KEGG   ENZYME: 1.1.1.77
Entry
EC 1.1.1.77                 Enzyme                                 
Name
lactaldehyde reductase;
propanediol:nicotinamide adenine dinucleotide (NAD) oxidoreductase;
L-lactaldehyde:propanediol oxidoreductase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
(R)[or (S)]-propane-1,2-diol:NAD+ oxidoreductase
Reaction(IUBMB)
(R)[or (S)]-propane-1,2-diol + NAD+ = (R)[or (S)]-lactaldehyde + NADH + H+ [RN:R02258 R03080]
Reaction(KEGG)
R02258 R03080;
(other) R01781 R02257
Substrate
(R)-propane-1,2-diol [CPD:C02912];
(S)-propane-1,2-diol [CPD:C02917];
NAD+ [CPD:C00003]
Product
(R)-lactaldehyde [CPD:C00937];
(S)-lactaldehyde [CPD:C00424];
NADH [CPD:C00004];
H+ [CPD:C00080]
History
EC 1.1.1.77 created 1972
Pathway
ec00630  Glyoxylate and dicarboxylate metabolism
ec00640  Propanoate metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K00048  lactaldehyde reductase
Genes
ECOb2799(fucO)
ECJJW2770(fucO)
ECDECDH10B_2968(fucO)
EBWBWG_2537(fucO)
ECOKECMDS42_2304(fucO)
ECOCC3026_15390
ECEZ4116(fucO)
ECSECs_3659(fucO)
ECFECH74115_4063(fucO)
ETWECSP_3751(fucO)
ELXCDCO157_3414
EOIECO111_3524(fucO)
EOJECO26_3869(fucO)
EOHECO103_3342(fucO)
ECOOECRM13514_3662(fucO)
ECOHECRM13516_3526(fucO)
ESLO3K_05500
ESOO3O_20150
ESMO3M_05545
ECKEC55989_3078(fucO)
ECGE2348C_3066(fucO)
EOKG2583_3452(fucO)
ELRECO55CA74_16460
ELHETEC_2989
ECWEcE24377A_3104(fucO)
EUNUMNK88_3484(fucO)
ECPECP_2782
ENAECNA114_2838(fucO)
ECOSEC958_3069(fucO)
ECVAPECO1_3732(fucO)
ECOAAPECO78_17615
ECXEcHS_A2943(fucO)
ECMEcSMS35_2939(fucO)
ECYECSE_3059
ECRECIAI1_2909(fucO)
ECQECED1_3252(fucO)
EUMECUMN_3128(fucO)
ECTECIAI39_3221(fucO)
EOCCE10_3225(fucO)
EBRECB_02644(fucO)
ECOBC3029_17935
EBLECD_02644(fucO)
EBEB21_02606(fucO)
EBDECBD_0929
ECIUTI89_C3170(fucO)
EIHECOK1_3175(fucO)
ECZECS88_3068(fucO)
ECCc3367(fucO)
ELOEC042_2997(fucO)
ELNNRG857_13710
ESEECSF_2590
ECLEcolC_0913
EKOEKO11_0969
EKFKO11_08960(fucO)
EABECABU_c30690(fucO)
EDHEcDH1_0889
EDJECDH1ME8569_2709(fucO)
ELUUM146_02570
ELWECW_m3009(fucO)
ELLWFL_14700(fucO)
ELCi14_3091(fucO)
ELDi02_3091(fucO)
ELPP12B_c2897(fucO)
ELFLF82_0772(fucO)
ECOLLY180_14225
ECOIECOPMV1_03056(fucO)
ECOJP423_15305
EALEAKF1_ch3215(fucO)
EMAC1192_21675
ESZFEM44_03875(fucO)
STYSTY3112(fucO)
STTt2881(fucO)
SEXSTBHUCCB_30380
SENTTY21A_14575
STMSTM2973(fucO)
SEOSTM14_3586(fucO)
SEVSTMMW_29361
SEYSL1344_2953(fucO)
SEMSTMDT12_C30250
SEJSTMUK_2961(fucO)
