Entry
Name
2-hydroxy-1,4-benzoquinone reductase;
hydroxybenzoquinone reductase;
1,2,4-trihydroxybenzene:NAD oxidoreductase
Class
Oxidoreductases;
Acting on NADH or NADPH;
With a quinone or similar compound as acceptor
BRITE hierarchy
Sysname
NADH:2-hydroxy-1,4-benzoquinone oxidoreductase
Reaction(IUBMB)
2-hydroxy-1,4-benzoquinone + NADH + H+ = hydroxyquinol + NAD+ [RN:
R05399 ]
Reaction(KEGG)
Substrate
Product
Comment
A flavoprotein (FMN) that differs in substrate specificity from other quinone reductases. The enzyme in Burkholderia cepacia is inducible by 2,4,5-trichlorophenoxyacetate.
History
EC 1.6.5.7 created 2000, modified 2004
Pathway
ec00361 Chlorocyclohexane and chlorobenzene degradation
ec01120 Microbial metabolism in diverse environments
Orthology
K23529 2-hydroxy-1,4-benzoquinone reductase
Genes
Taxonomy
Reference
Authors
Zaborina O, Daubaras DL, Zago A, Xun L, Saido K, Klem T, Nikolic D, Chakrabarty AM.
Title
Novel pathway for conversion of chlorohydroxyquinol to maleylacetate in Burkholderia cepacia AC1100.
Journal
Other DBs
ExplorEnz - The Enzyme Database: 1.6.5.7
ExPASy - ENZYME nomenclature database: 1.6.5.7
UM-BBD (Biocatalysis/Biodegradation Database): 1.6.5.7
BRENDA, the Enzyme Database: 1.6.5.7
LinkDB
All DBs