Entry |
|
Name |
5-formyltetrahydrofolate cyclo-ligase;
5,10-methenyltetrahydrofolate synthetase;
formyltetrahydrofolic cyclodehydrase;
5-formyltetrahydrofolate cyclodehydrase
|
Class |
Ligases;
Forming carbon-nitrogen bonds;
Cyclo-ligases
|
Sysname |
5-formyltetrahydrofolate cyclo-ligase (ADP-forming)
|
Reaction(IUBMB) |
ATP + 5-formyltetrahydrofolate = ADP + phosphate + 5,10-methenyltetrahydrofolate [RN: R02301]
|
Reaction(KEGG) |
|
Substrate |
|
Product |
|
History |
EC 6.3.3.2 created 1972
|
Pathway |
|
Orthology |
K00603 | glutamate formiminotransferase / 5-formyltetrahydrofolate cyclo-ligase |
K01934 | 5-formyltetrahydrofolate cyclo-ligase |
|
Genes |
HSA: | 100528021(ST20-MTHFS) 10588(MTHFS) |
MMU: | 100039707(Mthfsl) 107885(Mthfs) |
MAUA: | 101827735 121137010 121139104 |
TUP: | 102479076 102486098(MTHFS) |
ODA: | 120865476 120875546(MTHFS) |
CCAD: | 122435156 122455328(MTHFS) |
MYD: | 102755094 102760770(MTHFS) |
MDO: | 100013843(MTHFS) 103094764 |
ASAO: | 132762707(MTHFS) 132765074 |
EMC: | 129339102 129345756(MTHFS) |
CCAR: | 109055118 109055134 |
CAUA: | 113051924 113052007 113105672 |
CGIB: | 127961093 128017382 |
PLEP: | 121939006 121960137 |
SASA: | 106562590 106562654(mthfs) |
STRU: | 115166874 115203449 |
OKI: | 109881593 116359566 116359652 116370497 |
OKE: | 118372200(mthfs) 127923420 |
PSPA: | 121295036(mthfs) 121298891 |
ARUT: | 117428158 117429594 |
LPIC: | 129260342 129262183 |
DSI: | Dsimw501_GD11756(Dsim_GD11756) |
AALB: | 109399487 115270355 |
CINS: | 118069902 118071380 |
AGRG: | 126734255 126738395 |
LGLY: | 125230558 125234414 |
BTAB: | 109034780 109035488 109035489 109043702 109043707 |
CSEC: | 111865676 111866095 |
SGRE: | 126266954 126268286 |
LSM: | 121114014 121125866 121132157 121132324 121132655 |
RSAN: | 119376455 119377050 |
PTEP: | 107451887 107454541 122270296 |
ABRU: | 129963206 129976731 |
LPOL: | 106463170 106470752 106472854 |
CEL: | CELE_Y106G6E.4(Y106G6E.4) |
ATH: | AT1G76730(COG0212) AT5G13050(5-FCL) |
CSAT: | 104702443 104705549 104713339 104753883 104769517 |
EUS: | EUTSA_v10014312mg EUTSA_v10018779mg |
BRP: | 103830600 103846608 103850842 |
BNA: | 106353503 106353514 106372332 106372386 106383978 |
THJ: | 104803355 104804977 104810664 |
CPAP: | 110806640 110815283 |
CIT: | 102621092 102622960 102628227 |
CIC: | CICLE_v10001828mg CICLE_v10021875mg CICLE_v10032272mg |
PVY: | 116110991 116116187 116136203 116146531 |
MINC: | 123212013 123213109 123229800 |
TCC: | 18507047 18592654 18609324 |
GRA: | 105763113 105776580 105786249 |
GHI: | 107895444 107916295 107922504 107927316 107945260 121229628 |
GAB: | 108464351 108476769 108489175 |
HSYR: | 120119734 120130943 120139794 120153352 120165646 120190005 120198143 |
DZI: | 111291263 111311177 111317817 |
GMX: | 100527426 100777775 100797707 |
