KEGG ENZYME: 1.1.1.308

ENZYME: 1.1.1.308

Entry

EC 1.1.1.308                Enzyme

Name

sulfopropanediol 3-dehydrogenase;
DHPS 3-dehydrogenase (sulfolactate forming);
2,3-dihydroxypropane-1-sulfonate 3-dehydrogenase (sulfolactate forming);
dihydroxypropanesulfonate 3-dehydrogenase;
hpsN (gene name)

Class

Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor

Sysname

(R)-2,3-dihydroxypropane-1-sulfonate:NAD+ 3-oxidoreductase

Reaction(IUBMB)

(R)-2,3-dihydroxypropane-1-sulfonate + 2 NAD+ + H2O = (R)-3-sulfolactate + 2 NADH + 2 H+ [RN:R09545]

Reaction(KEGG)

R09545

Substrate

(R)-2,3-dihydroxypropane-1-sulfonate [CPD:C19675];
NAD+ [CPD:C00003];
H2O [CPD:C00001]

Product

(R)-3-sulfolactate [CPD:C11537];
NADH [CPD:C00004];
H+ [CPD:C00080]

Comment

The enzyme is involved in degradation of (R)-2,3-dihydroxypropanesulfonate.

History

EC 1.1.1.308 created 2011

Pathway

ec00566

Sulfoquinovose metabolism

ec01100

Metabolic pathways

Orthology

K15509

sulfopropanediol 3-dehydrogenase

Genes

AHN:	NCTC12129_02753(hisD_1)

ASUB:

NLZ15_10135(hisD)

VNI:	VIBNI_A1932

VKA:	BTD91_14780(hisD)

VJP:	NP165_13870(hisD)

GHO:	AL542_00750(hisD)

GKD:	K6Q96_22170(hisD)

ELIT:

AB8599_16310(hisD) AB8599_20600(hisD)

NJO:	ABXT42_07745(hisD)

SPIU:

SPICUR_05125

SHAI:

LMH63_05740(hisD)

GAI:	IMCC3135_26035(hpsN_2) IMCC3135_30885(hpsN_3)

HHU:	AR456_20195

HBE:	BEI_0845(hpsN1)

HAF:	C8233_03385(hisD)

HPIS:

P1P91_13840(hisD)

HCAM:

I4484_16810(hisD)

HQN:	M0220_01565(hisD)

HSX:	HNO51_16710(hisD)

COBE:

CLAM6_15020(hisD_2)

COBB:

H2O77_07860(hisD)

COBD:

U0O11_07410(hisD)

COBC:

F8A90_07820(hisD)

PAUR:

FGL86_17225(hisD)

MRZ:	KDW95_18185(hisD)

NJP:	NEJAP_0151 NEJAP_1559

OPE:	PU634_16350(hisD)

TSN:	W908_01090

THIN:

CRN91_00450(hisD)

REU:	Reut_C6092

BURT:

BTHE68_46210(hisD_3)

PCAF:

DSC91_007675

PGIS:

I6I06_21520(hisD)

PEW:	KZJ38_23565(hisD)

PANI:

DCO16_09170(hisD)

PTX:	ABW99_14130

CABK:

NK8_49290(hisD)

AXY:	AXYL_01399(hisD2)

AIS:	BUW96_19425

APES:

FOC84_05690(hisD)

AAEG:

RA224_25910(hisD)

ACHM:

V6V88_04240(hisD)

AVH:	WHX56_11305(hisD)

ACPD:

ACM1PE_02705(hisD)

AKA:	TKWG_18855

AMIM:

MIM_c09530(hisD2)

PARK:

LSG25_14785(hisD)

VEI:

Veis_0769

RTA:	Rta_27270(hisD)

LIH:	L63ED372_00902(hpsN)

ACOM:

CEW83_08425(hisD)

MLN:	A9174_10755

MESU:

LHFGNBLO_006178(hisD)

OST:	ABWH87_16185(hisD)

AMAX:

ABWH92_10520(hisD) ABWH92_10705(hisD)

