KEGG   ENZYME: 1.1.1.311
Entry
EC 1.1.1.311                Enzyme                                 
Name
(S)-1-phenylethanol dehydrogenase;
PED
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
(S)-1-phenylethanol:NAD+ oxidoreductase
Reaction(IUBMB)
(S)-1-phenylethanol + NAD+ = acetophenone + NADH + H+ [RN:R05352]
Reaction(KEGG)
R05352
Substrate
(S)-1-phenylethanol [CPD:C11348];
NAD+ [CPD:C00003]
Product
acetophenone [CPD:C07113];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
The enzyme is involved in degradation of ethylbenzene.
History
EC 1.1.1.311 created 2011
Pathway
ec00642  Ethylbenzene degradation
ec01120  Microbial metabolism in diverse environments
Orthology
K14746  (S)-1-phenylethanol dehydrogenase
Genes
EBA: c1A58(ped)
ABRE: pbN1_00010(ped)
Reference
1  [PMID:11479712]
  Authors
Kniemeyer O, Heider J
  Title
(S)-1-phenylethanol dehydrogenase of Azoarcus sp. strain EbN1, an enzyme of anaerobic ethylbenzene catabolism.
  Journal
Arch Microbiol 176:129-35 (2001)
DOI:10.1007/s002030100303
  Sequence
[eba:c1A58]
Reference
2  [PMID:16388583]
  Authors
Hoffken HW, Duong M, Friedrich T, Breuer M, Hauer B, Reinhardt R, Rabus R, Heider J
  Title
Crystal structure and enzyme kinetics of the (S)-specific 1-phenylethanol dehydrogenase of the denitrifying bacterium strain EbN1.
  Journal
Biochemistry 45:82-93 (2006)
DOI:10.1021/bi051596b
  Sequence
[eba:c1A58]
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.311
IUBMB Enzyme Nomenclature: 1.1.1.311
ExPASy - ENZYME nomenclature database: 1.1.1.311
UM-BBD (Biocatalysis/Biodegradation Database): 1.1.1.311
BRENDA, the Enzyme Database: 1.1.1.311
LinkDB

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