KEGG   ENZYME: 1.4.1.11
Entry
EC 1.4.1.11                 Enzyme                                 
Name
L-erythro-3,5-diaminohexanoate dehydrogenase;
L-3,5-diaminohexanoate dehydrogenase
Class
Oxidoreductases;
Acting on the CH-NH2 group of donors;
With NAD+ or NADP+ as acceptor
Sysname
L-erythro-3,5-diaminohexanoate:NAD+ oxidoreductase (deaminating)
Reaction(IUBMB)
L-erythro-3,5-diaminohexanoate + H2O + NAD+ = (S)-5-amino-3-oxohexanoate + NH3 + NADH + H+ [RN:R03349]
Reaction(KEGG)
R03349
Substrate
L-erythro-3,5-diaminohexanoate [CPD:C01186];
H2O [CPD:C00001];
NAD+ [CPD:C00003]
Product
(S)-5-amino-3-oxohexanoate [CPD:C03656];
NH3 [CPD:C00014];
NADH [CPD:C00004];
H+ [CPD:C00080]
History
EC 1.4.1.11 created 1976
Pathway
ec00310  Lysine degradation
ec01100  Metabolic pathways
Orthology
K18012  L-erythro-3,5-diaminohexanoate dehydrogenase
Genes
RFR: Rfer_3890
NOK: FAY22_04170
ARES: IWH25_08660
APET: ToN1_41350
AZA: AZKH_1574(yhdH)
AZI: AzCIB_1066
NOH: G5V57_09660
DEK: DSLASN_49450(kdd)
ADE: Adeh_3294
ACP: A2cp1_3414
AFW: Anae109_3348
ANK: AnaeK_3370
AORY: AMOR_39750(kdd)
APAU: AMPC_17840(kdd)
MXA: MXAN_4391
MSD: MYSTI_04880
MYM: A176_002511
MFB: MFUL124B02_26705
CCX: COCOR_03521
MFU: LILAB_30045
MMAS: MYMAC_004305
SUR: STAUR_4751
AGE: AA314_04545
AVM: JQX13_36705
MBD: MEBOL_007836
VIN: AKJ08_2044
SCL: sce2462
SCU: SCE1572_14815
CCRO: CMC5_039320
PAUU: E8A73_026785
MRM: A7982_05652
LLU: AKJ09_02720
BSED: DN745_01640
PCAY: FRD00_14910
BBAE: FRD01_13890
AFX: JZ786_00845
ACUR: JZ785_19345
ACYC: JI721_05895
TUM: CBW65_05635
TAB: CIG75_01535
LFB: C1X05_16420
TVU: AB849_005115
KPUL: GXN76_15770
KEB: GXN75_17105
PABS: JIR001_31260(kdd)
CLS: CXIVA_06650
CPAT: CLPA_c31490(kdd)
CPAE: CPAST_c31490(kdd)
CEU: A7L45_04290
CARG: RSJ17_19910
CCAA: KQH81_17165
CRW: CROST_000180(kdd)
CFB: CLFE_002820(kdd)
CAUN: CLAUR_029770(kdd)
CTAG: LL095_01360
AMT: Amet_4553
AOE: Clos_0417
GFE: Gferi_11535
CRS: FQB35_13855
CPRF: K7H06_00025
CRAS: KVH43_03375
OCW: OW730_07270
FPLA: A4U99_02925 A4U99_11320
VFA: MM35RIKEN_07350(kdd)
VCOP: MM50RIKEN_12220(kdd)
LUA: D4A81_03620
CST: CLOST_1383(kdd)
TEB: T8CH_2403(kdd)
STH: STH34
DAI: Desaci_1869
FWA: DCMF_21025
AACX: DEACI_2072
VGU: HYG85_18530
VPY: HZI73_18000
ACAE: HYG86_10295
IBU: IB211_00979
AMIJ: EQM06_11660 EQM06_11665
AMIC: Ami3637_09130 Ami3637_09135
ABUT: Ami103574_15010 Ami103574_15015
ETM: CE91St48_07370(kdd_1) CE91St48_07380(kdd_2)
EUU: ADJ67_02630
TTE: TTE0722
TWI: Thewi_0851
NTH: Nther_1883 Nther_1902
HPK: Hprae_1564
HALS: D7D81_18040
IFN: GM661_14605
AFT: BBF96_12085 BBF96_13605
KME: H0A61_00953(kdd)
SPOA: EQM13_02785
KPAR: JL105_00825
SEDZ: JYG23_11300
PUF: UFO1_1637
PFT: JBW_02728
MANR: MPAN_016010(kdd)
MBJ: KQ51_00862(kdd)
XCL: G4Z02_00825
TBM: BK010_00740
TBZ: BK011_00640
TBK: HF295_06575
