KEGG ENZYME: 1.1.1.172

ENZYME: 1.1.1.172

Entry

EC 1.1.1.172                Enzyme

Name

2-oxoadipate reductase;
2-ketoadipate reductase;
alpha-ketoadipate reductase;
2-ketoadipate reductase

Class

Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor

Sysname

2-hydroxyadipate:NAD+ 2-oxidoreductase

Reaction(IUBMB)

2-hydroxyadipate + NAD+ = 2-oxoadipate + NADH + H+ [RN:R01932]

Reaction(KEGG)

Substrate

2-hydroxyadipate [CPD:C02360];
NAD+ [CPD:C00003]

Product

2-oxoadipate [CPD:C00322];
NADH [CPD:C00004];
H+ [CPD:C00080]

History

EC 1.1.1.172 created 1978

Reference

1 [PMID:185965]

Authors

Suda T, Robinson JC, Fjellstedt TA.

Title

Purification and properties of alpha-ketoadipate reductase, a newly discovered enzyme from human placenta.

Journal

Arch Biochem Biophys 176:610-20 (1976)
DOI:10.1016/0003-9861(76)90205-8

Other DBs

ExplorEnz - The Enzyme Database:

IUBMB Enzyme Nomenclature:

ExPASy - ENZYME nomenclature database:

BRENDA, the Enzyme Database:

CAS:	61116-21-0

LinkDB

DBGET integrated database retrieval system