KEGG ENZYME: 2.6.1.99

ENZYME: 2.6.1.99

Entry

EC 2.6.1.99                 Enzyme

Name

L-tryptophan---pyruvate aminotransferase;
TAA1 (gene name);
vt2 (gene name)

Class

Transferases;
Transferring nitrogenous groups;
Transaminases

Sysname

L-tryptophan:pyruvate aminotransferase

Reaction(IUBMB)

L-tryptophan + pyruvate = indole-3-pyruvate + L-alanine [RN:R10180]

Reaction(KEGG)

R10180

Substrate

L-tryptophan [CPD:C00078];
pyruvate [CPD:C00022]

Product

indole-3-pyruvate [CPD:C00331];
L-alanine [CPD:C00041]

Comment

This plant enzyme, along with EC 1.14.13.168, indole-3-pyruvate monooxygenase, is responsible for the biosynthesis of the plant hormone indole-3-acetate from L-tryptophan.

History

EC 2.6.1.99 created 2012

Pathway

ec00380

Tryptophan metabolism

ec01100

Metabolic pathways

Orthology

K16903

L-tryptophan---pyruvate aminotransferase

Genes

ATH:	AT1G23320(TAR1) AT1G70560(TAA1) AT4G24670(TAR2)

ALY:	9305778 9323373 9329339

CRB:	17877519 17894004 17900474

CSAT:

104701697 104712605 104720137 104722517 104730979 104743484 104750895 104759380 104778836

EUS:	EUTSA_v10009685mg EUTSA_v10018719mg EUTSA_v10025236mg

BRP:	103831591 103840774 103840776 103852664 103862382

BNA:	106353777 106374472 106375778 106395273 106400436 106404922 106430840 106442204

BOE:	106294041 106294077 106299425 106321880 106322583 106325109

RSZ:	108826645 108837372 108839658 108841769 108844999 108845011

THJ:	104809038 104809260 104822161 104822981

CPAP:

110813115 110816856

CIT:	102612766 102617510

CIC:	CICLE_v10020085mg CICLE_v10033774mg

PVY:	116118575 116124469

MINC:

123204446 123210603 123213225

TCC:	18604012 18609529

GRA:	105779160 105780852 105794631 105800025

GHI:	107886550 107890884 107898658 107898660 107909692 107933359 107933665

GAB:	108456650 108459859 108474874

HSYR:

120150625 120171162 120183225 120204573 120214034 120215285

DZI:	111282864 111287631 111287783 111290251

EGR:	104414154 104417808

RARG:

115741407 115751351

GMX:	100777098 100801447 100803246 100807013 100818522 100820582

GSJ:	114380537 114392876 114400662 114409858 114411987 114416422

PVU:	137807902 137810515 137821031

VRA:	106753302 106761959 106776775

VAR:	108327681 108331054 108333707

VUN:	114162124 114174212 114177247

VUM:	124826623 124838431 124840687 124842789

CCAJ:

109797027 109801329 109807609

APRC:

113853118 113870437 113874846

MTR:	11410630 11415573 11439449 25493735

TPRA:

123887079 123896409 123896411 123896413 123898708 123898709 123898719 123898722 123898730 123898733 123898741 123898778 123898805 123898824 123898839 123898850 123898866 123898867 123898871 123898886 123898888 123898905 123898924 123899683 123906861 123910106

CAM:	101489241 101508125 101514153

PSAT:

127073960 127083677 127119275 127121371 127121372

VVO:	131636034 131639090 131640707 131646184 131646185 131650676 131656030

LJA:	130714032 130734482 130735743 130735744 130740042

ADU:	107478928 107481141 107488755 107491447

AIP:	107609489 107632027 107633787 107640363 107641771

AHF:	112695941 112722318 112735514 112746944 112749973 112766026 112790455 112791756 112801160 112801162

LANG:

109330662 109332717 109342780 109362513

PCIN:

129290257 129309710 129321274 129322406 129323101

QSA:	O6P43_022679 O6P43_025259 O6P43_030840 O6P43_033198

FVE:	101299870 101301876 101312441

AANS:

126791764 126793831 126795121

RCN:	112176054 112180086 112199635

PPER:

18776298 18788121 18792031

PMUM:

103321820 103321907 103337916

PAVI:

110745862 110773598

PDUL:

117615674 117616625 117628571

MDM:	103403054 103437690 103455193

MSYL:

126597560 126598571 126607976 126626143

PXB:	103949799 103952975

PCOX:

137711516 137713221 137732571 137736282

ZJU:	107418305 107428581

MNT:	21397691 21410299

CSAV:

115711631 115714732

CSV:	101204502 101206126 101206363

CMO:	103483752 103502384 103502385

BHJ:	120070759 120076107 120083686

MCHA:

111004658 111007309 111008686

CMAX:

111470731 111485740 111490275 111495051 111496597

CMOS:

111429925 111431614 111432460 111454299 111457147

CPEP:

111780369 111782768 111793207 111798930 111802190

RCU:	8273485 8278313

MEAN:

126656453 126673310

JCU:

105640330

HBR:	110640704 110640705 110642579 110645893 110645901 110664765

MESC:

110627445 110631077

POP:	112324299 112328448 7456901 7492386

PEU:	105120045 105132347 105140228 105140872 105142072

PALZ:

118038235 118044886 118045457 118057452

PNZ:	133675400 133678069 133698008

JRE:	108979082 108984468 109003845

CILL:

122282695 122289610 122311305

CAVE:

