KEGG   ENZYME: 1.1.1.368
Entry
EC 1.1.1.368                Enzyme                                 
Name
6-hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
6-hydroxycyclohex-1-ene-1-carbonyl-CoA:NAD+ 6-oxidoreductase
Reaction(IUBMB)
6-hydroxycyclohex-1-ene-1-carbonyl-CoA + NAD+ = 6-oxocyclohex-1-ene-1-carbonyl-CoA + NADH + H+ [RN:R05581]
Reaction(KEGG)
R05581
Substrate
6-hydroxycyclohex-1-ene-1-carbonyl-CoA [CPD:C06749];
NAD+ [CPD:C00003]
Product
6-oxocyclohex-1-ene-1-carbonyl-CoA [CPD:C09821];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
The enzyme participates in the central benzoyl-CoA degradation pathway of some anaerobic bacteria such as Thauera aromatica.
History
EC 1.1.1.368 created 2014
Pathway
ec00362  Benzoate degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K07538  6-hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase
Genes
SHDSUTH_01655(had)
EBAebA5297(had)
ABREpbN1_04260(had)
APETToN1_48990(had)
AZAAZKH_2148(had_bzdX)
AZIAzCIB_1613 AzCIB_4485
AZDCDA09_12105(had) CDA09_21785(had)
TMZTmz1t_2954 Tmz1t_4042
TCLTchl_2144 Tchl_3418
TAKTharo_1302 Tharo_3372
DDZDSYM_16340
GMEGmet_2151(bamQ)
GEMGM21_2823
GPIGPICK_09520
GEOGeob_0097(bamQ)
GBMGbem_1431(bamQ)
GBNGEOBRER4_29910(adhA)
GSUBKP001_01870(had)
DTOTOL2_C03830(had)
DOVDSCO28_32420
DWDDSCW_14380
DALKDSCA_13410
DMMdnm_057830(had)
SATSYN_01655
DTIDesti_3055
RVARvan_0034
BLAGBLTE_16540
MAGamb2144
MAGXXM1_2899
MAGNWV31_08585
DGIDesgi_1969
 » show all
Reference
1  [PMID:10406950]
  Authors
Laempe D, Jahn M, Fuchs G
  Title
6-Hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase and 6-oxocyclohex-1-ene-1-carbonyl-CoA hydrolase, enzymes of the benzoyl-CoA pathway of anaerobic aromatic metabolism in the denitrifying bacterium Thauera aromatica.
  Journal
Eur J Biochem 263:420-9 (1999)
DOI:10.1046/j.1432-1327.1999.00504.x
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.368
IUBMB Enzyme Nomenclature: 1.1.1.368
ExPASy - ENZYME nomenclature database: 1.1.1.368
BRENDA, the Enzyme Database: 1.1.1.368
LinkDB

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