KEGG   ENZYME: 2.1.1.143
Entry
EC 2.1.1.143                Enzyme                                 
Name
24-methylenesterol C-methyltransferase;
SMT2;
24-methylenelophenol C-241-methyltransferase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
Sysname
S-adenosyl-L-methionine:24-methylenelophenol C-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + 24-methylenelophenol = S-adenosyl-L-homocysteine + (Z)-24-ethylidenelophenol [RN:R05776]
Reaction(KEGG)
R05776
Substrate
S-adenosyl-L-methionine [CPD:C00019];
24-methylenelophenol [CPD:C11522]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
(Z)-24-ethylidenelophenol [CPD:C11523]
Comment
This is the second methylation step of plant sterol biosynthesis (cf EC 2.1.1.142, cycloartenol 24-C-methyltransferase).
History
EC 2.1.1.143 created 2001
Pathway
ec00100  Steroid biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K08242  24-methylenesterol C-methyltransferase
Genes
AJM119042076
ATHAT1G20330(SMT2) AT1G76090(SMT3)
ALY9325120 9329159
CRB17894477 17897656
CSAT104702364 104713272 104740730 104751502 104751503 104756386 104776150
EUSEUTSA_v10008036mg EUTSA_v10018759mg
BRP103832055 108870355 117125925
BNA106347090 106347091 106349985 106406523 106421679 106432484 106433699 106433723
BOE106294968 106294969 106301097 106321642
RSZ108811804 108812221 108840045
THJ104809656 104811446 104813772
CPAP110818251
CIT102622046
CICCICLE_v10001625mg
PVY116123849
MINC123202644 123207086 123229864
TCC18591627
GRA105769621 105770011
GHI107904984 107905551 107937575 107959396
GAB108453816 108465469
DZI111301314 111312854 111315270
EGR104448882
GMX100791154(SMT2-2) 100804517(SMT2-1)
GSJ114408540 114414560
PVUPHAVU_009G020000g
VRA106759766 106764655
VAR108337167 108340969
VUN114164155 114193292
CCAJ109802073
APRC113848121 113864936
MTRMTR_3g114780
CAM101496973
LJALj1g3v2254700.1(Lj1g3v2254700.1) Lj1g3v2254710.1(Lj1g3v2254710.1) Lj1g3v2254710.2(Lj1g3v2254710.2) Lj1g3v2254710.3(Lj1g3v2254710.3)
ADU107460153
AIP107609799
AHF112705672 112763855
LANG109326439 109327939 109343982
FVE101296451
RCN112172637 112196080
PPER18788663
PMUM103321192
PAVI110768162
PDUL117630576
MDM103440234 103450343
PXB103927358
ZJU107422799 107427347 107427363
MNT21397452
CSV101220177
CMO103503852
BHJ120086466
MCHA111010418
CMAX111476770
CMOS111443718
CPEP111797180
RCU8267837
JCU105635287 105638506
HBR110632160 110659836 110661032
MESC110606716 110615919 110625967
POP7490620 7494000
PEU105109920 105132911
PALZ118052638 118061981
JRE108983486 109013948
QSU112004464
QLO115974557
TWL120000900 120009458 120010247
VVI100254003 100262458
VRI117907544 117909083
SLY101243835 101247376 101266635
SPEN107002277 107007757 107019203
SOT102583931 102589166 102596628
CANN107840596 107847066
NTA107764502 107765415 107800100 107821329
NSY104213055 104233478 104247475
NTO104085697 104104970
NAU109206588 109207000 109216124
INI109162135
ITR115996133
SIND105169815 105173015
OEU111381992 111381993 111412135
EGT105954649 105957794
SSPL121748932 121753152
HAN110911505 110922323
ECAD122578710 122581889 122587818
LSV111884276 111914976
CCAV112525279 112525875 112528178
DCR108226424 108226425 108226426
CSIN114260517 114313040
BVG104884507 104903798
SOE110776014
CQI110703617 110715078 110721664
NNU104603677
MING122082429 122083056
TSS122658011 122661951
PSOM113289029 113291543 113346753 113356950
NCOL116249168 116259802
OSA4331540
DOSAOs03t0136200-01(Os03g0136200)
OBR102714159
BDI100830846 100845021
ATS109735428 109766957
TDC119274583 119291928 119304033 119338335
TAES123051437 123093657 123098913 123105856 123127363 123181566
SBI8057407
ZMA100192647 100282753
SITA101761370
SVS117839479
PVIR120647389 120688359
PHAI112874584
PDA103703828 120103782
EGU105042568 105061201
MUS103977223 103983433 108952573
DCT110108278 110110648
PEQ110021793
AOF109838936
ATR18424175
SMOSELMODRAFT_152839(SMT2-2) SELMODRAFT_449634(SMT2-1)
PPP112289795 112294107 112294817
CRECHLRE_12g500500v5
VCNVOLCADRAFT_103647
MNGMNEG_16695
CSLCOCSUDRAFT_27964
APROF751_0617
MISMICPUN_57838
 » show all
Reference
1  [PMID:9746350]
  Authors
Bouvier-Nave P, Husselstein T, Benveniste P
  Title
Two families of sterol methyltransferases are involved in the first and the second methylation steps of plant sterol biosynthesis.
  Journal
Eur J Biochem 256:88-96 (1998)
DOI:10.1046/j.1432-1327.1998.2560088.x
  Sequence
[osa:4331540]
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.143
IUBMB Enzyme Nomenclature: 2.1.1.143
ExPASy - ENZYME nomenclature database: 2.1.1.143
BRENDA, the Enzyme Database: 2.1.1.143
CAS: 67165-89-3
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