GSJ: | 114391169 114409775 114416497 |
CCAJ: | 109789863 109815893 |
APRC: | 113866996 113872544 |
TPRA: | 123895562 123897225 123899852 123905838 |
PSAT: | 127085131 127127628 |
VVO: | 131631864 131653053 131653058 131662544 |
ADU: | 107489068 107489313 107491607 |
AIP: | 107643450 107643545 107644957 |
AHF: | 112750125 112750212 112751947 112800912 112800999 112803014 |
LANG: | 109330358 109336983 109352302 |
PCIN: | 129293450 129309441 129311125 |
QSA: | O6P43_008081 O6P43_022775 O6P43_030930 O6P43_033089 |
FVE: | 101301189 101310705 101312983 |
RCN: | 112171255 112180537 112200112 |
PPER: | 18767862 18776910 18790045 |
PMUM: | 103321478 103336243 103338266 |
PAVI: | 110750668 110752060 110760714 |
PDUL: | 117616797 117628745 117637585 |
MSYL: | 126620978 126627316 |
PXB: | 103931674 103938451 103958794 |
CSAV: | 115708257 115709377 |
MCHA: | 111006765 111007435 |
CMAX: | 111471263 111485651 111489504 |
CMOS: | 111429770 111439257 111445648 |
CPEP: | 111780278 111793990 111809373 |
MEAN: | 126673609 126685540 |
JCU: | 105635498 105640464 105649809 |
HBR: | 110643966 110654355 110661919 |
MESC: | 110605801 110616576 |
PALZ: | 118044592 118061812 |
JRE: | 108981528 108983488 108985000 108990170 109000253 109000280 109016972 |
CILL: | 122290424 122299656 122311126 |
CAVE: | 132175422 132178444 132179758 132184226 |
QSU: | 111997040 112008643 112014162 |
QLO: | 115962471 115975534 115977876 115978672 115978674 |
VRI: | 117904519 117906207 117912250 |
SPEN: | 107015406 107015852 |
SSTN: | 125850750 125860368 |
SDUL: | 129896436 129904392 |
CANN: | 107862466 107867628 |
NTA: | 107760549 107760804 107788183 107796143 107813891 107813911 107816621 107818051 |
NSY: | 104219780 104226306 104232477 104244207 |
NTO: | 104092069 104096267 104121641 |
NAU: | 109209399 109212847 109216997 109222318 109223706 109244856 |
INI: | 109149123 109149149 109166233 |
ITR: | 116021578 116021622 116025353 |
SIND: | 105157162 105179341 |
SSPL: | 121746531 121780004 121782773 121787658 |
SMIL: | 131002775 131011639 131011672 131021279 |
SHIS: | 125203628 125215329 |
APAN: | 127255185 127257530 |
ECAD: | 122606930 122608292 |
CCAV: | 112511135 112511218 |
CSIN: | 114258761 114278755 114286654 |
SOE: | 110789517 110794467 110802890 |
CQI: | 110700488 110704251 110726550 110726552 110735682 |
ATRI: | 130797609 130800336 130824059 |
NNU: | 104587781 104599940 104608016 |
MING: | 122071887 122075136 122078143 |
PSOM: | 113287124 113331490 |
TDC: | 119299365 119308123 119353974 119363211 |
TAES: | 123044437 123052297 123111044 123120077 123188109 |
LPER: | 127299705 127332902 |
LRD: | 124653417 124673150 124676622 |
MFLO: | 136481101 136490649 136491918 136504485 136552600 |
SITA: | 101762244 101768067 |
PVIR: | 120661784 120692710 120696813 |
PHAI: | 112882370 112884719 |
