Entry
Name
dihydroanticapsin dehydrogenase;
BacC;
ywfD (gene name)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
L-dihydroanticapsin:NAD+ oxidoreductase
Reaction(IUBMB)
L-dihydroanticapsin + NAD+ = L-anticapsin + NADH + H+ [RN:
R10917 ]
Reaction(KEGG)
Substrate
Product
Comment
The enzyme, characterized from the bacterium Bacillus subtilis, is involved in the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin.
History
EC 1.1.1.385 created 2015
Pathway
ec00998 Biosynthesis of various antibiotics
ec01110 Biosynthesis of secondary metabolites
Orthology
K19548 dihydroanticapsin dehydrogenase
Genes
ALAM : RT761_01341(bacC_5)
BAZ : BAMTA208_19090(bacC)
MAUU : NCTC10437_02787(cpnA_3)
SXT : KPP03845_100609(bacC_1) KPP03845_106164(bacC_4)
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Taxonomy
Reference
Authors
Parker JB, Walsh CT
Title
Action and timing of BacC and BacD in the late stages of biosynthesis of the dipeptide antibiotic bacilysin.
Journal
Other DBs
ExPASy - ENZYME nomenclature database: 1.1.1.385
LinkDB
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