KEGG ENZYME: 1.3.1.19

ENZYME: 1.3.1.19

Entry

EC 1.3.1.19                 Enzyme

Name

cis-1,2-dihydrobenzene-1,2-diol dehydrogenase;
cis-benzene glycol dehydrogenase;
cis-1,2-dihydrocyclohexa-3,5-diene (nicotinamide adenine dinucleotide) oxidoreductase

Class

Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor

Sysname

cis-1,2-dihydrobenzene-1,2-diol:NAD+ oxidoreductase

Reaction(IUBMB)

cis-1,2-dihydrobenzene-1,2-diol + NAD+ = catechol + NADH + H+ [RN:R00812]

Reaction(KEGG)

R00812;
(other) R04088 R05354 R07703

Substrate

cis-1,2-dihydrobenzene-1,2-diol [CPD:C04091];
NAD+ [CPD:C00003]

Product

catechol [CPD:C00090];
NADH [CPD:C00004];
H+ [CPD:C00080]

History

EC 1.3.1.19 created 1972

Pathway

ec00361

Chlorocyclohexane and chlorobenzene degradation

ec00362

Benzoate degradation

ec00623

Toluene degradation

ec00624

Polycyclic aromatic hydrocarbon degradation

ec00643

Styrene degradation

ec01100

Metabolic pathways

ec01120

Microbial metabolism in diverse environments

Orthology

K16269

cis-1,2-dihydrobenzene-1,2-diol/chlorobenzene dihydrodiol dehydrogenase

Genes

PPF:

Pput_2877

PPX:	T1E_4270(tobD)

PMON:

X969_10950

PMOT:

X970_10605

PASI:

LG197_17470(bphB)

BPT:	Bpet3742(hcaB)

ATEM:

PQV96_18690(bphB)

Reference

1 [PMID:4362337]

Authors

Axcell BC, Geary PJ.

Title

The metabolism of benzene by bacteria. Purification and some properties of the enzyme cis-1,2-dihydroxycyclohexa-3,5-diene (nicotinamide adenine dinucleotide) oxidoreductase (cis-benzene glycol dehydrogenase).

Journal

Biochem J 136:927-34 (1973)
DOI:10.1042/bj1360927

Reference

2 [PMID:4298226]

Authors

Gibson DT, Koch JR, Kallio RE.

Title

Oxidative degradation of aromatic hydrocarbons by microorganisms. I. Enzymatic formation of catechol from benzene.

Journal

Biochemistry 7:2653-62 (1968)
DOI:10.1021/bi00847a031

Other DBs

ExplorEnz - The Enzyme Database: