KEGG   ENZYME: 5.1.1.5
Entry
EC 5.1.1.5                  Enzyme                                 
Name
lysine racemase
Class
Isomerases;
Racemases and epimerases;
Acting on amino acids and derivatives
Sysname
lysine racemase
Reaction(IUBMB)
L-lysine = D-lysine [RN:R00460]
Reaction(KEGG)
R00460
Substrate
L-lysine [CPD:C00047]
Product
D-lysine [CPD:C00739]
Comment
The enzyme is involved in a lysine catabolic pathway.
History
EC 5.1.1.5 created 1961
Pathway
ec00310  Lysine degradation
ec00470  D-Amino acid metabolism
ec01100  Metabolic pathways
Orthology
K20707  lysine racemase
Genes
OOEOEOE_0162
Reference
1  [PMID:13598707]
  Authors
HUANG HT, DAVISSON JW
  Title
Distribution of lysine racemase in bacteria.
  Journal
J Bacteriol 76:495-8 (1958)
DOI:10.1128/JB.76.5.495-498.1958
Reference
2
  Authors
Huang, H.T.
  Title
dl-Lysine production by lysine racemase.
  Journal
Chem Abstr 54:20073 (1960)
Reference
3  [PMID:19502445]
  Authors
Chen IC, Lin WD, Hsu SK, Thiruvengadam V, Hsu WH
  Title
Isolation and characterization of a novel lysine racemase from a soil metagenomic library.
  Journal
Appl Environ Microbiol 75:5161-6 (2009)
DOI:10.1128/AEM.00074-09
Reference
4  [PMID:23035128]
  Authors
Kato S, Hemmi H, Yoshimura T
  Title
Lysine racemase from a lactic acid bacterium, Oenococcus oeni: structural basis of substrate specificity.
  Journal
J Biochem 152:505-8 (2012)
DOI:10.1093/jb/mvs120
  Sequence
[ooe:OEOE_0162]
Other DBs
ExplorEnz - The Enzyme Database: 5.1.1.5
IUBMB Enzyme Nomenclature: 5.1.1.5
ExPASy - ENZYME nomenclature database: 5.1.1.5
BRENDA, the Enzyme Database: 5.1.1.5
CAS: 9024-10-6
LinkDB

KEGG   REACTION: R00460
Entry
R00460                      Reaction                               
Name
lysine racemase
Definition
L-Lysine <=> D-Lysine
Equation
Reaction class
RC00302  C00047_C00739
Enzyme
5.1.1.5         5.1.1.10
Pathway
rn00310  Lysine degradation
rn00470  D-Amino acid metabolism
rn01100  Metabolic pathways
Orthology
K25316  amino-acid racemase [EC:5.1.1.10]
K25317  amino-acid racemase [EC:5.1.1.10]
Other DBs
RHEA: 22867
LinkDB

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