MPHL: MPHLCCUG_04685(kdd)
ICA: Intca_1790
ARS: ADJ73_12520
TEH: GKE56_04775
PHW: G7075_06415
PEI: H9L10_05995
ORN: DV701_02925
NCA: Noca_2662
NOY: EXE57_02155
NOI: FCL41_08525
NOO: FE634_10510
NDP: E2C04_09125
NSN: EXE58_17605
NANO: G5V58_11080
NMES: H9L09_20195
NPI: G7071_14785
NAQU: ENKNEFLB_02386(kdd)
NRO: K8W59_08680
NOQ: LN652_02040
NCQ: K6T13_09120
NPS: KRR39_08640
KFL: Kfla_3604
KQI: F1D05_03980
TCU: Tcur_2340
AGRA: AGRA3207_000449
BLAP: MVA48_03865
MMAR: MODMU_2629
SESP: BN6_43200
SSYI: EKG83_24045
KAL: KALB_4421
KPHY: AOZ06_28000
LED: BBK82_41130
ALO: CRK56462
ACTU: Actkin_03088(kdd)
STP: Strop_2263
SAQ: Sare_2382
MAU: Micau_3120
MIL: ML5_5275
MICB: MicB006_2174
MTUA: CSH63_09515
MICH: FJK98_17905
MTEM: GCE86_10820
MCAB: HXZ27_19865
MSAG: GCM10017556_54720(kdd)
VMA: VAB18032_20370
VER: HUT12_17870
MENO: Jiend_59910(kdd)
ASE: ACPL_2805
AMS: AMIS_47620
ACTN: L083_3924
AFS: AFR_21820
ACTS: ACWT_2741
AIH: Aiant_75440(kdd)
ACTR: Asp14428_06220(kdd)
PLK: CIK06_14130
PLAB: C6361_03345
PLAT: C6W10_18280
PFLA: Pflav_024740
PSUU: Psuf_079130(kdd)
ATL: Athai_29200(kdd)
ASER: Asera_45340(kdd)
PRY: Prubr_60550(kdd)
CATI: CS0771_51080(kdd)
DVC: Dvina_27785
DFU: Dfulv_24915
DROS: Drose_19980
DAUR: Daura_26265
DMAT: Dmats_23110
NHY: JQS43_13165
CCAZ: COUCH_20855
SNA: Snas_3952
NAV: JQS30_07335
GLY: K3N28_19465
FNU: FN1867
FNC: HMPREF0946_01615
FNT: HMPREF0405_01363
FUS: HMPREF0409_01395
FNE: FSDG_01974
FHW: RN87_00400
FPD: CTM68_06730
FVA: FV113G1_13770
FUL: C4N20_15460
FGO: C4N16_05140
FNF: BSQ88_03855
FPEI: C4N17_12365
FCI: I6I83_03010(kdd)
FHO: H9Q81_09950
CSOM: MKD34_03785
PGI: PG_1069
PGN: PGN_1165
PGT: PGTDC60_1139
PAH: Poras_0575
PCRE: NCTC12858_01515
PCAG: NCTC12856_01004
PEND: LA319_06745
PSOE: CE91St14_15590(kdd)
PET: PEIBARAKI_4150
OSP: Odosp_3172
BUY: D8S85_10220 D8S85_10225
BVIR: I6J59_05605 I6J59_05610
BACC: BRDCF_p1072 BRDCF_p1073
MBAS: ALGA_2256
CACI: CLOAM1348(kdd)
TLE: Tlet_1664
PHY: AJ81_05120
TME: Tmel_0191
TAF: THA_423
THP: BG95_02090
THER: Y592_02095
TFE: JYK00_06040
FNO: Fnod_0208
FPE: Ferpe_0540
FIA: NA23_03015
FRR: IB67_05770
OCY: OSSY52_05670(kdd)
PMO: Pmob_1079
MPZ: Marpi_0477
MARN: LN42_02760
OCS: OF820_10900
KOL: Kole_0964
KPF: IX53_04765
MPG: Theba_2112
MINF: MESINF_1635(kdd)
ASAC: ATHSA_1333
PSYT: DSAG12_00557
 » show all
Reference
1  [PMID:4344229]
  Authors
Baker JJ, Jeng I, Barker HA.
  Title
Purification and properties of L-erythro-3,5-diaminohexanoate dehydrogenase from a lysine-fermenting Clostridium.
  Journal
J Biol Chem 247:7724-34 (1972)
Other DBs
ExplorEnz - The Enzyme Database: 1.4.1.11
IUBMB Enzyme Nomenclature: 1.4.1.11
ExPASy - ENZYME nomenclature database: 1.4.1.11
BRENDA, the Enzyme Database: 1.4.1.11
CAS: 37377-90-5
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