Entry |
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Name |
UDP-N-acetyl-D-mannosamine dehydrogenase;
UDP-ManNAc 6-dehydrogenase;
wecC (gene name)
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Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
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Sysname |
UDP-N-acetyl-alpha-D-mannosamine:NAD+ 6-oxidoreductase
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Reaction(IUBMB) |
UDP-N-acetyl-alpha-D-mannosamine + 2 NAD+ + H2O = UDP-N-acetyl-alpha-D-mannosaminuronate + 2 NADH + 2 H+ [RN: R03317]
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Reaction(KEGG) |
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Substrate |
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Product |
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Comment |
Part of the pathway for acetamido sugar biosynthesis in bacteria and archaea. The enzyme has no activity with NADP+.
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History |
EC 1.1.1.336 created 2012
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Pathway |
ec00520 | Amino sugar and nucleotide sugar metabolism |
ec00541 | O-Antigen nucleotide sugar biosynthesis |
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Orthology |
K02472 | UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase |
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Genes |
ECOO: | ECRM13514_4847(wecC) |
ECOH: | ECRM13516_4632(wecC) |
ELR: | ECO55CA74_21980(wecC) |
ECW: | EcE24377A_4298(wecC) |
EDJ: | ECDH1ME8569_3669(rffD) |
ECOI: | ECOPMV1_04120(ywqF) |
ERUY: | OSH18_12685(wecC) OSH18_16820(wecC) |
SEM: | STMDT12_C40750(wecC) |
SETC: | CFSAN001921_20825(wecC) |
SEEN: | SE451236_01295(wecC) |
SENH: | CFSAN002069_12435(wecC) |
SEEH: | SEEH1578_05720(wecC) |
SENJ: | CFSAN001992_14055(wecC) |
SEEC: | CFSAN002050_02490(wecC) |
SEEB: | SEEB0189_022730(wecC) |
SENC: | SEET0819_03460(wecC) |
REE: | electrica_04900(wbpA) |
RTG: | NCTC13098_07038(ywqF) |
CIB: | HF677_009120(wecC) HF677_024375(wecC) |
CLAP: | NCTC11466_04439(ywqF) |
KIE: | NCTC12125_03610(ywqF) |
AHN: | NCTC12129_04767(rffD) |
METY: | MRY16398_54540(wecC) |
PSHI: | SAMEA2665130_3012(ywqF) |
SMW: | SMWW4_v1c01740(rffD) |
SERS: | SERRSCBI_00720(wecC) |
SFJ: | SAMEA4384070_0129(ywqF) |
SOF: | NCTC11214_01910(ywqF) |
SSAR: | SSARUM_000125(wecC) |
PAQU: | DMB82_0019235(wecC) |
PARL: | PEC302110_01570(wecC) |
DIC: | Dpoa569_000258(wecC) |
TPTY: | NCTC11468_03537(ywqF) |
PHEI: | NCTC12003_03736(ywqF) |
PRJ: | NCTC6933_03751(ywqF_2) |