KMN:	HW532_13965(hisD)

SMD:

Smed_1713

HOAX:

ABWH89_00790(hisD)

OCC:	KMS41_23470(hisD)

BOS:	BSY19_1289(hisD)

STAR:

G3545_11255(hisD)

LNE:	FZC33_14695(hisD)

SNO:

Snov_2959

APRA:

G3A50_21635(hisD)

APOL:

K9D25_16755(hisD)

AQI:	J5J86_01670(hisD)

MMES:

MMSR116_01585(hisD)

MMED:

Mame_04313(hpsN_1)

LABR:

CHH27_12040(hisD)

LABP:

FJ695_27790(hisD)

RPOP:

K1718_07250(hisD)

PAQT:

E8L99_17210(hisD)

SIL:	SPO0594(hpsN) SPO0981

RUA:	D1823_05095(hisD)

RUT:	FIU92_07910(hpsN1)

RCON:

K3740_11140(hisD)

RUY:	NOR97_07860(hisD)

JAN:

Jann_1398

JOV:	P8627_13595(hisD)

RDE:	RD1_3808(hisD)

RLI:	RLO149_c006370(hisD3)

RPON:

G3256_03870(hisD)

RFU:	ROLI_015440(hpsN_2)

RALG:

AB4K19_002705(hisD)

DSH:	Dshi_2034(hisD2)

PGA:	PGA1_c07750(hisD1) PGA1_c25490(hisD2)

PGL:	PGA2_c07530(hisD2)

PGD:

Gal_02716

PPIC:

PhaeoP14_00696(hisD1)

PHQ:	D1820_16950(hisD)

PBRZ:

ACEQPH_14475(hisD)

OAT:	OAN307_c48490(hisD3)

OAR:	OA238_c24160(hisD1) OA238_c29640(hisD2) OA238_c48370(hisD4)

OTM:	OSB_32490(hpsN)

OCT:	FTO60_13760(hisD)

LMD:	METH_14695 METH_22265

LEJ:	ETW24_02325(hisD) ETW24_15625(hisD)

LAQU:

R2C4_00650(hisD) R2C4_03535(hisD)

LEV:	ETW23_01060(hisD) ETW23_14945(hisD)

LCAE:

K3721_13835(hisD) K3721_20595(hisD)

LEIM:

K3557_02315(hisD)

MALG:

MALG_00809 MALG_01230

YPAC:

CEW88_04375(hisD)

YAN:	AYJ57_15325

SUAM:

BOO69_14470

SULZ:

C1J03_11915(hisD)

SULI:

C1J05_06910(hisD) C1J05_16090(hisD)

SULD:

B5M07_10355

SMED:

JNX03_12640(hisD) JNX03_17100(hisD) JNX03_17125(hisD)

SINL:

DSM14862_01599(hpsN)

SUSQ:

K3756_18805(hisD)

SRHD:

AB4X18_04210(hisD)

SPSE:

SULPSESMR1_02367(hpsN)

TATE:

ACMHLQ_06845(hisD) ACMHLQ_22880(hisD)

TATY:

ACERHN_13735(hisD) ACERHN_18655(hisD)

RMM:	ROSMUCSMR3_00082(hpsN) ROSMUCSMR3_02361(hpsN)

ROK:	RAK1035_0822 RAK1035_2931

RID:	RIdsm_00494(hpsN)

ROM:	EI983_02800(hisD) EI983_18900(hisD)

ROH:	FIU89_02610(hpsN1) FIU89_13955(hpsN2)

RPEL:

N7U68_06845(hisD)

RPHC:

RZ517_05485(hisD)

RRL:	RZS32_001925(hisD)

AHT:	ANTHELSMS3_04524

SAGU:

CDO87_14620(hisD) CDO87_18520(hisD)

SSTL:

ABFK29_18935(hisD)

SAGZ:

QNI11_12995(hisD) QNI11_17075(hisD)

THAA:

CFI11_07280(hisD)

MALU:

