Entry |
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Name |
4-hydroxybutyrate dehydrogenase;
gamma-hydroxybutyrate dehydrogenase
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Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
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Sysname |
4-hydroxybutanoate:NAD+ oxidoreductase
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Reaction(IUBMB) |
4-hydroxybutanoate + NAD+ = succinate semialdehyde + NADH + H+ [RN: R01644]
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Reaction(KEGG) |
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Substrate |
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Product |
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History |
EC 1.1.1.61 created 1965
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Pathway |
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Orthology |
K00043 | 4-hydroxybutyrate dehydrogenase |
K08318 | 4-hydroxybutyrate dehydrogenase / sulfolactaldehyde 3-reductase |
K18120 | 4-hydroxybutyrate dehydrogenase |
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Genes |
EDJ: | ECDH1ME8569_3753(yihU) |
ECOI: | ECOPMV1_04237(garR_4) |
AHN: | NCTC12129_04955(garR_2) |
LRI: | NCTC12151_00811(Hgd) |
HALO: | BWR19_00250 BWR19_04415 |
HPRO: | LMS44_02965 LMS44_19180 |
HAAH: | HALA3H3_200101 HALA3H3_520002 |
HTT: | HZS52_00870 HZS52_09090 |
RSO: | RSc1771(gbd1) RSp0986(gbd2) |
RPU: | CDC45_09125 CDC45_22570 |
RNC: | GO999_08490 GO999_18950 |
RSL: | RPSI07_1814 RPSI07_mp0978 |
RSN: | RSPO_c01807(gbd1) RSPO_m01535(gbd2) |
RSM: | CMR15_11780 CMR15_mp20069 |
RSY: | RSUY_19640(dhaT_1) RSUY_45330(dhaT_2) |
RSG: | JK151_12230 JK151_19010 |
RPJ: | N234_07690 N234_11110 N234_25710 |
CNC: | CNE_1c15720(gbd1) CNE_2c21420(dhaT) |
CUH: | BJN34_07770 BJN34_35670 BJN34_36185 |
REU: | Reut_A1418 Reut_C6426 |
CTI: | RALTA_A1479(gbd1) RALTA_A1654 |
COX: | E0W60_17505 E0W60_19295 E0W60_28535 |
CUK: | KB879_07945 KB879_16100 KB879_34200 |
BPM: | BURPS1710b_1823(gbd1) |
BYI: | BYI23_C013470 BYI23_D009270 |
BUE: | BRPE67_CCDS13020 BRPE67_DCDS11290 |
BUM: | AXG89_00640 AXG89_13410 |
BUI: | AX768_07270 AX768_10380 |
BURT: | BTHE68_47650(gbd_1) BTHE68_67010(gbd_2) |
BCAI: | K788_0004323 K788_0005638 |
PHS: | C2L64_05070 C2L64_35875 |
PTER: | C2L65_04865 C2L65_18360 |
PDIO: | PDMSB3_2375.1(yihU) PDMSB3_3115 |
PLAD: | PPGU16_09910 PPGU16_39790(gbd) |
BUO: | BRPE64_DCDS02300 BRPE64_DCDS08060 |
CABK: | NK8_43040 NK8_61790 |
BBH: | BN112_1980(gbd) BN112_4333 |
BBM: | BN115_1435(gbd) BN115_3759 |
BBX: | BBS798_1441(gbd) BBS798_3863 |
BGV: | CAL12_07435 CAL12_14520 |
AIS: | BUW96_16295 BUW96_19440 |
AAEG: | RA224_25925 RA224_26385 |
POLL: | OEG81_00905 OEG81_01465 OEG81_17500 |
PACR: | FXN63_01020 FXN63_12020 |
RHY: | RD110_09325 RD110_14010 |
ACK: | C380_00980 C380_10655 |
ACRA: | BSY15_1622 BSY15_3223 |
ACIP: | CBP36_00930 CBP36_11490 |
ACIS: | CBP35_07440 CBP35_18025 |
ARAD: | KI609_11230 KI609_19130 |
ATEM: | PQV96_09560 PQV96_20325 |
CTT: | CtCNB1_1590 CtCNB1_3095 |
CTEZ: | CT3_22930 CT3_33130(yihU) |
LIM: | L103DPR2_01788(dhaT_2) |
LIH: | L63ED372_01374(dhaT) |
HTN: | KI616_03440 KI616_13470 |
DIH: | G7047_09480 G7047_12135 |
DAER: | H9K75_01440 H9K75_23190 |
ETB: | N7L95_02510 N7L95_14505 |
URU: | DSM104443_03117(dhaT_2) |
RFV: | RFYW14_00857 RFYW14_03906 |
BVES: | QO058_20595 QO058_26795 |
MAQU: | Maq22A_1p34110(eutG) Maq22A_c07255(eutG) |
CHEL: | AL346_05120 AL346_06850 AL346_16010 |
PSIN: | CAK95_05960 CAK95_11375 |
PPHR: | APZ00_11925 APZ00_16710 |
PHR: | C6569_16040 C6569_18140 |
TSV: | DSM104635_00837(gbsB) |
SHUM: | STHU_13550 STHU_22030 |
SVC: | STVA_09960 STVA_25540(garR) |
STEL: | STAQ_13280(gbd) STAQ_18190 |
HADH: | FRZ61_10700 FRZ61_45740 |
NACI: | NUH88_15765 NUH88_17465 |
CPAS: | Clopa_4032 Clopa_4274 |
CPAT: | CLPA_c06290 CLPA_c39010 |
CPAE: | CPAST_c06290 CPAST_c39010 |
CTAG: | LL095_06185 LL095_09940 |
FPLA: | A4U99_06825 A4U99_13645 A4U99_15805 A4U99_16840 |
AGAT: | RWV98_04250 RWV98_06160 RWV98_10270 RWV98_11710 RWV98_11945 |
INT: | RX717_00900 RX717_03940 RX717_07990 |
WHJ: | H9Q79_06935 H9Q79_10125 |
PDF: | CD630DERM_23380(4hbD) |
RHOM: | FRIFI_0256 FRIFI_1669 |
SPOA: | EQM13_06730 EQM13_09885 |
PCRE: | NCTC12858_01804(adhB) |
PCAG: | NCTC12856_01247(eutG) |
» show all
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Reference |
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Authors |
NIRENBERG MW, JAKOBY WB. |
Title |
Enzymatic utilization of gamma-hydroxybutyric acid. |
Journal |
J Biol Chem 235:954-60 (1960) |
Other DBs |
ExplorEnz - The Enzyme Database: | 1.1.1.61 |
ExPASy - ENZYME nomenclature database: | 1.1.1.61 |
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LinkDB |
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