Xenopus tropicalis (tropical clawed frog): 100495320
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Entry
100495320 CDS
T01011
Symbol
irs1
Name
(RefSeq) insulin receptor substrate 1 isoform X1
KO
K16172
insulin receptor substrate 1
Organism
xtr
Xenopus tropicalis (tropical clawed frog)
Pathway
xtr04068
FoxO signaling pathway
xtr04140
Autophagy - animal
xtr04150
mTOR signaling pathway
xtr04910
Insulin signaling pathway
xtr04920
Adipocytokine signaling pathway
Brite
KEGG Orthology (KO) [BR:
xtr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
100495320 (irs1)
04150 mTOR signaling pathway
100495320 (irs1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100495320 (irs1)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
100495320 (irs1)
04920 Adipocytokine signaling pathway
100495320 (irs1)
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Gene cluster
GFIT
Motif
Pfam:
IRS
PH
PH_11
Motif
Other DBs
NCBI-GeneID:
100495320
NCBI-ProteinID:
XP_002937134
Xenbase:
XB-GENE-478672
UniProt:
A0A6I8SCF3
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Position
5:118796797..118834097
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AA seq
1091 aa
AA seq
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MASPTDPQAQENFSDVRKVGYLRKPKSMHKRFFVLRSASESGLARLEYYENEKKWRHKSG
APKRSIPLESCFNINKRADSKNKHLVALYTKEECFAIAAECEQEQDGWYQALVDLHNRGK
THHQHHNHDGATNGVHDGLNGDDVYGEVTPPGLAFKEVWQVIMKPKGLGQLKNLVGIYRL
CLTNRTISLVKLNSDAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGAGEFWMQVDDSVV
AQNMHETILEAMKALSDEFRPRSKSQSSSNCSNPISVPLRRHHLNHPPPSQVGLNRRART
ESVTATSPAGGVAKHGSSSSFRVRASSDGEGTMSRPASMEGSPVSPSASRAQSHRHRGSS
RLHPPLNHSRSIPMPATRCSPSATSPVSLSSSSTSGHGSTSDCMCPRRSSASVSGSPSDG
GFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPAREEELNNYICMGKSGSHLQRSQQQRYQ
LSRGEEHPDFDKVFRKRTHSSGTSPPTVSHQKTPSQSSIEEYTEMMPAHPVRLTSFRHSA
FVPTYSYPEECLDLHLEGSRANHTDDGYMPMSPGVAPVPTKSNDYMPMSPKSVSAPQQII
NPRRHSAVDSNGYMMMSPSGSCSPDSTNYSKIWTNGTNPKLSIDSIEGKLPCSDYINMSP
ASGSTTSTPPDSYLNSIEESTKPVYSYFSLPRSFKHVHRKSEDGNLRITANSGHNLYTED
SSSSSTSSDSLGGQDPQQPRKGETCIQGKRLTRPTRLSLENSSKASTLPRAREPALPPEP
KSPGEYVNIEFNDKVFSGGLMPSMCPLPFVQSRVVPQRENLSEYMNMDLGVWRAKTSYAS
TSSSSYEPPYKPVSSVCPTETCSSSRPPIRGKTNSRDYMSMQLSALCSDYSQVPPTRITA
KPITLSSNKSNYAEMSSGGVSDNIPAIPQTSNSSLSEASRSSLLGQGSGPSAFTRVSLSP
NRNQSAKVIRAGDPQGRRRHSSETFSSTPTTARVTSGPVSGEDVKRHSSASFENVWLKPG
EIARRDSLQPSDHTHNGLNYIDLDLAKDLSGLDHCNSHQSGVSHPSDDLSTYASITFHKL
EEHRNQAETEE
NT seq
3276 nt
NT seq
+upstream
nt +downstream
nt
atggctagccccacagatccacaggctcaggagaacttttctgatgtcagaaaggtgggc
tatctaaggaaacctaagagcatgcacaagaggttttttgtgctcaggtctgccagtgag
tcaggtttggcccgtttggagtattatgaaaatgagaaaaagtggaggcataagtctggg
gccccaaagaggtcaatccctcttgagagctgctttaatattaacaagagggctgattca
aaaaacaaacatttggttgctttgtacacaaaggaggaatgctttgcaattgctgctgaa
tgtgaacaagaacaggatggttggtatcaggctctagtggatcttcacaaccgtggtaag
acccaccaccaacaccataaccatgacggtgcaaccaatggtgtacatgatggtttaaat
ggagatgacgtttatggggaggttactcctccaggactggccttcaaagaggtatggcag