SEBSTM474_3118(fucO)
SEFUMN798_3231(fucO)
SETUSTU288_15040
SETCCFSAN001921_02205
SENRSTMDT2_28741(fucO)
SENDDT104_29711(fucO)
SENICY43_15510
SEENSE451236_20960
SPTSPA2837(fucO)
SEKSSPA2643
SPQSPAB_03699
SEISPC_3030(fucO)
SECSCH_2912(fucO)
SEHSeHA_C3181(fucO)
SHBSU5_03462
SENHCFSAN002069_17355
SEEHSEEH1578_00920
SEESNSL254_A3196(fucO)
SENNSN31241_40830
SEWSeSA_A3133(fucO)
SEASeAg_B3116(fucO)
SENSQ786_14370
SEDSeD_A3296(fucO)
SEGSG2883(fucO)
SELSPUL_2982(fucO)
SEGASPUCDC_2968(fucO)
SETSEN2818(fucO)
SENAAU38_14305
SENOAU37_14315
SENVAU39_14315
SENQAU40_16110
SENLIY59_14910
SENJCFSAN001992_18700
SEECCFSAN002050_21220
SEEBSEEB0189_005260
SEEPI137_14175
SENBBN855_30340(fucO)
SENEIA1_14305
SENCSEET0819_21730
SESSARI_04689
SALZEOS98_04565
SFLSF2813(fucO)
SFXS3008(fucO)
SFVSFV_2878(fucO)
SFESFxv_3085(fucO)
SFNSFy_4001
SFSSFyv_4080
SFTNCTC1_03093(fucO)
SSNSSON_2956(fucO)
SDYSDY_3016(fucO)
SDZAsd1617_04044
SHQA0259_17570
ELGBH714_10025
KPNKPN_03150(fucO)
KPUKP1_4430(fucO)
KPMKPHS_42300
KPPA79E_0944
KPHKPNIH24_07655
KPZKPNIH27_20475
KPVKPNIH29_21240
KPWKPNIH30_21260
KPGKPNIH32_22120
KPCKPNIH10_21055
KPQKPR0928_20540
KPTVK055_4361(fucO)
KPOKPN2242_18785
KPRKPR_4164(fucO)
KPJN559_1077
KPID364_16065
KPAKPNJ1_01082
KPSKPNJ2_01113
KPXPMK1_00633(fucO)
KPBFH42_11780
KPNEKU54_005310
KPNULI86_05320
KPNKBN49_0962(fucO)
KVAKvar_0903
KPEKPK_0969(fucO)
KPKA593_05950
KVDKR75_03400
KVQSP68_09945
KOXKOX_00865
KOEA225_4622
KOYJ415_08835
KOMHR38_26965
KOKKONIH1_23190
KOCAB185_13075
KQUAVR78_25565
KQVB8P98_05320
KLLBJF97_23060
KLWDA718_06130(fucO)
KARLGL98_04815(fucO)
KGRJJJ10_06110(fucO)
KPASLUW96_00950(fucO)
KLCK7H21_05790(fucO)
KLMBWI76_22480
RORRORB6_23530
RONTE10_22715
RPLNB1209_04885
RAODSD31_05015
CKOCKO_04157
CFDCFNIH1_00935
CBRAA6J81_22075
CWECO701_03400
CYOCD187_04865 CD187_10465
CPOTFOB25_16195(fucO)
CFQC2U38_20205
CAMAF384_04810
CIFAL515_18580
CFARCI104_09905
CIEAN232_09425
CPARCUC49_14420
CTELGBC03_20365(fucO)
CITZE4Z61_21495(fucO)
CARSE1B03_21290(fucO)
CIXM4I31_04700(fucO)
CIBHF677_004605(fucO)
CENSP2W74_04550(fucO)
CNTJT31_11925
ESCEntcl_3258
KLEAO703_05960
KIENCTC12125_04902(fucO)
KCYRIN60_04650(fucO)
SYMK6K13_03510(fucO)
ASUBNLZ15_04830(fucO) NLZ15_06145(fucO)
EBUCUC76_20490
EBBF652_2135 F652_3782
YEFFORC2_3258
YEEYE5303_24951(fucO)
YALAT01_3339(fucO)
YINCH53_840(fucO)
YAKACZ76_13245
YMADA391_17705
YCAF0T03_04815(fucO)
YASN0H69_04540(fucO)
YKIHRD70_09085(fucO)
SFWWN53_24680
