Entry
Name
pyruvate oxidase (CoA-acetylating)
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With oxygen as acceptor
BRITE hierarchy
Sysname
pyruvate:oxygen 2-oxidoreductase (CoA-acetylating)
Reaction(IUBMB)
pyruvate + CoA + O2 = acetyl-CoA + CO2 + H2O2 [RN:
R00211 ]
Reaction(KEGG)
Substrate
Product
Comment
A flavoprotein (FAD). May be identical with EC
1.2.7.1 pyruvate synthase.
History
EC 1.2.3.6 created 1976
Pathway
Reference
Authors
Reeves RE, Warren LG, Susskind B, Lo HS.
Title
An energy-conserving pyruvate-to-acetate pathway in Entamoeba histolytica. Pyruvate synthase and a new acetate thiokinase.
Journal
J Biol Chem 252:726-31 (1977)
Reference
Authors
Takeuchi T, Weinbach EC, Diamond LS.
Title
Pyruvate oxidase (CoA acetylating) in Entamoeba histolytica.
Journal
Other DBs
ExplorEnz - The Enzyme Database: 1.2.3.6
ExPASy - ENZYME nomenclature database: 1.2.3.6
BRENDA, the Enzyme Database: 1.2.3.6
LinkDB
All DBs