MUS: | 103983010 135615032 135616535 |
ZOF: | 122019835 122022240 122023580 122053230 |
DCT: | 110102170 110108633 110109527 |
PEQ: | 110020017 110026165 110037554 |
MSIN: | 131226285 131231922 |
ACAK: | 137939020 137943946 137955465 |
NCOL: | 116251058 116258458 116264370 |
SMO: | SELMODRAFT_186907 SELMODRAFT_25537 SELMODRAFT_25619 SELMODRAFT_430751 SELMODRAFT_56116 SELMODRAFT_56118 SELMODRAFT_88014 |
PPP: | 112279522 112289191 112295366 |
CRE: | CHLRE_09g403293v5 CHLRE_13g587450v5 |
VCN: | VOLCADRAFT_80342(fcl2) |
CVR: | CHLNCDRAFT_136024 CHLNCDRAFT_144075 |
MIS: | MICPUN_62259 MICPUN_71689 |
CME: | CYME_CMH212C CYME_CMM112C |
CGR: | 2887631(GVI51_F08723) |
NCS: | NCAS_0B07850(NCAS0B07850) |
NDI: | NDAI_0D03460(NDAI0D03460) |
TPF: | TPHA_0C00140(TPHA0C00140) |
TBL: | TBLA_0A10710(TBLA0A10710) |
TDL: | TDEL_0D00290(TDEL0D00290) |
KAF: | KAFR_0B07020(KAFR0B07020) |
KNG: | KNAG_0M00150(KNAG0M00150) |
LBG: | 92207949(LODBEIA_P27530) |
CAL: | CAALFM_C102020WA(CaO19.4523) |
CTEN: | 18247481(PSN45_004454) |
PKZ: | C5L36_0A12200 C5L36_0D04770 |
YLI: | 2910453(YALI2_D00025g) |
NTE: | NEUTE1DRAFT116436(NEUTE1DRAFT_116436) |
SMP: | 10807613(SMAC4_00995) |
TATV: | 25783892(TrAtP1_001475) |
TASP: | 36611644(TrAFT101_001037) |
MAW: | 19245663(J3458_001851) |
MBRN: | 26237774(G6M90_00g022240) |
PLJ: | 28888381(PLICBS_003580) |
CDET: | 87944927(CDEST_08424) |
PFY: | PFICI_04437 PFICI_06794 |
SSL: | SS1G_07898 SS1G_09961 |
BFU: | BCIN_07g04310(Bcfau1) BCIN_15g01080 |
PSCO: | LY89DRAFT_129900 LY89DRAFT_596183 |
CPW: | 9690505(D8B26_004465) |
PNO: | SNOG_01017 SNOG_13666 |
PTRR: | 6345157(PtrM4_045280) 6349596(PtrM4_071140) |
BZE: | COCCADRAFT_111475 COCCADRAFT_23692 |
BSC: | COCSADRAFT_313785 COCSADRAFT_87547 |
BOR: | COCMIDRAFT_101678 COCMIDRAFT_8912 |
AALT: | CC77DRAFT_1054807 CC77DRAFT_983251 |
ARAB: | EKO05_0003923 EKO05_0011117 |
CDEP: | 91087018(L203_102807) |
KMG: | 30161042(I203_105413) |
KNE: | 92183933(IAR55_006675) |
CCAC: | CcaHIS019_0200600(CcaverHIS019_0200600) |
ABP: | AGABI1DRAFT44549(AGABI1DRAFT_44549) |
ABV: | AGABI2DRAFT73919(AGABI2DRAFT_73919) |
SCM: | SCHCO_02513432(SCHCODRAFT_02513432) |
PGR: | PGTG_15714 PGTG_16449 PGTG_18175 |
FCY: | FRACYDRAFT_186985 FRACYDRAFT_249129 |
TPS: | THAPSDRAFT_5636 THAPS_15961 |
EHX: | EMIHUDRAFT_357748 EMIHUDRAFT_365451 EMIHUDRAFT_54227 EMIHUDRAFT_54275 |
GTT: | GUITHDRAFT_65938 GUITHDRAFT_72886 |
ECOO: | ECRM13514_3771(ygfA) |
ECOH: | ECRM13516_3632(ygfA) |
EDJ: | ECDH1ME8569_2813(ygfA) |
ECOI: | ECOPMV1_03183(ygfA) |
RTG: | NCTC13098_01049(ygfA) |
CLAP: | NCTC11466_00611(ygfA) |
AHN: | NCTC12129_04104(ygfA) |
PSHI: | SAMEA2665130_2384(ygfA) |
SFJ: | SAMEA4384070_4050(ygfA) |
SOF: | NCTC11214_02698(ygfA) |
BAPF: | BUMPF009_CDS00188(ygfa) |
BAPG: | BUMPG002_CDS00188(ygfa) |
BAPU: | BUMPUSDA_CDS00188(ygfa) |