GQUAWC35_09855
PRODPCO85_03645(fucO)
SERASer39006_021805
SERQCWC46_21815
ECAECA0742(fucO)
PATREV46_03230
PATOGZ59_06490(fucO)
PCTPC1_0621
PCCPCC21_006520
PWAPecwa_0837
PPARA8F97_14755
PECW5S_0743
PWSA7983_11690
PPOABJK05_20150
PBRAB5S52_18455
PPUJE2566_03635(fucO)
PARII2D83_18545(fucO)
PAQUDMB82_0003790(fucO)
PPAVLOZ86_04045(fucO)
PQUIG609_003225(fucO)
PCACOI450_03510(fucO)
PACBM9782_05705(fucO)
DDDDda3937_02309(fucO)
DZEDd1591_3438
DDCDd586_0626
DSOA4U42_12470
CEDLH89_08965
DFNCVE23_03770
DAQDAQ1742_00734(fucO)
DDADd703_3316
BNGEH206_14695
SODSant_3781(fucO)
SLIGGTU79_26625(fucO)
EBIEbC_38970(fucO)
ETPLU633_03390(fucO)
PVAPvag_pPag30186(fucO)
PAGGAL522_02455
PAGCBEE12_19750
PANSFCN45_08325(fucO)
PEYEE896_20520(fucO)
PJIKTJ90_20840(fucO)
PANOOJ965_01850(fucO)
KPIEN5580_20395(fucO)
PALFK6R05_21380(fucO)
PHEINCTC12003_02670(fucO)
PHAGPZ638_18550(fucO)
ETRETAE_0294(fucO)
ETDETAF_0255
ETEETEE_2050(fucO)
ETCETAC_01260
EDWQY76_01425
EDLAAZ33_01320(fucO)
EHOA9798_15165
HAVAT03_02820
HPARAL518_02710
OPODSM2777_00195
LPVHYN51_02740
LRINCTC12151_01551(fucO)
HPAAE5Q53_06060(fucO)
GLECJD39_08805
PDAG4362423_01526(adhE_1)
PATLKGI96_09210(fucO)
MSUMS2325(eutG)
BSUNA4G13_08725
MHTD648_860
MHQD650_27270
MHATB824_780
MHXMHH_c06200(fucO)
MHAEF382_07710
MHAMJ450_07320
MHAOJ451_08260
MHALN220_00360
MHAQWC39_13695
MHAYVK67_13700
MVRX781_290
MVIX808_20800
MVGX874_19530
MVEX875_450
MGRAA4G16_10495
MBOSICJ55_02120(fucO)
MANNGM695_02385(fucO)
APLAPL_1689
APJAPJL_1721(fucO)
APAAPP7_1750
APORDDU33_03475
AIOEXH44_05485(fucO)
ALIGNCTC10568_02060(fucO)
AGPNYR63_09120(fucO)
AGKNYR60_07750(fucO)
AAZADJ80_04660
BHUDA6A11_00765
PAETNCTC13378_02025(adhE_2)
GAPGAPWK_0810
GAQRAM11_02395(fucO) RAM11_09055(fucO)
ORBIPMB12_09985(fucO)
MEYTM49_03330
TAPGZ22_04230
LWIUE46_15950
LGZNCTC10812_00426(fucO)
LNWOTR81_05570(fucO)
PMAELMZ02_01670(fucO)
LANIFAX13_09485(fucO)
EFCEFAU004_00251(fucO)
EFAUEFAU085_00209(fucO)
EFUHMPREF0351_10216(fucO)
EFMM7W_438
EFTM395_01185
ECASECBG_00211
EMUEMQU_0360(fucO)
EGAAL523_00120
EGVEGCR1_10540 EGCR1_10545
EAVEH197_03275 EH197_05400 EH197_21870
ELACI4Q40_01200(fucO)
ERAFJ9537_12675(fucO)
EIEENLAB_08440(dhaT_1)
MPSMPTP_0452
MPXMPD5_1453
VCPH9L18_11300(fucO)
AURHMPREF9243_0028(fucO)
AUNAWM73_08955
ALOYCJ190_000145(fucO)
AMITDBT49_0000180(fucO)
ATJDBT50_000170(fucO)
CRNCAR_c23580(fucO)
MARRBKP56_10900
JEHEJN90_12235
CPFCPF_1046(fucO)
CPRCPR_0927(fucO)
CBECbei_0455
