KEGG   ENZYME: 2.4.1.159
Entry
EC 2.4.1.159                Enzyme                                 
Name
flavonol-3-O-glucoside L-rhamnosyltransferase;
uridine diphosphorhamnose-flavonol 3-O-glucoside rhamnosyltransferase;
UDP-rhamnose:flavonol 3-O-glucoside rhamnosyltransferase;
UDP-L-rhamnose:flavonol-3-O-D-glucoside 6''-O-L-rhamnosyltransferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
Sysname
UDP-beta-L-rhamnose:flavonol-3-O-beta-D-glucoside 6''-O-L-rhamnosyltransferase (configuration-inverting)
Reaction(IUBMB)
UDP-beta-L-rhamnose + a flavonol 3-O-beta-D-glucoside = UDP + a flavonol 3-O-[alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] [RN:R03880]
Reaction(KEGG)
R03880 > R04900 R12046
Substrate
UDP-beta-L-rhamnose [CPD:C02199];
flavonol 3-O-beta-D-glucoside [CPD:C03946]
Product
UDP [CPD:C00015];
flavonol 3-O-[alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] [CPD:C04194]
Comment
A configuration-inverting rhamnosyltransferase that converts flavonol 3-O-glucosides to 3-O-rutinosides. Also acts, more slowly, on rutin, quercetin 3-O-galactoside and flavonol 3-O-rhamnosides.
History
EC 2.4.1.159 created 1986, modified 2015
Pathway
ec00944  Flavone and flavonol biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K22772  flavonol-3-O-glucoside L-rhamnosyltransferase
Genes
CPAP110821584
CIT102578019
CICCICLE_v10004868mg
PVY116144158 116144201 116144250
MINC123216390
GRA105803319
GHI107912543
GAB108470982
DZI111313488
GMX100818062(FG1) 100819964(UGT79A6)
GSJ114402612
PVUPHAVU_007G135800g
VRA106769849
VAR108340918
VUN114189740
CCAJ109804959
APRC113873325
MTRMTR_1g090270 MTR_1g090280 MTR_4g059370
CAM101512184(UGT79A5)
ADU107466489
AIP107619647
AHF112711420 112779780
LANG109336024
ZJU107426658 107426669
MNT112091444 21385665 21393595 21393596
RCU8271431
HBR110646224
MESC110629343
POP7465981
PALZ118043917 118043918
TWL119999971 120000591
SLY101244316
SPEN107031550
SOT102581417
CANN107861697
NTA107767212 107781522 107831042
NSY104213556
NTO104084893
NAU109205250
INI109173663 109173664 109173666 109173669
ITR116005311 116005333
SIND105170545
OEU111379724 111382547 111405814
HAN110883900 110929816
ECAD122608525
LSV111885539
CCAV112518423
BVG104908786 104908787
SOE110803262 110803271 110803278
CQI110687785 110703425 110729297
MING122060765
TSS122651041 122672043
PSOM113279697 113296668 113300584
NCOL116247234 116247254 116247419 116247422 116247423 116247424 116247425 116248567 116249567 116251085 116254083 116254426 116254701 116254853
OSA4350462 9267603
DOSAOs11t0457300-01(Os11g0457300) Os11t0461200-01(Os11g0461200)
OBR102707242
BDI100838243 100838538
ATS109761553
TDC119344919 119362179
TAES123040456 123051358 123176859 123187305
SBI8066960 8069309 8069310
ZMA100192114
SITA101754290 101757804 101763746 101765378
SVS117866571 117866745 117866826
PVIR120643715 120650493 120658814 120686094 120686464 120686670 120706313 120711574 120713200
PDA103698348
EGU105035325 105035416
MUS103997158
DCT110100597
PEQ110020195
AOF109839485
ATR18438253
 » show all
Reference
1
  Authors
Kleinehollenhorst, G., Behrens, H., Pegels, G., Srunk, N. and Wiermann, R.
  Title
Formation of flavonol 3-O-diglycosides and flavonol 3-O-triglycosides by enzyme extracts from anthers of Tulipa cv apeldoorn - characterization and activity of 3 different O-glycosyltransferases during anther development.
  Journal
Z Natursforsch C: Biosci 37:587-599 (1982)
Reference
2  [PMID:12900416]
  Authors
Jones P, Messner B, Nakajima J, Schaffner AR, Saito K
  Title
UGT73C6 and UGT78D1, glycosyltransferases involved in flavonol glycoside biosynthesis in Arabidopsis thaliana.
  Journal
J Biol Chem 278:43910-8 (2003)
DOI:10.1074/jbc.M303523200
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.159
IUBMB Enzyme Nomenclature: 2.4.1.159
ExPASy - ENZYME nomenclature database: 2.4.1.159
BRENDA, the Enzyme Database: 2.4.1.159
CAS: 83380-89-6
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