagctgcccgcctaccgcaccggcggcacg
gttcacatcatcgtcaacaaccaaatcggcttcaccacagccccatcgaattcccgatcc
tcgcgctacaccactgacatcgccaagggtctgcaactgccgatattccacgtcaacggt
gacgatcccgaggcggtgtgccgcatggcacgcatggcctacgactaccgcatggaattt
aggaaagacgtcatcctcgatatcatctgctaccgcaagcgtggccacaacgaaggcgac
gacccgtcgatgacgcaacccatcatgtactcgctcgtcgatgagaagcgctccacacgc
cagctctaccgggaggctttgctcggccgcggtgacatctccgacgaagaagcggctaaa
gtcgaacaggactttcacaccctgctcgaacaggccttccagaaagtccgcgagctggaa
aacaaggctgagaccgcgcagggcaaggccgccgatagcctcggcgtgccctcctcccag
caagaagatgccggcacgatggtgggctgggccaccgccgtcgcccccgaggtgcttcaa
cgcattggtaaagcccataccaccccgccagagggcttcaccatccataagaaagtcatg
tcgctctttcacaagcgcaacgccatgactcacgaaggccacatcgactggggctttggc
gaactactcgccttcggctctctcctcatcgaaggcgtaccggttcgcatgtccggccaa
gactcccgccgcggcacgtttacccagcgccacgccgtcgtacacgactcccgcaccggc
gcagagtggacgccgctcatgggcctgaccgaggatcaggcgcgctttaagatatacgac
tcggcgctgtcggagtactcgatcatggccttcgagtacggctattcggttcagcgccca
gacgcgctcgtcctgtgggaagcacagttcggtgattttgccaacggcgcccaaaccgtc
gtcgacgaattcatctcgtctgccgaacaaaagtggcaccaatcttcgtcgatcgtcttg
ctcttgccgcacggctacgaaggccaaggccccgatcactcctccgcccgcattgagcgt
tacttgcagctgtgtgccgaggagaacatggtcgtcgtccagccgaccaccccggcgaac
tacttccacatgttgcgagagcaagcctaccgacgcccgcgcaagccgatgatcgtcttc
tcgcccaagcaactgctgcgccgcaaaggagtcgagtccaccctcgcggaattcacctct
ggcacggtgcgcaaggtgatcggggagacgcgccaactcggcgccgtcgaccgcgtgctc
ctgtgcaccggcagaatctactacgacctgcttgagcagcgcgaaaaggacgacgacgaa
cggacggccatcatccgcgtcgaacagctttacccgaatcccgtggacgaggtgcgggca
gagctggagaagtatccaggtgccgaggtcttctgggttcaggacgagccagccaatcaa
ggtgcatgggcgcactttgctctcgacatgttcccccagctcgatcgcggcatcgcgcgc
atatcgcgccccgccgcggcgtcgacggcggcaggtatggctagcctccatcgcaccgaa
acggccgagttgatgcgccaagcctttgaacggtga
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