CBZCbs_0455
CBEILF65_00522
CCBClocel_1504
CSRCspa_c38150(fucO)
CBVU729_293(fucO)
CCKCcar_19145 Ccar_19365
CEUA7L45_04860
CLOSDMR38_14110(fucO)
CMAHC1I91_22770 C1I91_22790
CRWCROST_031400(fucO)
CFBCLFE_031300(fucO)
CAUNCLAUR_044890(fucO)
CNNCNEO_0902(fucO)
HHJNQ487_13085(fucO)
FSAC5Q98_00095
ESRES1_21710
ESUEUS_08500
RUSRBI_I00872(lactal_redase)
RUJE5Z56_00945(fucO)
FPRFP2_03020
FPAFPR_25610
FPRACG447_04420
FDUGXM22_04510(fucO)
CAMLH6X83_10185(fucO)
SMANC12CBH8_04650(fucO)
SVJNQ490_00080(fucO)
AIMPYS61_04110(fucO)
ANQPYS63_02705(fucO)
AMURADH66_17565
ELMELI_1743
EMTCPZ25_001920
ELIMB2M23_15995
EVNNQ558_05005(fucO)
BPENNQ488_06840(fucO)
BPRSCK3_09620
BPBbpr_I2065(fucO)
BFICIY_11260
RHORHOM_02690
RIXRO1_27530
RIMROI_38980
RRKH8S51_006635(fucO)
COOCCU_18150
CCOMI6K69_04770(fucO)
CEVLK421_07425(fucO)
ROBCK5_32750
BLIQINP51_13555(fucO)
BWXNQ550_00850(fucO)
LACYA4V08_08905
LXAOW255_09285(fucO)
BPRLCL2_05000
ARFAR1Y2_0175
ACACEYQ97_16675(fucO)
LUAD4A81_01720
LGGQJR73_00800(fucO)
EHLEHLA_2227
PXVFXF36_14020(fucO)
EELEUBELI_20348
RTORTO_07870
RGNRGna_03420
RLRNQ541_02515(fucO)
CBOLCGC65_21450
CASPNQ535_08460(fucO)
DLOK5I24_15025(fucO)
DFMNQ560_06395(fucO)
WCPH9Q76_09970(fucO)
SSUNH9Q77_05805(fucO)
WHJH9Q79_14950
AHBbsdtb5_04310
EREEUBREC_1091
ERTEUR_21180
ERAERE_20340
LBXlbkm_0165 lbkm_1419
ABUTAmi103574_11585(fucO)
PSORRSJ16_09015
ROCHF520_02765(fucO)
RILCRIB_1300
PHXKGNDJEFE_02248(fucO)
CMIUB1H56_07465
VPRVpar_1772
VATB7L28_09105
VRM44547418_01870(fucO)
VDNNCTC11831_01936(fucO)
VNKVEIT17_18420(fucO)
VRGOKW85_09680(fucO)
MHWACT01_02555
MMAXLCQ47_02315(fucO)
MHGMHY_22270
MFUNGXM21_01235(fucO)
PUFUFO1_0900
ERLAOC36_11120
AARGAargi30884_18520(fucO)
ABSIA9CBEGH2_16580(fucO)
EBMSG0102_11690(fucO)
AMUOKWG62_04430(fucO)
AHQNMU03_12520(fucO)
TSGHLK68_02275(fucO)
FITFi14EGH31_05910(fucO)
ERMEYR00_05250(fucO)
TSFNQ543_02715(fucO)
CMITNQ499_09555(fucO)
MCDMCRO_0019(fucO)
OLSOlsu_1397
PCATPcatena_12500(dhaT_1)
TIOINP52_06915(fucO)
LCALATTO_12940
CGOCorgl_1645
CAERCSV91_04495
CSTCLK434_07960(fucO)
XYLET495_16740
CFICelf_0682 Celf_2989
PAUSNCTC13651_02019(fucO)
TEJKDB89_01815(fucO)
AWLP8A24_00405(fucO)
ACASP7079_00250(fucO)
ASGFB03_05435
AUUCJ184_002170(fucO)
ATIMCYJ17_0000945(fucO)
ACTTDDD63_00615
ANEATCC27039_12580(fucO)
AVCNCTC10951_01106(fucO)
AWEJG540_06715(fucO)
AMASQU670_05505(fucO)
ALILD5R93_04970
BLOBL1673(fucO)
BLJBLD_1839(dhaT)
BLNBlon_0540
BLONBLIJ_0544
BLFBLIF_1657
