KEGG ENZYME: 1.14.13.29

ENZYME: 1.14.13.29

Entry

EC 1.14.13.29               Enzyme

Name

4-nitrophenol 2-monooxygenase;
4-nitrophenol hydroxylase;
4-nitrophenol-2-hydroxylase

Class

Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor

Sysname

4-nitrophenol,NADH:oxygen oxidoreductase (2-hydroxylating)

Reaction(IUBMB)

4-nitrophenol + NADH + H+ + O2 = 4-nitrocatechol + NAD+ + H2O [RN:R03023]

Reaction(KEGG)

R03023

Substrate

4-nitrophenol [CPD:C00870];
NADH [CPD:C00004];
H+ [CPD:C00080];
O2 [CPD:C00007]

Product

4-nitrocatechol [CPD:C02235];
NAD+ [CPD:C00003];
H2O [CPD:C00001]

Comment

A flavoprotein (FAD).

History

EC 1.14.13.29 created 1989

Pathway

ec00627

Aminobenzoate degradation

ec01120

Microbial metabolism in diverse environments

Orthology

K21726

4-nitrophenol 2-monooxygenase / 4-nitrocatechol 4-monooxygenase, oxygenase component

Genes

RHR:	CKA34_21595

BBRA:

QA636_08105

SPHO:

C3E99_15575

SDX:	C4B68_24960

ARY:	ATC04_18335

ACH:

Achl_4573

BALA:

DSM104299_02060(npcA)

SBAE:

DSM104329_03552(npcA_2)

Reference

1 [PMID:6477623]

Authors

Mitra D, Vaidyanathan CS.

Title

A new 4-nitrophenol 2-hydroxylase from a Nocardia sp.

Journal

Biochem Int 8:609-15 (1984)

Other DBs

ExplorEnz - The Enzyme Database:

1.14.13.29

IUBMB Enzyme Nomenclature:

1.14.13.29

ExPASy - ENZYME nomenclature database:

1.14.13.29

UM-BBD (Biocatalysis/Biodegradation Database):

1.14.13.29

BRENDA, the Enzyme Database:

1.14.13.29

CAS:	91116-87-9

LinkDB

DBGET integrated database retrieval system