KEGG   ORTHOLOGY: K00603
Entry
K00603                      KO                                     

Symbol
fctD
Name
glutamate formiminotransferase / 5-formyltetrahydrofolate cyclo-ligase [EC:2.1.2.5 6.3.3.2]
Pathway
map00340  Histidine metabolism
map00670  One carbon pool by folate
map01100  Metabolic pathways
Module
M00045  Histidine degradation, histidine => N-formiminoglutamate => glutamate
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00340 Histidine metabolism
    K00603  fctD; glutamate formiminotransferase / 5-formyltetrahydrofolate cyclo-ligase
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    K00603  fctD; glutamate formiminotransferase / 5-formyltetrahydrofolate cyclo-ligase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.5  glutamate formimidoyltransferase
     K00603  fctD; glutamate formiminotransferase / 5-formyltetrahydrofolate cyclo-ligase
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.3  Cyclo-ligases
    6.3.3.2  5-formyltetrahydrofolate cyclo-ligase
     K00603  fctD; glutamate formiminotransferase / 5-formyltetrahydrofolate cyclo-ligase
Other DBs
RN: R02287 R02301 R03189
COG: COG3643
GO: 0030409 0030272
Genes
BBAY: A4V04_09620
DML: Dmul_14120(ftcD1)
DMM: dnm_068630(ftcD)
SAT: SYN_00461
HNI: W911_06225
FIL: BN1229_v1_0522
FIY: BN1229_v1_0525
SPY: SPy_2083
SPZ: M5005_Spy1772
SPYM: M1GAS476_1820
SPYA: A20_1815(ftcD)
SPS: SPs1771
SPF: SpyM51730
STG: MGAS15252_1616(fctD)
STX: MGAS1882_1677(fctD)
STZ: SPYALAB49_001753(ftcD)
SPYH: L897_08810
SSA: SSA_0434
SGO: SGO_1806(ftcD)
SDS: SDEG_2057
SDA: GGS_1889
SDC: SDSE_2157(FTCD)
STK: STP_0392
SCP: HMPREF0833_11149(ftcD)
SCF: Spaf_1717
SIK: K710_1368
SKI: D7D50_05080(ftcD)
ETH: CK496_05180(ftcD)
VCP: H9L18_10740(ftcD)
VHY: G7082_10050(ftcD)
CTC: CTC_02305
CSQ: CSCA_3654
CALE: FDN13_08360(ftcD)
CRS: FQB35_01070(ftcD) FQB35_12570(ftcD) FQB35_13075(ftcD)
CPRF: K7H06_14430(ftcD) K7H06_17205(ftcD)
CAZO: G3A45_08665(ftcD)
BHAN: CGC63_11335(ftcD)
BLAU: DQQ01_11205(ftcD)
CSO: CLS_36910
PBIF: KXZ80_02950(ftcD) KXZ80_09885(ftcD)
PBQ: C3V37_06710(ftcD)
STH: STH3192
SALQ: SYNTR_1301
SAY: TPY_0925
VGU: HYG85_18620(ftcD)
VPY: HZI73_17935(ftcD)
ACAE: HYG86_08725(ftcD)
AMIJ: EQM06_00460(ftcD)
AMIC: Ami3637_06870(ftcD)
ABUT: Ami103574_01595(ftcD)
TTE: TTE0450
THX: Thet_0437
TIT: Thit_0420
CHY: CHY_0695(ftcD)
TPZ: Tph_c20440(ftcd)
TTM: Tthe_2241
TSH: Tsac_0044
TOC: Toce_1474
CAD: Curi_c03010(ftcD)
SPOA: EQM13_04095(ftcD)
KPAR: JL105_06140(ftcD)
SEDZ: JYG23_06485(ftcD)
PUF: UFO1_4407
PFT: JBW_02658
AIN: Acin_0279
CWO: Cwoe_3011
AFO: Afer_0329
GLJ: GKIL_4221
TDE: TDE_0296
TPED: TPE_0827
TPHG: FUT81_11925(ftcD)
ACA: ACP_0519(ftcD)
GRW: FTO74_06925(ftcD)
TALB: FTW19_15490(ftcD)
ABAS: ACPOL_1045
EDA: GWR55_04165(ftcD)
CVL: J8C06_02265(ftcD)
CHLO: J8C02_09390(ftcD)
FPD: CTM68_09850(ftcD)
FGO: C4N16_03620(ftcD)
FNF: BSQ88_01990(ftcD)
FPEI: C4N17_03035(ftcD)
FCI: I6I83_07900(ftcD) I6I83_10065(ftcD)
TAI: Taci_0915
TLI: Tlie_0373
BTH: BT_2693
BFR: BF4147
BFS: BF9343_3864(ftcD)
BFG: BF638R_4006(ftcD)
BXY: BXY_18190
BZG: C4H11_10240(ftcD)
BHF: C3V43_06990(ftcD)
BIS: DXK01_007975(ftcD)
BVU: BVU_0334
PGI: PG_0329
PGN: PGN_1633
PBT: ING2E5B_1142(ftcd)
PSAC: PSM36_1609(ftcd)
PDI: BDI_3645
PARC: CI960_01370(ftcD)
TFO: BFO_0770(ftcD)
TOH: BCB71_03440(ftcD)
TMA: TM0843
TMW: THMA_0864
TMQ: THMB_0864
TMX: THMC_0864
TPT: Tpet_0084
TRQ: TRQ2_0084
TNA: CTN_1732
TNP: Tnap_0084
TLE: Tlet_1282
TME: Tmel_1173
TAF: THA_1560(ftcD)
THER: Y592_06750
FNO: Fnod_0808
DTN: DTL3_1345(ftcd) DTL3_1638
KOL: Kole_1720
ASAC: ATHSA_1311
CEX: CSE_13370
TAC: Ta1476
TVO: TVG0092631(TVG0092631)
PTO: PTO1242
FAI: FAD_1385
CDIV: CPM_0208
BARC: AOA65_0374
 » show all
Reference
  Authors
Jeanguenin L, Lara-Nunez A, Pribat A, Mageroy MH, Gregory JF 3rd, Rice KC, de Crecy-Lagard V, Hanson AD
  Title
Moonlighting glutamate formiminotransferases can functionally replace 5-formyltetrahydrofolate cycloligase.
  Journal
J Biol Chem 285:41557-66 (2010)
DOI:10.1074/jbc.M110.190504
  Sequence
[spy:SPy_2083]
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