LRI: | NCTC12151_03590(ywqF) |
MHX: | MHH_c03490(wecC1) MHH_c05370(wecC2) |
MHAE: | F382_08115(wecC) F382_09220(wecC) |
MHAO: | J451_07015(wecC) J451_07860(wecC) |
MHAL: | N220_13005(wecC) N220_13930(wecC) |
MHAQ: | WC39_00350 WC39_01260 |
MHAY: | VK67_00355 VK67_01265 |
ALIG: | NCTC10568_01906(wecC) |
VAU: | VANGNB10_cI0797(epsD) |
VPL: | SA104470976_01847(wecC) |
PMUD: | NCTC8068_01773(ywqF) |
PTRT: | HU722_0021405(wecC) |
MSHE: | MAALD49_25750(wecC) |
SCAA: | TUM17387_14460(wecC) |
PIA: | PI2015_0469 PI2015_1229 |
PSAZ: | PA25_03930(wecC_1) PA25_26180(wecC_2) |
PSYM: | J1N51_03945(wecC) J1N51_10190(wecC) |
PSY: | PCNPT3_01335 PCNPT3_05450(wecC) PCNPT3_11745(wecC) |
MVB: | MJO52_04365(wecC) MJO52_04440(wecC) |
LLG: | 44548918_01791(capL) |
TFRI: | Thiofri_04845(wbpA_2) |
GAI: | IMCC3135_22240(wecC) |
ALCA: | ASALC70_04080(wecC) |
MARS: | A8C75_00925 A8C75_08330 |
NJP: | NEJAP_0904 NEJAP_2311 |
NZO: | SAMEA4504057_2343(ywqF) |
NCI: | NCTC10296_00791(ywqF) |
BPY: | Bphyt_4052 Bphyt_6019 |
PDIO: | PDMSB3_0845.1(rffD) |
BUO: | BRPE64_ECDS01920(rffD) |
BOZ: | DBV39_01230 DBV39_10665 |
RBS: | RHODOSMS8_03378(wecC) |
BCAN: | BcanWSM471_10880(wecC) |
PSEW: | JHW44_14045(wecC) JHW44_15120(wecC) |
LVS: | LOKVESSMR4R_01585(wecC) |
SMY: | BJP26_13980 BJP26_18185 |
SBIN: | SBA_ch1_26590(wecC) |
SYB: | TZ53_16410 TZ53_24410 |
SPAG: | sphantq_03679(wecC_1) sphantq_04711(wecC_2) |
SFLA: | SPHFLASMR4Y_00279(wecC) |
SLAA: | EUU25_06570 EUU25_12190 |
PALG: | HFP57_13670 HFP57_17450(wecC) |
CAEN: | K5X80_02055(wecC) K5X80_04205(wecC) |
SKT: | IGS68_21260(wecC) IGS68_23020 |
SMUC: | JL100_004875(wecC) JL100_024640 |
SROE: | JL101_002005 JL101_004775(wecC) |
CDEV: | CIGN_0986 CIGN_0988 |
BSON: | S101395_00581(wecC) |
BFD: | NCTC4823_03718(ywqF) |
BMEG: | BG04_2122(wecC) BG04_3410 |
CSPG: | LS684_18990 LS684_20705 |
OCN: | CUC15_16655 CUC15_17315 |
PCAL: | BV455_01995(wbpA_1) BV455_02098(wbpA_2) |
HHD: | HBHAL_4426 HBHAL_4469 |
HMN: | HM131_04910 HM131_05060 |
APAK: | AP3564_03730 AP3564_07560 |
BMUR: | ABE28_015875 ABE28_020665 |
BLEN: | NCTC4824_03797(ywqF) |
SAX: | USA300HOU_0177(cap5O) |
SAA: | SAUSA300_0166(cap5O) |
SUJ: | SAA6159_00147(cap8O) |
SUK: | SAA6008_00141(cap5O) |
SUX: | SAEMRSA15_01290(capO) |
SUF: | SARLGA251_01370(capO) |
SAUT: | SAI1T1_2001180(capO) |
SAUJ: | SAI2T2_1001180(capO) |
SAUK: | SAI3T3_1001180(capO) |
SAUQ: | SAI4T8_1001180(capO) |
SAUV: | SAI7S6_1001180(capO) |
SAUW: | SAI5S5_1001170(capO) |
SAUX: | SAI6T6_1001180(capO) |
SAUY: | SAI8T7_1001180(capO) |
