KEGG   ENZYME: 1.8.1.17
Entry
EC 1.8.1.17                 Enzyme                                 
Name
dimethylsulfone reductase
Class
Oxidoreductases;
Acting on a sulfur group of donors;
With NAD+ or NADP+ as acceptor
Reaction(IUBMB)
dimethyl sulfoxide + H2O + NAD+ = dimethyl sulfone + NADH + H+ [RN:R09498]
Reaction(KEGG)
R09498
Substrate
dimethyl sulfoxide [CPD:C11143];
H2O [CPD:C00001];
NAD+ [CPD:C00003]
Product
dimethyl sulfone [CPD:C11142];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
A molybdoprotein.
History
EC 1.8.1.17 created 2011
Pathway
ec00920  Sulfur metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Reference
1  [PMID:10896224]
  Authors
Borodina E, Kelly DP, Rainey FA, Ward-Rainey NL, Wood AP
  Title
Dimethylsulfone as a growth substrate for novel methylotrophic species of Hyphomicrobium and Arthrobacter.
  Journal
Arch Microbiol 173:425-37 (2000)
DOI:10.1007/s002030000165
Reference
2  [PMID:11807567]
  Authors
Borodina E, Kelly DP, Schumann P, Rainey FA, Ward-Rainey NL, Wood AP
  Title
Enzymes of dimethylsulfone metabolism and the phylogenetic characterization of the facultative methylotrophs Arthrobacter sulfonivorans sp. nov., Arthrobacter methylotrophus sp. nov., and Hyphomicrobium sulfonivorans sp. nov.
  Journal
Arch Microbiol 177:173-83 (2002)
DOI:10.1007/s00203-001-0373-3
Other DBs
ExplorEnz - The Enzyme Database: 1.8.1.17
IUBMB Enzyme Nomenclature: 1.8.1.17
ExPASy - ENZYME nomenclature database: 1.8.1.17
BRENDA, the Enzyme Database: 1.8.1.17
LinkDB

KEGG   REACTION: R09498
Entry
R09498                      Reaction                               
Name
dimethylsulfone reductase
Definition
Dimethyl sulfoxide + H2O + NAD+ <=> Dimethyl sulfone + NADH + H+
Equation
C11143 + C00001 + C00003 <=> C11142 + C00004 + C00080
Reaction class
RC00001  C00003_C00004
RC02554  C11142_C11143
Enzyme
1.8.1.17
Pathway
rn00920  Sulfur metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.8  Acting on a sulfur group of donors
   1.8.1  With NAD+ or NADP+ as acceptor
    1.8.1.17
     R09498  Dimethyl sulfoxide + H2O + NAD+ <=> Dimethyl sulfone + NADH + H+
Other DBs
RHEA: 30222
LinkDB

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