BAPW: | BUMPW106_CDS00188(ygfa) |
TPTY: | NCTC11468_00752(ygfA) |
LRI: | NCTC12151_00547(ygfA) |
RPNE: | NCTC8284_03665 NCTC8284_03666 |
XPH: | XppCFBP6546_17165(XppCFBP6546P_17165) |
VPL: | SA104470976_00349(ygfA) |
PPUD: | DW66_5452 DW66_5572 |
MCUN: | NCTC10297_01264(ygfA) |
SCAA: | TUM17387_08510(ygfA) |
LCJ: | NCTC11976_03294(fthC) |
MISZ: | MishRS11D_15580(ygfA) |
TIB: | THMIRHAM_14260(ygfA) |
RHEI: | ATY27_05785 ATY27_11160 |
TNI: | TVNIR_1056(ygfA_[C]) |
GAI: | IMCC3135_29655(ygfA) |
HAAH: | HALA3H3_360019(ygfA) |
AEL: | NCTC12917_02560(ygfA) |
CDIZ: | CEDIAZO_00895(ygfA) |
NWE: | SAMEA3174300_1549(ygfA) |
REH: | H16_A0249(h16_A0249) |
LMIR: | NCTC12852_00334(ygfA) |
OTK: | C6570_03550 C6570_06565 |
RDP: | RD2015_647 RD2015_651 |
ROI: | N4261_03515 N4261_03535 |
KIA: | G8A07_04800 G8A07_04820 |
PKT: | AT984_00340 AT984_00380 |
PAQA: | K9V56_020225 K9V56_020250 |
PAIS: | PFX98_10765 PFX98_10790 |
MIU: | ABE85_19730 ABE85_19750 |
RGU: | A4W93_03040 A4W93_03050 |
MLN: | A9174_06205 A9174_23350 |
MCI: | Mesci_1251 Mesci_3681 |
MCIC: | A4R28_08190 A4R28_20410 |
MOP: | Mesop_1279 Mesop_4564 |
MAM: | Mesau_01289 Mesau_04193 |
MAMO: | A6B35_02110 A6B35_19560 |
MESW: | A9K65_006445 A9K65_019795 A9K65_021165 |
MESM: | EJ066_05220 EJ066_24010 |
MESP: | C1M53_13825 C1M53_25140 |
MHUA: | MCHK_2146 MCHK_5270 |
MJR: | EB229_06400 EB229_23405 |
MERD: | EB233_06355 EB233_20180 |
MESR: | FGU64_03340 FGU64_13605 |
MOH: | IHQ72_05830 IHQ72_22225 |
MMEI: | LRP31_05915 LRP31_22040 |
MESJ: | MJ8_33250 MJ8_60240 |
MESI: | LGH82_03475 LGH82_03990 LGH82_21905 |
NIY: | FQ775_06190 FQ775_07470 FQ775_17375 |
NKI: | KW403_01080 KW403_05570 |
NRH: | T8J41_08495 T8J41_13610 |
MESO: | BSQ44_16985 BSQ44_23435 BSQ44_23950 |
CHEA: | PVE73_03125 PVE73_21365 |
AAK: | AA2016_1448 AA2016_5759 |
AMIH: | CO731_01408 CO731_05589 |
AMIS: | Amn_48930 Amn_pa02580 |
ANJ: | AMD1_1446 AMD1_PA0140 |
ORM: | HTY61_01640 HTY61_14040 HTY61_19285 |
PMOB: | HG718_02000 HG718_10635 |
PECT: | BN1012_Phect2122 BN1012_Phect700 |
SMK: | Sinme_2813 Sinme_3406 |
SMQ: | SinmeB_2589 SinmeB_3181 |
SMX: | SM11_chr2922 SM11_chr3546 |
SMI: | BN406_02615 BN406_03210 |
SMEG: | C770_GR4Chr0083 C770_GR4Chr2883 |
SMEL: | SM2011_c02594 SM2011_c03974 |
SMER: | DU99_00415 DU99_15270 |
SIX: | BSY16_2969 BSY16_3923 |
EMX: | FKV68_17550 FKV68_25120 |
SKM: | PZL22_003061 PZL22_003690 |
STEG: | QA637_13965 QA637_19540 |
RTR: | RTCIAT899_CH14725 RTCIAT899_PC01810 |
RHR: | CKA34_17565 CKA34_29285 |
RHIB: | I8E17_12640 I8E17_27950 |
SZO: | K8M09_13515 K8M09_18845 |
SOJ: | K6301_11590 K6301_15710 |
SSUM: | Q9314_09865 Q9314_14970 |
HOE: | IMCC20628_00425 IMCC20628_00857 |
OIN: | IAR37_00270 IAR37_20245 IAR37_20265 |
OAN: | Oant_1194 Oant_2976 Oant_2980 |
OAH: | DR92_3524 DR92_3528 DR92_747 |
BPSN: | NIK97_07195 NIK97_15055 NIK97_15075 |