SDP: | NCTC12225_01989(ywqF) |
SSH: | NCTC13712_00118(ywqF) |
SSTE: | SAMEA4384403_1794(ywqF) |
MVT: | I6J10_00280 I6J10_02395 |
MEQU: | KFV11_03770 KFV11_10285 |
MCAK: | MCCS_08760(wbpA_1) MCCS_08960(wbpA_2) |
LWI: | UE46_00750 UE46_00860 UE46_04145 UE46_15790 UE46_15905 |
LGZ: | NCTC10812_00284(ywqF_1) NCTC10812_01722(ywqF_3) |
LNW: | OTR81_04185 OTR81_05610 OTR81_06550 OTR81_06690 OTR81_08895 |
EXI: | A0126_04045 A0126_12815 |
BHUI: | LOK74_08105 LOK74_13955 |
PDEC: | H1Q58_12370 H1Q58_12935 |
CPRF: | K7H06_08955 K7H06_20415(wecC) |
CBAR: | PATL70BA_1478(wecC) |
PSOR: | RSJ16_11035 RSJ16_13895 |
TGC: | L0P85_03930 L0P85_15630 |
TPET: | TPHSE_09980(wecC_1) TPHSE_34750(wecC_2) |
EAC: | EAL2_c18790(wecC) EAL2_c20050(epsD) |
ERL: | AOC36_01340 AOC36_08635 AOC36_08715 |
MMAE: | MMARE11_22310(udgL) |
MBAI: | MB901379_02147(wbpA) |
MPHL: | MPHLCCUG_01587(ywqF_2) |
CMIN: | NCTC10288_00689(ywqF) |
CRL: | NCTC7448_00195(ywqF) |
CCYS: | SAMEA4530656_0554(ywqF) |
SAMB: | SAM23877_6664(cgc8) |
AUW: | AURUGA1_01214(algD_1) AURUGA1_01237(algD_2) |
AAGI: | NCTC2676_1_01726(ywqF) |
MICK: | B1A86_00004410(wecC) |
CMUA: | P8192_00855(wecC) P8192_06550(wecC) |
OFA: | NF556_19770(wecC) NF556_19800(wecC) |
TLA: | TLA_TLA_01802(wecC_2) |
MCAB: | HXZ27_03435 HXZ27_11050 |
ACTE: | ACTI_40850(wecC) ACTI_47310 |
PLAB: | C6361_08575 C6361_10790 |
PLAT: | C6W10_05145 C6W10_07885 |
PFLA: | Pflav_007290(wecC) Pflav_084300 |
PSUU: | Psuf_046950 Psuf_064300 |
DVC: | Dvina_17990 Dvina_41910 |
DACT: | KZZ52_46170 KZZ52_48025 |
AHW: | NCTC11636_02609(tuaD_2) |
AVC: | NCTC10951_00252(tuaD_1) |
FLH: | EJ997_03200 EJ997_03215 |
BALA: | DSM104299_05362(wbpA_3) |
PSUB: | Pelsub_P0632 Pelsub_P1083 |
LEK: | hrd7_02570 hrd7_18340 |
NPY: | NPRO_08880 NPRO_20290 |
TNR: | Thena_0400 Thena_0841 |
SDYN: | Mal52_17930(wbpA_1) |
CCOS: | Pan44_21500(wbpA_2) |
FVA: | FV113G1_10280(wbpA) FV113G1_25480(wecC) |
BTHO: | Btheta7330_00140(wbpA) |
BFS: | BF9343_0708 BF9343_4190 |
BFG: | BF638R_1081 BF638R_4463 |
BFB: | VU15_04735 VU15_20910 |
BHL: | Bache_0857 Bache_2457 |
BCEL: | BcellWH2_00700(wbpA_3) |
BEG: | INE88_00277(wecC_1) INE88_00287(wecC_2) INE88_00333(wecC_3) |
BNO: | K8P02_02090 K8P02_09470(wecC) K8P02_11355(wecC) K8P02_17520(wecC) |
BFC: | BacF7301_20330(wecC) |
BSAL: | K6V25_03385(wecC) K6V25_17805(wecC) |
PCAG: | NCTC12856_02047(ywqF_2) |
PARC: | CI960_03225 CI960_12165 |
PGOL: | K6V26_04055(wecC) K6V26_13205(wecC) |
PFAI: | NXY11_03265(wecC) NXY11_11800(wecC) NXY11_13245(wecC) |
BUY: | D8S85_03840 D8S85_16515 D8S85_20570 |