gtgatcatgaagcccaagggtttagggcaacttaagaatttagttggtatttaccgcctg
tgcctcaccaaccgaacaataagtttggtaaaactgaactctgatgcagccgctgtggta
ttgcaacttatgaatataaggagatgtgggcattcagaaaattttttctttatagaagtg
ggtcgttcagcagtcaccggagctggtgaattctggatgcaagtggatgattcagtagtt
gctcaaaacatgcatgaaaccatactagaagctatgaaagctctgagcgatgaatttcgg
cctcggagtaagagtcagtcttcatctaactgctctaatcctatatctgtacctcttagg
aggcatcaccttaatcatccaccacccagccaggtaggactaaatagaagagctcgtaca
gagagtgttactgccacatcacctgcagggggtgtggcaaagcatggatcatcctcctct
ttcagagtccgggcatctagtgatggagaaggaacaatgtcaaggccagcctccatggaa
gggagcccagtaagtcccagtgctagcagagctcagtcgcaccggcatcggggaagttct
cgacttcacccgcctcttaaccatagtcggtctataccaatgccagcaactcgctgctct
ccatcggctaccagccctgtcagcttgtcctccagtagtaccagtggacatggttccact
tctgattgcatgtgccctcgaagatccagtgcctctgtttctggttcacccagtgatggt
ggttttatttcttcagatgaatatgggtctagcccttgtgactttagaagttcttttcgc
agtgtaaccccagattctttgggccacactccaccagctagggaagaagaactaaataac
tatatttgcatgggcaaatccggtagtcatctccagagaagtcagcagcagaggtaccag
ctaagtcgaggggaagagcaccctgactttgataaggtttttagaaagaggactcactcc
tcaggaacatcacctcctacagtttcacaccagaagacaccatcacagtcctctattgag
gaatatacagagatgatgcctgctcatcctgttcgtttaacatcatttagacattctgca
tttgtacccacctactcctatccagaagagtgcctggacctccatttagagggtagcaga
gctaaccacacagatgacggatacatgcctatgtcacctggtgttgctcctgtgcctaca
aaatcaaatgactatatgcctatgagccctaagagtgtgtcggcccctcaacagatcatt
aacccaagacggcactctgctgtagattcaaatggttatatgatgatgtcacccagtggt
agctgttctccggatagcaccaattacagcaagatatggaccaatggtaccaatccaaag
ttgtccatagatagcattgagggcaaactgccttgcagtgactacattaatatgtctcct
gctagtggctctactacaagcacgcctccagactcttatctgaattctattgaagagtcg
accaagcctgtatattcctacttttccctgcccaggtccttcaaacatgttcacaggaaa
agtgaagatggcaatttgcgcatcactgcaaattctggacataatctatacactgaggac
tcttcctcctcttccacaagcagtgatagtctaggggggcaggaccctcagcagcctaga
aaaggggagacctgcattcaagggaagagattgaccagacccaccaggctttcattggaa
aacagcagtaaggccagcacactgccaagggcgagagaacctgctttgcccccagagcca
aaaagtcctggggagtatgttaatatagagtttaacgacaaggtattttcagggggcttg
atgccttccatgtgtccccttccttttgtgcagagcagagttgtgcctcaaagagagaac
ttgtctgaatacatgaacatggatcttggagtttggagagctaaaacttcctatgcttcc
acctcatcttcatcatatgaaccaccatacaagccggtcagctcagtgtgccctactgaa
acttgcagtagtagtcgaccacctattagaggaaagacaaactcacgagactatatgagc
atgcaacttagtgctctgtgttcagattacagccaagttccacctaccagaataactgcc
aaacccattactctttcttctaataaaagtaattatgcagagatgtcaagtggcggagtt
tctgataatattcctgctattccccaaacttctaactcaagcctatctgaagcatctcgc
tcttcccttttgggccagggctctggccctagcgcctttactcgggtcagtctaagccca
aaccgcaatcagagtgccaaagtcatcagggccggggacccacagggtaggaggaggcac
agctcagagacattctcctctactcctactacagccagagttacttctggcccagtttct
ggggaggatgtcaagagacatagttctgcctcctttgaaaatgtgtggctaaaaccagga
gagattgccaggagagattcccttcagccttctgatcacacacataatggcctgaattat
attgacttagatctagctaaggacttgagtggcctggatcattgcaactcccaccaatct
ggagtaagccacccatcagatgacctgagcacatacgccagcatcactttccacaagcta
gaggagcaccggaatcaggcagaaacagaagaataa
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