132175596 132178458 132178459

AGLU:

133866196 133874568

QSU:	111990404 112010065 112013773 112037363 136070438 136071343

QLO:	115963732 115979000 115986238 115986239

TWL:	119986048 119992145 120000883

VVI:	100245885 100257504 100262049

VRI:	117904710 117912625

SLY:	101246927(TAA1) 101253797 101262607

SPEN:

107012524 107019794 107020730 107021555

SOT:	102587670 102588233 102588841 102589167 102592266 102592610 102603358

SSTN:

125856608 125856691 125857702 125867316 125867317 125872181

SDUL:

129875655 129896604 129901600

CANN:

107846935 107851600 107854124 107857351 107862570

LBB:	132601596 132632612 132642599

NTA:	107767293 107784414 107825960 107829568

NSY:	104224700 104244704

NTO:	104099725 104114980

NAU:	109211005 109223662

INI:	109160163 109177167 109190275 109190293

ITR:	116005080 116006812 116023589

SIND:

105156774 105157456 105168289 105179382

OEU:	111369186 111401708 111404891 111404892 111408458

EGT:	105950533 105967950 105975066

SSPL:

121766659 121768026 121785515 121785948 121799550 121800225

SMIL:

130993637 131019720 131019730 131025318

SHIS:

125185903 125191290 125206792 125206793 125207079 125208068 125208614 125210496 125210498

APAN:

127241180 127241701 127241702 127246153 127255147 127262685

HAN:	110868545 110891139 110915440 110925437

ECAD:

122589916 122598580

LSV:	111907020 111911344

CCAV:

112501486 112509490

DCR:	108193781 108194678 108207706

CSIN:

114259774 114271819 114301053

RVL:	131310940 131311993 131311994 131335884

AEW:	130779509 130781618 130796117

DLT:	127790523 127809925

BVG:	104894324 104897269 104897270

SOE:	110799231 110799637

CQI:	110681932 110700349 110701878 110707110 110712556 110727594

ATRI:

130797462 130807845

MOF:	131144381 131144480 131144545 131146086

NNU:	104591456 104591457 104593122 104593123 104605535 104606093

MING:

122061412 122067247 122077154

TSS:	122656370 122671631 122672037

PSOM:

113300134 113319329 113340742 113351288 113353459 113361071

OSA:	4325198(FIB) 4337930

DOSA:

Os05g0169300

OBR:	102703686 102704576

OGL:	127773340 127774429

BDI:	100824596 100838076

ATS:	109740802 109749870 109779434

TDC:	119267093 119269591 119274926 119276949 119328059 119328115 119331320 119341237 119365812

TAES:

123053434 123060273 123068780 123077285 123083178 123083188 123083217 123083248 123105817 123114279 123114319 123130433 123151276 123169461 123176510 123180651

TUA:	125515662 125515689 125519122 125522922 125542788 125551839

LPER:

127292988 127293019 127341211

LRD:	124649325 124657618 124659660 124660957

SBI:	8056556 8080939 8080940

ZMA:	100193435 100272716 100285505 103634861 103649700

MFLO:

136449518 136513420 136513515

SITA:

101756802 101762186 101784814 101785211

SVS:	117850582 117855065

PVIR:

120664256 120667426 120676435 120697551 120701227 120705864

PHAI:

112887428 112892158

PAUA:

133885086 133897196 133911407 133929717

PDA:	103700751 103703781 103711568 108511861 120104063 120104064 120104065 120104135 120104136

EGU:	105033654 105036212

MUS:	103979260 103988297 135625141

ZOF:	121967980 121971938 121976960 121982295 122019349 122023114 122053463 122055618

DCT:	110097172 110100718

PEQ:	110019338 110031026

AOF:	109828906 109844997 109845497 109845735

MSIN:

131235136

ACAK:

137936995 137940317

NCOL:

116247742

ATR:

18422576

CJF:

131044230

SMO:	SELMODRAFT_171289 SELMODRAFT_176918

PPP:	112274010 112278111 112294406 112295190

» show all

Reference

1 [PMID:18394996]

Authors

Tao Y, Ferrer JL, Ljung K, Pojer F, Hong F, Long JA, Li L, Moreno JE, Bowman ME, Ivans LJ, Cheng Y, Lim J, Zhao Y, Ballare CL, Sandberg G, Noel JP, Chory J

Title

Rapid synthesis of auxin via a new tryptophan-dependent pathway is required for shade avoidance in plants.

Journal

Cell 133:164-76 (2008)
DOI:10.1016/j.cell.2008.01.049

Sequence

[ath:AT1G70560 AT1G23320 AT4G24670]

Reference

2 [PMID:22025724]

Authors

Mashiguchi K, Tanaka K, Sakai T, Sugawara S, Kawaide H, Natsume M, Hanada A, Yaeno T, Shirasu K, Yao H, McSteen P, Zhao Y, Hayashi K, Kamiya Y, Kasahara H

Title

The main auxin biosynthesis pathway in Arabidopsis.

Journal

Proc Natl Acad Sci U S A 108:18512-7 (2011)
DOI:10.1073/pnas.1108434108

Sequence

[ath:AT1G70560]

Reference

3 [PMID:21335375]

Authors

Phillips KA, Skirpan AL, Liu X, Christensen A, Slewinski TL, Hudson C, Barazesh S, Cohen JD, Malcomber S, McSteen P

Title

vanishing tassel2 encodes a grass-specific tryptophan aminotransferase required for vegetative and reproductive development in maize.