BFH: | F1611_00700(wecC) F1611_02890(wecC) |
FLL: | EI427_04730 EI427_15485 |
CLY: | Celly_1356 Celly_2630 |
AEQU: | QCQ61_04440(wecC) QCQ61_13575(wecC) |
AALG: | AREALGSMS7_03258(wecC) |
KOS: | KORDIASMS9_01183(wecC) |
KAN: | IMCC3317_28500(wecC) |
SPON: | HME9304_01538(wecC) |
PROC: | Ptc2401_01386(wbpA_2) |
MEIS: | PXD04_03060 PXD04_05750 |
METV: | K4897_04805 K4897_08860 |
MEME: | HYG87_02005 HYG87_03510 |
MLS: | MSLAZ_2865 MSLAZ_2996 |
METM: | MSMTP_0135 MSMTP_0213 |
MHOR: | MSHOH_0195 MSHOH_0207 |
MEM: | Memar_1606 Memar_2304 |
MBG: | BN140_0823 BN140_2094 BN140_2394 |
MEMA: | MMAB1_1083 MMAB1_2730 |
MCHK: | MchiMG62_00380 MchiMG62_18090 |
MSUM: | OH143_02240 OH143_05805 |
MAQE: | RJ40_07050 RJ40_10370 |
MFK: | E2N92_02830 E2N92_07205 E2N92_10560 |
MESB: | L1S32_02340 L1S32_02555 |
MFO: | Metfor_0443 Metfor_1417 |
MPD: | MCP_0776 MCP_0840 MCP_0889 MCP_2544 |
HLU: | LT972_05240 LT972_06560 LT972_06925 |
HDO: | MUK72_10330 MUK72_10815 |
HALX: | M0R89_17765 M0R89_20540 |
HAYC: | NGM10_11730 NGM10_15370 |
HARA: | AArcS_1799(wecC2) AArcS_1808(wecC3) |
HHI: | HAH_0357 HAH_5156(ugd2) |
HHN: | HISP_01870 HISP_18950 |
HAB: | SG26_09680 SG26_17300 |
HALZ: | E5139_03720 E5139_13270 |
HAZP: | GBQ70_03720 GBQ70_13285 |
HALI: | BV210_17865 BV210_19380 |
SSAI: | N0B31_19260 N0B31_19715 |
HLN: | SVXHx_2512(wecC) SVXHx_4251(wecC) |
HME: | HFX_6134(wecC) HFX_6230(wecC) |
HGI: | ABY42_17040 ABY42_18110 |
HLS: | KU306_15930 KU306_17570 |
HALG: | HUG10_07505 HUG10_20645 |
NVR: | FEJ81_06150 FEJ81_07030 FEJ81_21645 |
NAY: | HYG81_03570 HYG81_03970 |
HRU: | Halru_1008 Halru_1610 |
SAWL: | NGM29_07120 NGM29_09600 |
HALV: | NGM15_01815 NGM15_15645 NGM15_16315 |
HLC: | CHINAEXTREME14375 CHINAEXTREME16560 |
NAJ: | B1756_09715 B1756_10920 |
NVN: | NVIE_010320 NVIE_023860 |
TAA: | NMY3_01400(wbpA_1) NMY3_01887(wbpA_2) NMY3_02476(wbpA_4) |
NFN: | NFRAN_0021(wbpA) NFRAN_2013(wbpA) NFRAN_2294 NFRAN_2698(wbpA) |
BARB: | AOA66_0575(wecC_1) AOA66_1378(wecC_2) |
LOKI: | Lokiarch_37550(wecC) |
» show all
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Reference |
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Authors |
Namboori SC, Graham DE |
Title |
Acetamido sugar biosynthesis in the Euryarchaea. |
Journal |
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Sequence |
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Other DBs |
ExPASy - ENZYME nomenclature database: | 1.1.1.336 |
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LinkDB |
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