Thioalkalivibrio paradoxus: THITH_16310
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Entry
THITH_16310 CDS
T03590
Symbol
metH
Name
(GenBank) B12-dependent methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
tti
Thioalkalivibrio paradoxus
Pathway
tti00270
Cysteine and methionine metabolism
tti00450
Selenocompound metabolism
tti00670
One carbon pool by folate
tti01100
Metabolic pathways
tti01110
Biosynthesis of secondary metabolites
tti01230
Biosynthesis of amino acids
Brite
KEGG Orthology (KO) [BR:
tti00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
THITH_16310 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
THITH_16310 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
THITH_16310 (metH)
09150 Organismal Systems
09154 Digestive system
04980 Cobalamin transport and metabolism
THITH_16310 (metH)
Enzymes [BR:
tti01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
THITH_16310 (metH)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
MtrH
Motif
Other DBs
NCBI-ProteinID:
AHE99594
UniProt:
W0DLX6
LinkDB
All DBs
Position
complement(3498451..3502215)
Genome browser
AA seq
1254 aa
AA seq
DB search
MTDKQPIQQALAERILILDGGMGTMIQEYRLEEADYRGERFADWNSDLKGNNDLLVLTRP
DVIQAIHGDYLEAGADIIETNTFNGTRIAMADYAMEDLVPELNREAARIAREAADAWTAK
TPEKPRFVAGVLGPTNRTASISPDVNDPGYRNVDFDTLVANYRESAAALIEGGVDLLLIE
TVFDTLNAKAAVFAVETLFDETGQRVPVMISGTITDASGRTLSGQTTEAFWNSLRHARPL
SIGLNCALGPKELRAYIEELSRIANTHVSAHPNAGLPNEFGDYDETPEQMAVEIGEWAAS
GFLNIIGGCCGTTPDHIRAIAAAVQAHPPRRMPEIAPACRLSGLEPLNITEDSLFVNVGE
RTNVTGSKRFARLIREEDYETALEVAKDQVENGAQVIDINMDEGMLDSQAAMQRFLNLIA
GEPDIARVPIMIDSSKWEILEAGLKCIQGKGVVNSISLKEGEEKFIEQARLVRRYGAAVI
VMAFDEQGQADTAERKLEICTRAYQILTERIGFPAEDVIFDPNIFAIATGIEEHDNYGVD
FIEATRAIKERLPHALISGGVSNVSFSFRGNEPVREAIHAVFLYHAIHAGMDMGIVNAGQ
LAVYDEIEPELKEAVEDVVLNRRSDATERLLDLAERYRGSGGAAKKEDLEWRSWPVAKRL
EHSLVKGIDSYVVEDTEEARLEAERPIHVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSAR
VMKKAVAHLIPFIEAEKSGCGENNGRILMATVKGDVHDIGKNIVGVVLQCNNFEVIDLGV
MVPAQKILETAREKNVDVIGLSGLITPSLEEMAHVAAEMQRQGFDTPLLIGGATTSRAHT
AVKIEPNYGAGPVVWVKDASRAVGVAQSLISPELKGPYAEKTRAEYAQLRESLAGRKQRI
HWLGLEQARANRPQIDWESYRPVRPRALDPDFPLPPGVTRLQPYGPDSVLLRFDDFDVRE
VARFIDWTPFFHSWQLHAAYPRILDDEVVGAEARKLFDDAQKMLERMIDEGWVRLRGVVG
LFPANSVEFDDIEVYRDEARSEVITRLHHLRQQAQKRRGTPSHSLADFVAPRETGVPDWM
GAFAVSAGGEVDARAKAFEDAHDDYHAILVKSLADRLAEAFAEAMHQRVRREFWGYAPDE
DLGNDDLIQERYTGIRPAPGYPACPEHTEKGLLWELIDPVEHAGMTLTESYAMLPVSAVS
GWYMAHPQSRYFGLGKINRDQVEDYARRKGWSMDEAERWLAPNLGYDPALAESA
NT seq
3765 nt
NT seq
+upstream
nt +downstream
nt
atgacagacaagcaaccgattcaacaagcccttgccgagcgcatcctgatcctggatggc
gggatgggcacgatgatccaggagtaccgcctcgaagaggcggactaccgcggcgagcgt
ttcgccgactggaacagtgatctgaagggcaacaacgacctgctggtgttgacccggccg
gatgtgatccaggcgatccatggcgattacctggaggccggcgccgacatcatcgagacc
aacaccttcaacggcacccgcatcgcaatggccgactatgcgatggaggatctggtgccg
gagctgaaccgagaggccgcgcgcatcgcgcgcgaggccgccgacgcctggaccgcgaag
acgccggagaaaccgcgtttcgtcgccggcgtgctcggaccgaccaaccgcaccgccagc
atctcgccggatgtgaacgacccggggtaccgcaacgtcgatttcgacacgctggtcgcg
aactaccgcgagtccgccgcggcgctgatcgagggcggcgtcgacctgctgctgatcgaa
accgtgttcgacacattgaacgcgaaggccgcggtgtttgcggtggagacgctgttcgac
gaaaccgggcagcgggtaccggtgatgatctccggcaccatcaccgatgcctccgggcgc
