KEGG   ENZYME: 2.4.1.354
Entry
EC 2.4.1.354                Enzyme                                 

Name
(R)-mandelonitrile beta-glucosyltransferase;
UGT85A19 (gene name)
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
Sysname
UDP-alpha-D-glucose:(R)-mandelonitrile beta-D-glucosyltransferase (configuration-inverting)
Reaction(IUBMB)
UDP-alpha-D-glucose + (R)-mandelonitrile = UDP + (R)-prunasin [RN:R10638]
Reaction(KEGG)
R10638
Substrate
UDP-alpha-D-glucose [CPD:C00029];
(R)-mandelonitrile [CPD:C00561]
Product
UDP [CPD:C00015];
(R)-prunasin [CPD:C00844]
Comment
The enzyme, characterized from Prunus dulcis (almond), is involved in the biosynthesis of the cyanogenic glycosides (R)-prunasin and (R)-amygdalin.
History
EC 2.4.1.354 created 2018
Pathway
ec00460  Cyanoamino acid metabolism
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K22706  (R)-mandelonitrile beta-glucosyltransferase
Genes
PPER: 18788923
PMUM: 103319663
PDUL: 117636363
Reference
1  [PMID:32688778]
  Authors
Franks TK, Yadollahi A, Wirthensohn MG, Guerin JR, Kaiser BN, Sedgley M, Ford CM
  Title
A seed coat cyanohydrin glucosyltransferase is associated with bitterness in almond (Prunus dulcis) kernels.
  Journal
Funct Plant Biol 35:236-246 (2008)
DOI:10.1071/FP07275
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.354
IUBMB Enzyme Nomenclature: 2.4.1.354
ExPASy - ENZYME nomenclature database: 2.4.1.354
BRENDA, the Enzyme Database: 2.4.1.354
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