| Entry |
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| Name |
(S,S)-butanediol dehydrogenase;
L-butanediol dehydrogenase;
L-BDH;
L(+)-2,3-butanediol dehydrogenase (L-acetoin forming);
(S)-acetoin reductase [(S,S)-butane-2,3-diol forming]
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| Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
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| Sysname |
(S,S)-butane-2,3-diol:NAD+ oxidoreductase
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| Reaction(IUBMB) |
(2S,3S)-butane-2,3-diol + NAD+ = (S)-acetoin + NADH + H+ [RN: R03707]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
This enzyme catalyses the reversible reduction of (S)-acetoin to (S,S)-butane-2,3-diol. It can also catalyse the irreversible reduction of diacetyl to (S)-acetoin.
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| History |
EC 1.1.1.76 created 1972, modified 2010
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| Pathway |
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| Orthology |
| K03366 | meso-butanediol dehydrogenase / (S,S)-butanediol dehydrogenase / diacetyl reductase |
| K18009 | meso-butanediol dehydrogenase / (S,S)-butanediol dehydrogenase / diacetyl reductase |
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| Genes |
» show all
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| Reference |
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| Authors |
TAYLOR MB, JUNI E. |
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| Title |
Stereoisomeric specificities of 2,3-butanediol dehydrogenases. |
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| Journal |
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| Reference |
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| Authors |
Carballo J, Martin R, Bernardo A, Gonzalez J |
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| Title |
Purification, characterization and some properties of diacetyl(acetoin) reductase from Enterobacter aerogenes. |
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| Journal |
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| Reference |
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| Authors |
Takusagawa Y, Otagiri M, Ui S, Ohtsuki T, Mimura A, Ohkuma M, Kudo T |
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| Title |
Purification and characterization of L-2,3-butanediol dehydrogenase of Brevibacterium saccharolyticum C-1012 expressed in Escherichia coli. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 1.1.1.76 |
| ExPASy - ENZYME nomenclature database: | 1.1.1.76 |
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| LinkDB |
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