accctgtccggacagaccaccgaggcgttctggaacagcctgcgccacgcccggccgctg
tcgatcggcctgaactgcgcgctgggaccgaaggagctgcgcgcctacatcgaggagctt
tcgcggatcgcgaacacccacgtgtccgcgcatccgaacgcgggcctgccgaacgagttc
ggcgactacgacgagaccccggagcagatggcggtcgagatcggcgaatgggcggcgtcg
ggattcctgaacatcatcggcggctgttgcgggaccacgcccgatcacatccgggccatt
gccgcggcggtacaggcgcatcccccgcgccggatgccggagattgcccccgcttgccgg
ctgtcgggcctggaaccgttgaacatcaccgaggattcgctgttcgtgaacgtcggcgag
cggaccaacgtgaccggcagcaagcgctttgcgcggctgatccgcgaggaggactacgag
accgcgctcgaggtcgcgaaggatcaggtcgagaacggcgcgcaggtgatcgacatcaac
atggacgagggcatgctggactcgcaggccgcgatgcagcgtttcctgaacctgatcgcc
ggcgaacccgacatcgcccgggtgccgatcatgatcgactcgtccaagtgggagattctg
gaagcgggcctgaagtgcatccagggcaagggcgtggtgaactcgatctcgctgaaggaa
ggcgaggagaagttcatcgaacaggcgcggctggtgcgccgctacggcgccgcggtgatc
gtgatggcgttcgacgaacagggacaggccgacaccgccgagcgcaagctcgagatctgc
acgcgcgcgtaccagatcctgaccgaacggatcggcttcccggccgaagacgtgatcttc
gacccgaacatcttcgcgatcgcgaccgggatcgaggagcacgacaactacggcgtcgac
ttcatcgaggcgacgcgcgcgatcaaggagcggctgccacatgcactgatctccggcggc
gtgtcgaacgtgtcgttctcgttccgcggcaacgagccggtgcgcgaggcgatccacgcg
gtgttcctgtaccacgcgatccacgcgggcatggacatgggtatcgtcaatgccggccag
ctcgcggtctatgacgaaatcgagccggaactgaaggaggcggtcgaggatgtggtgctg
aaccgccgttccgacgccaccgagcggctgctcgacctcgccgaacgctaccgcggcagc
ggcggcgcggcgaaaaaggaagacctcgaatggcgcagctggccggtggcgaagcgcctc
gagcactcgctggtcaagggcatcgacagctacgtggtcgaggacaccgaggaagcgcgg
ctcgaagccgagcgcccgatccacgtgatcgaggggccgctgatggacggcatgaacgtc
gtcggcgacctgttcggcgagggcaagatgttcctgccgcaggtggtcaagtcggcgcgg
gtgatgaaaaaggcggtggcccacctgatcccgttcatcgaggccgagaagtcgggctgt
ggcgagaacaacggccgcatcctgatggcgacggtgaagggcgacgtgcacgacatcggc
aagaacatcgtcggcgtcgtgctccagtgcaacaacttcgaggtcatcgacctcggcgtg
atggtgccggcgcagaagatcctcgagaccgcgcgcgagaagaacgtcgacgtgatcggg
ctgtccgggctgatcacgccgtcgctcgaggagatggcccacgtcgcagcggaaatgcag
cgccagggcttcgataccccgctgctgatcggcggcgcgaccacgtcgcgcgcccacacc
gcggtgaagatcgagcccaactacggggcgggcccggtggtctgggtcaaggacgcgtcg
cgcgcggtcggcgtggcgcagagcctgatcagccccgagctgaagggtccctacgccgag
aagacccgtgccgagtacgcacagctgcgcgagagtctcgccgggcgcaagcagcgcatc
cactggcttggcctcgaacaggcgcgcgcgaaccggccgcagatcgactgggagtcgtac
cggccggtccggccgcgggcgctggatccggacttcccgctgccgccgggcgtcacgcgg
ctgcagccctacggtccggattcggtattgctgcgcttcgacgatttcgacgtgcgcgag
gtcgcgcgcttcatcgactggacgccgttcttccactcctggcagctgcatgccgcctac
ccgcgcattctcgacgacgaggtggtcggtgccgaagcgcgcaagctgttcgacgacgcg
cagaagatgctggaacggatgatcgacgagggctgggtgcgcctgcgcggcgtggtcgga
ctgttcccggccaacagcgtcgagttcgacgacatcgaggtgtaccgcgacgaggcacgc
agcgaggtgatcacgcgactgcaccacctgcgccagcaggcacagaagcgccgcggcacc
ccgagccattcgctcgccgacttcgtcgcgccgcgcgagaccggcgtgcccgactggatg
ggtgcgttcgcggtcagcgccggcggtgaagtcgatgcccgcgccaaggcgttcgaggat
gcccacgacgactaccacgcgatcctggtgaaaagcctcgcggaccgtctcgcggaggcg
ttcgccgaggcgatgcaccagcgcgtgcggcgcgagttctggggctacgctcccgacgag
gatctcggcaatgacgatctgatccaggaacgctacaccgggatccgcccagccccgggg
tatcccgcctgccccgagcacaccgagaagggtctgctctgggagctgatcgatccggtc
gaacacgcgggaatgacgctgaccgagagctacgcgatgctgccggtctcggcggtgtcc
ggttggtatatggcacatccgcagtcccgttacttcggtctcggcaagatcaaccgcgac
caggtcgaggactacgcccggcgcaagggctggagcatggacgaggccgagcgctggctg
gctccgaacctcggttacgacccggcgctggccgagtctgcctga
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