BLLBLJ_1640
BLBBBMN68_1706(dhaT)
BLMBLLJ_1588
BLKBLNIAS_00456(dhaT)
BLGBIL_03160
BLZBLGT_08485
BLXGS08_08515
BADBAD_0403(fucO)
BADLBADO_0408
BADOBBMN23_0434
BDEBDP_0538(fucO)
BDNBBDE_0514
BBPBBPR_1454(fucO)
BBIBBIF_1397(fucO)
BBFBBB_1430(fucO)
BBVHMPREF9228_1556(fucO)
BBRUBbr_1505(fucO)
BBREB12L_1429
BBRVB689b_1540
BBRJB7017_1701
BBRCB7019_1701
BBRNB2258_1485
BBRSBS27_1529(fucO)
BBRDBBBR_1543
BTPD805_1345
BKAAH68_02275
BKSBBKW_0435
BCATBBCT_0383
BPSPAH67_02640
BANGBBAG_1271
BPSCBBPC_0429
BSCABBSC_0612
BCHOBcFMB_02410
BGXESN35_08450
BLEMBL8807_06855(fucO)
BEUBE0216_04755(fucO) BE0216_05730(fucO)
BFJB19861_03880(fucO)
GVGHMPREF0421_20697(fucO)
GVHHMPREF9231_0868(fucO)
GPTK9E43_05765(fucO)
PDOPSDT_0461
ABAOBEQ56_06400
TSUTresu_0976
TBETrebr_0125
TRCDYE49_08025
OCKEXM22_13645(fucO)
BRMBmur_2495
BPOBP951000_0138(adh)
BPJB2904_orf1430
BPIPBPP43_02400
BPWWESB_1300
BIPBint_1818
FPDCTM68_03905
FMOC4N19_01255 C4N19_03870
FPOLERS445057_02153(fucO)
LBALebu_1790
LOTAXF11_04760
LEQBCB68_02615
LHFJCM16775_0670
LSZJCM16776_1129
LHGJMUB5056_1781
LTEJMUB4039_0597
CPORBED41_08915
BTHBT_3767
BTHOBtheta7330_04521(fucO)
BFRBF0254
BFSBF9343_0210(fucO)
BFGBF638R_0266(fucO)
BFBVU15_00610
BHLBache_2994
BXYBXY_48200
BOABovatus_03889(fucO)
BCELBcellWH2_00070(fucO)
BCACCGC64_05735(fucO)
BISDXK01_016820(fucO)
BUNBun01g_02930
BEGINE88_01383(fucO)
BSTEK6V31_12280(fucO)
BFEK6V30_07325(fucO)
BNOK8P02_21020(fucO)
BFCBacF7301_07520(fucO)
BSALK6V25_05175(fucO)
BFINBFINE_02410
BVUBVU_1251
BSABacsa_2637
BDOEL88_00840
BDHGV66_05295
PCOPI6J50_11145(fucO)
MICAP0L94_07575(fucO)
PGOLK6V26_03015(fucO)
PFAINXY11_01985(fucO)
DDBE7747_00775(fucO)
PIINF347_09035(fucO)
BVSBARVI_11200
COPRCop2CBH44_14940
PBYL6471_11970(fucO)
SHOIKUA50_006175(fucO)
SBAOL6469_06855(fucO)
ALDGFH31_04160(fucO)
AOKA3BBH6_11560
ACOUA5CBH24_07160
AITAI2BBH_18140
ASENNQ519_01435(fucO)
AIUNQ491_02775(fucO)
FGLEM308_07645 EM308_11970
 » show all
Reference
1  [PMID:14203169]
  Authors
TING SM, SELLINGER OZ, MILLER ON
  Title
THE METABOLISM OF LACTALDEHYDE. VI. THE REDUCTION OF D- AND L-LACTALDEHYDE IN RAT LIVER.
  Journal
Biochim Biophys Acta 89:217-25 (1964)
DOI:10.1016/0926-6569(64)90210-x
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.77
IUBMB Enzyme Nomenclature: 1.1.1.77
ExPASy - ENZYME nomenclature database: 1.1.1.77
BRENDA, the Enzyme Database: 1.1.1.77
CAS: 37250-15-0
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