KU6B_37700(hisD_1) KU6B_40350(hisD_3)

LALG:

LentiSH36_00120(hisD2) LentiSH36_02117(hisD1)

TRY:	QF118_08585(hisD)

MARU:

FIU81_03585(hpsN)

ASCA:

QEZ52_08685(hisD) QEZ52_21985(hisD)

ACLD:

ACIRQ6_09285(hisD)

SEOH:

ACMUJL_06445(hisD)

MATG:

ACMVPR_03685(hisD)

BOO:	E2K80_12245(hisD) E2K80_12270(hisD)

NER:	NeNHUV3_21870(hpsN_3)

FYT:	QF092_15225(hisD)

PYE:	A6J80_16410(hisD)

PZH:	CX676_13155(hisD)

PARO:

CUV01_13375(hisD)

PMEH:

JWJ88_09100(hisD)

PSEW:

JHW44_16745(hisD) JHW44_18530(hisD)

PALP:

JHW40_23575(hisD)

PDIM:

PAF18_09285(hisD)

PFEO:

E3U26_14735(hisD)

PHOI:

ACLISE_13710(hisD)

PTP:	RCA23_c21930(hisD2)

RSU:	NHU_04453(hisD)

THW:	BMG03_09575

YPHY:

AABB29_05425(hisD)

YAG:	AABB28_11515(hisD)

YRH:	AABB31_17605(hisD)

GEH:	HYN69_00370(hisD)

TAW:	EI545_04905(hisD) EI545_14725(hisD)

SEDI:

EBB79_14275(hisD)

PAED:

G5B38_17045(hisD)

POZ:	I0K15_20480(hisD)

CACT:

HZ995_04845(hisD) HZ995_10075(hisD)

THAS:

C6Y53_06700(hisD)

GCE:	KYE46_06510(hisD) KYE46_13960(hisD)

GYJ:	AADW23_16985(hisD)

AMYL:

QBD29_04440(hisD)

AMAQ:

GO499_11575(hisD)

RHOC:

QTA57_05990(hisD)

RBG:	BG454_15370(hisD)

BOSG:

GKR98_10185(hisD)

MANH:

LA6_000072(hpsN_1)

FAQ:	G5B39_15400(hisD)

NRE:	BES08_18880

NOR:	FA702_20105(hisD)

NOG:	GKE62_11150(hisD)

NOVB:

ACFFDA_09410(hisD)

SPCL:

F9288_09015(hisD)

SRF:	LHU95_15400(hisD)

AALU:

ABWI00_19820(hisD)

PUB:	SAR11_0801(hisD2)

PEG:	E5R92_01975(hisD)

PELA:

B5L73_04585

APM:	HIMB5_00003860

APB:	SAR116_2138

POND:

ABXT40_08975(hisD)

DFI:	AXF13_09680

TMUR:

JBF11_07045(hisD)

DEO:	CAY53_05305

DAT:	HRM2_03140(hisD1)

DALK:

DSCA_18210(hisD_1)

DEK:	DSLASN_21760(hisD_1) DSLASN_21880(hisD_2)

MGO:	AFA91_19790

BKR:	AAFP32_01840(hisD)

AMAZ:

LUW76_20245(hisD)

» show all

Reference

1 [PMID:20150239]

Authors

Mayer J, Huhn T, Habeck M, Denger K, Hollemeyer K, Cook AM

Title

2,3-Dihydroxypropane-1-sulfonate degraded by Cupriavidus pinatubonensis JMP134: purification of dihydroxypropanesulfonate 3-dehydrogenase.

Journal

Microbiology 156:1556-64 (2010)
DOI:10.1099/mic.0.037580-0

Sequence

[reu:Reut_C6092]

Other DBs

ExplorEnz - The Enzyme Database:

1.1.1.308

IUBMB Enzyme Nomenclature:

1.1.1.308

ExPASy - ENZYME nomenclature database:

1.1.1.308

BRENDA, the Enzyme Database:

1.1.1.308

LinkDB

DBGET integrated database retrieval system