BRUC: | LJ361_08665 LJ361_08685 LJ361_20685 |
OCR: | HGK82_10140 HGK82_18000 HGK82_18020 |
OCL: | GTN27_10370 GTN27_19845 GTN27_19865 |
BEZ: | NCTC12898_01300(ygfA) |
LNE: | FZC33_16130 FZC33_22700 |
MEA: | Mex_1p2364 Mex_1p3770 |
MDI: | METDI0883 METDI3144 METDI4492 |
MET: | M446_1294 M446_2902 M446_3072 |
METS: | DK389_02170 DK389_03650 DK389_07585 |
MMES: | MMSR116_12855 MMSR116_29725 |
MTAD: | M6G65_27320 M6G65_30930 |
MTUN: | MTUNDRAET4_2747 MTUNDRAET4_3756 |
HNI: | W911_06225 W911_08375 |
FIL: | BN1229_v1_0221 BN1229_v1_0522 BN1229_v1_2110 BN1229_v1_2507 |
FIY: | BN1229_v1_0225 BN1229_v1_0525 BN1229_v1_2110 BN1229_v1_3408 |
RHZ: | RHPLAN_18530 RHPLAN_27140 |
PLEO: | OHA_1_03702 OHA_1_04340 |
HDI: | HDIA_3221 HDIA_3226 HDIA_3437 HDIA_3630 |
MEY: | TM49_06850 TM49_06870 TM49_12880 |
NOH: | G5V57_03430 G5V57_15020 |
BRN: | D1F64_06555 D1F64_19610 |
LAP: | ACP90_04810 ACP90_19380 |
LABT: | FIU93_10450 FIU93_25935 |
LAGG: | B0E33_03060 B0E33_16370 |
LIZ: | LGH83_11545 LGH83_15455 |
RUT: | FIU92_11870 FIU92_18000 FIU92_21015 |
LMD: | METH_01460 METH_05985 |
MALG: | MALG_00854 MALG_04633 |
SINL: | DSM14862_00909 DSM14862_02636(ygfA) |
SDUB: | R1T39_06755 R1T39_16980 |
SPSE: | SULPSESMR1_00634 SULPSESMR1_04489 SULPSESMR1_04518 |
RMM: | ROSMUCSMR3_01224 ROSMUCSMR3_03826 |
ROK: | RAK1035_0172 RAK1035_2672 |
ROH: | FIU89_01195 FIU89_06665 |
RPEL: | N7U68_05990 N7U68_19890 |
AHT: | ANTHELSMS3_04288(ygfA) |
MALU: | KU6B_37100 KU6B_57340 |
TGL: | HFZ77_03270 HFZ77_07065 |
PALX: | GQA70_05185 GQA70_13000 |
PZH: | CX676_07925 CX676_21035 |
PARU: | CYR75_01655 CYR75_06410 |
PPAN: | ESD82_09535 ESD82_16550 |
PSTL: | JHW45_02255 JHW45_10145 |
TSCO: | R1T40_08160 R1T40_18135 |
THW: | BMG03_07090 BMG03_19965 |
TEC: | AKL02_003505 AKL02_005980 AKL02_017720 |
LVS: | LOKVESSMR4R_01105 LOKVESSMR4R_02148 |
GEH: | HYN69_11435 HYN69_12030 |
SALO: | EF888_10655 EF888_21045 |
PSEB: | EOK75_13710 EOK75_14685 |
PAED: | G5B38_04265 G5B38_17890 |
MON: | G8E03_02805 G8E03_05750 |
PPAF: | I8N54_07230 I8N54_13185 I8N54_13200 |
PGV: | SL003B_0912 SL003B_1960 SL003B_4141 |
THAS: | C6Y53_01605 C6Y53_06135 C6Y53_18605 |
HDH: | G5B40_04005 G5B40_05350 G5B40_06225 |
GYJ: | AADW23_17155 AADW23_17850 |
AALK: | LGT41_0013730 LGT41_0013955 |
AMAQ: | GO499_10615 GO499_19315 |
PBAE: | P8S53_08070 P8S53_18140 P8S53_18155 |
LVR: | T8T21_06765 T8T21_18115 T8T21_18235 |
FAQ: | G5B39_06335 G5B39_07925 |
SINR: | O5O51_05800 O5O51_10350 |
RHP: | LPB142_00740 LPB142_06120 |
SFLA: | SPHFLASMR4Y_01136(ygfA) |
ACOB: | P0Y56_02540 P0Y56_05265 |
RMT: | IAI58_12045 IAI58_19765 |
SHUM: | STHU_37760 STHU_49870 |
HTQ: | FRZ44_31980 FRZ44_41300 FRZ44_47570 |
HADH: | FRZ61_15680 FRZ61_39480 |
THAR: | T8K17_02415 T8K17_12310 |
ATX: | GCD22_00834(busg_396) |
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