KEGG   ENZYME: 1.14.19.76
Entry
EC 1.14.19.76               Enzyme                                 
Name
flavone synthase II;
CYP93B16 (gene name);
CYP93G1 (gene name);
FNS II
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
Sysname
flavanone,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (flavone-forming)
Reaction(IUBMB)
a flavanone + [reduced NADPH---hemoprotein reductase] + O2 = a flavone + [oxidized NADPH---hemoprotein reductase] + 2 H2O [RN:R12276]
Reaction(KEGG)
R12276 > R12277 R12278 R12279
Substrate
flavanone [CPD:C00766];
[reduced NADPH---hemoprotein reductase] [CPD:C03024];
O2 [CPD:C00007]
Product
flavone [CPD:C15608];
[oxidized NADPH---hemoprotein reductase] [CPD:C03161];
H2O [CPD:C00001]
Comment
A cytochrome P-450 (heme-thiolate) protein found in plants. The rice enzyme channels flavanones to the biosynthesis of tricin O-linked conjugates. cf. EC 1.14.20.5, flavone synthase I.
History
EC 1.14.19.76 created 2018
Pathway
ec00941  Flavonoid biosynthesis
ec00943  Isoflavonoid biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K23179  flavone synthase II
K23180  flavone synthase II
Genes
CIT: 102607946 102609972 102611200
CIC: CICLE_v10019810mg CICLE_v10019811mg
PVY: 116113484 116113521 116129556 116145436
MINC: 123203073
TCC: 18593008 18593084
GRA: 105781200
GHI: 107895096 107919519
GAB: 108463531
HSYR: 120113983 120124673
DZI: 111284583 111315053
EGR: 104432774 104432776
RARG: 115752204
GMX: 100783503(FNSII-1) 100784036(FNSII-2)
GSJ: 114379343
PVU: 137819152
VAR: 108323455
VUN: 114169631
CCAJ: 109798920
APRC: 113857422 113859174
MTR: 25485387 25492470 25492471
TPRA: 123918495
CAM: 101511254
PSAT: 127105441
VVO: 131601961 131607001 131656934
ADU: 107477091
AIP: 107634112
AHF: 112736589 112768987
LANG: 109351612 109351614
PCIN: 129295228 129313542
RCU: 8286099 8286101
MEAN: 126654554
HBR: 110637536 110639710 110670394
MESC: 110613186 110625897
POP: 18098816 7473876
PEU: 105124985
PALZ: 118053247
PNZ: 133669480 133669482 133669583
AGLU: 133878474
LBB: 132626350
SIND: 105170377
OEU: 111402974
EGT: 105949064 105949083
SSPL: 121740953 121743927
SMIL: 131000745
SHIS: 125191117
APAN: 127253820 127253839
HAN: 110873193
ECAD: 122587139
LSV: 111905568
CCAV: 112518085
CSIN: 114286595 114296673 114307649 114322163
RVL: 131314795
MOF: 131149350
OSA: 4334886
DOSA: Os04g0101400
OBR: 102714554 102716963
OGL: 127770153
BDI: 100841298
ATS: 109733276
TDC: 119352891 119361919
TAES: 123043285 123051157 123187112
TUA: 125535225
LPER: 127331054
LRD: 124677445
SBI: 8056944
ZMA: 103641445 103642652 103646891
MFLO: 136492961
SITA: 101761949
SVS: 117862541
PVIR: 120639519 120639522 120681960
PHAI: 112900040
PAUA: 133887963
 » show all
Reference
1  [PMID:10652133]
  Authors
Martens S, Forkmann G
  Title
Cloning and expression of flavone synthase II from Gerbera hybrids.
  Journal
Plant J 20:611-8 (1999)
DOI:10.1046/j.1365-313X.1999.00636.x
  Sequence
[ag:AAD39549]
Reference
2  [PMID:20132953]
  Authors
Fliegmann J, Furtwangler K, Malterer G, Cantarello C, Schuler G, Ebel J, Mithofer A
  Title
Flavone synthase II (CYP93B16) from soybean (Glycine max L.).
  Journal
Phytochemistry 71:508-14 (2010)
DOI:10.1016/j.phytochem.2010.01.007
  Sequence
[gmx:100783503]
Reference
3  [PMID:24843076]
  Authors
Lam PY, Zhu FY, Chan WL, Liu H, Lo C
  Title
Cytochrome P450 93G1 Is a Flavone Synthase II That Channels Flavanones to the Biosynthesis of Tricin O-Linked Conjugates in Rice.
  Journal
Plant Physiol 165:1315-1327 (2014)
DOI:10.1104/pp.114.239723
  Sequence
[osa:4334886]
Other DBs
ExplorEnz - The Enzyme Database: 1.14.19.76
IUBMB Enzyme Nomenclature: 1.14.19.76
ExPASy - ENZYME nomenclature database: 1.14.19.76
BRENDA, the Enzyme Database: 1.14.19.76
LinkDB

DBGET integrated database retrieval system