KEGG   ENZYME: 2.7.8.3
Entry
EC 2.7.8.3                  Enzyme                                 
Name
ceramide cholinephosphotransferase;
phosphorylcholine-ceramide transferase
Class
Transferases;
Transferring phosphorus-containing groups;
Transferases for other substituted phosphate groups
Sysname
CDP-choline:N-acylsphingosine cholinephosphotransferase
Reaction(IUBMB)
CDP-choline + a ceramide = CMP + sphingomyelin [RN:R01891]
Reaction(KEGG)
R01891
Substrate
CDP-choline [CPD:C00307];
ceramide [CPD:C00195]
Product
CMP [CPD:C00055];
sphingomyelin [CPD:C00550]
History
EC 2.7.8.3 created 1965
Pathway
ec00600  Sphingolipid metabolism
ec01100  Metabolic pathways
Reference
1
  Authors
Kennedy, E.P.
  Title
Phosphorylcholine-glyceride transferase.
  Journal
Methods Enzymol 5:484-486 (1962)
Reference
2  [PMID:13610834]
  Authors
SRIBNEY M, KENNEDY EP.
  Title
The enzymatic synthesis of sphingomyelin.
  Journal
J Biol Chem 233:1315-22 (1958)
Other DBs
ExplorEnz - The Enzyme Database: 2.7.8.3
IUBMB Enzyme Nomenclature: 2.7.8.3
ExPASy - ENZYME nomenclature database: 2.7.8.3
BRENDA, the Enzyme Database: 2.7.8.3
CAS: 9026-14-6
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