ENZYME: 4.2.3.60
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Entry
EC 4.2.3.60 Enzyme
Name
germacrene C synthase
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
BRITE hierarchy
Sysname
(2E,6E)-farnesyl-diphosphate diphosphate-lyase (germacrene-C-forming)
Reaction(IUBMB)
(2E,6E)-farnesyl diphosphate = germacrene C + diphosphate [RN:
R09624
]
Reaction(KEGG)
R09624
Reaction
Substrate
(2E,6E)-farnesyl diphosphate [CPD:
C00448
]
Product
germacrene C [CPD:
C19747
];
diphosphate [CPD:
C00013
]
History
EC 4.2.3.60 created 2011
Pathway
ec00909
Sesquiterpenoid and triterpenoid biosynthesis
Orthology
K15802
germacrene C synthase
Genes
SLY
:
543549(SSTLE1)
SDUL
:
129900319
Taxonomy
Reference
1 [PMID:
9482865
]
Authors
Colby SM, Crock J, Dowdle-Rizzo B, Lemaux PG, Croteau R
Title
Germacrene C synthase from Lycopersicon esculentum cv. VFNT cherry tomato: cDNA isolation, characterization, and bacterial expression of the multiple product sesquiterpene cyclase.
Journal
Proc Natl Acad Sci U S A 95:2216-21 (1998)
DOI:
10.1073/pnas.95.5.2216
Sequence
[sly:
543549
]
Other DBs
ExplorEnz - The Enzyme Database:
4.2.3.60
IUBMB Enzyme Nomenclature:
4.2.3.60
ExPASy - ENZYME nomenclature database:
4.2.3.60
BRENDA, the Enzyme Database:
4.2.3.60
LinkDB
All DBs
DBGET
integrated database retrieval system