Entry |
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Name |
biotin---[methylcrotonoyl-CoA-carboxylase] ligase;
biotin-[methylcrotonoyl-CoA-carboxylase] synthetase;
biotin-beta-methylcrotonyl coenzyme A carboxylase synthetase;
beta-methylcrotonyl coenzyme A holocarboxylase synthetase;
holocarboxylase-synthetase
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Class |
Ligases;
Forming carbon-nitrogen bonds;
Other carbon-nitrogen ligases
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Sysname |
biotin:apo-[3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] ligase (AMP-forming)
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Reaction(IUBMB) |
ATP + biotin + apo-[3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] = AMP + diphosphate + [3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] [RN: R04604]
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Reaction(KEGG) |
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Substrate |
ATP [CPD: C00002];
biotin [CPD: C00120];
apo-[3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] [CPD: C04827]
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Product |
AMP [CPD: C00020];
diphosphate [CPD: C00013];
[3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] [CPD: C04801]
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History |
EC 6.3.4.11 created 1972
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Pathway |
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Orthology |
K01942 | biotin---protein ligase |
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Genes |
ORO: | 101363115 101368585(HLCS) |
BOM: | 102275692 102276987(HLCS) |
BIU: | 109561544(HLCS) 109563420 |
PCAD: | 102981930(HLCS) 114485348 |
ETL: | 114070498(HLCS) 114071342 114072950 |
BGAR: | 122930793 122932980 |
CGIB: | 128013317 128020687 128020931 |
AOCE: | 111587326 111587992 |
PKI: | 111855789 111858423(hlcs) |
ARUT: | 117406319 117407164 |
DSI: | Dsimw501_GD19789(Dsim_GD19789) |
CQU: | CpipJ_CPIJ007071 CpipJ_CPIJ007072 |
ACEP: | 105619994 105625408 |
BMAN: | 114239389 114249541 |
NLU: | 111048036 111050202 111058010 |
NAI: | NECAME_13093 NECAME_13444 |
PMAX: | 117336082 117339376 |
MMER: | 123537203 123552941 |
XEN: | 124441389 124441538 124441541 124441869 124442559 124442932 |
ATH: | AT1G37150(HCS2) AT2G25710(HCS1) |
CSAT: | 104703109 104714038 104752205 104752216 |
EUS: | EUTSA_v10004827mg EUTSA_v10027838mg |
BNA: | 106368386 106392404 106409576 |
RSZ: | 108805431 108830160 108830804 |
MINC: | 123203292 123206093 123229157 |
PXB: | 103933707 103956690 103956969 |
ZJU: | 107406813 107407500 107434996 |
CPEP: | 111780897 111808204 |
QSU: | 111992009 112036837 112037475 |
CANN: | 107850582 107866583 |
INI: | 109160079 109177408 109183075 109183459 |
SSPL: | 121786473 121811335 |
APAN: | 127246467 127249831 |
CSIN: | 114266663 114315283 |
PSOM: | 113346420 113356494 |
DOSA: | Os02t0167000-00(Os02g0167000) |
TAES: | 123132409 123136485 123143975 |
SITA: | 101752965 101769375 |
SMO: | SELMODRAFT_80973 SELMODRAFT_88773 |
CRE: | CHLRE_09g406000v5 CHLRE_12g508852v5 |
CVR: | CHLNCDRAFT_135977 CHLNCDRAFT_26827 |
NCS: | NCAS_0A13910(NCAS0A13910) |
NDI: | NDAI_0A02120(NDAI0A02120) |
TPF: | TPHA_0A03060(TPHA0A03060) |
TBL: | TBLA_0F02180(TBLA0F02180) |
TDL: | TDEL_0C02310(TDEL0C02310) |
KAF: | KAFR_0B01050(KAFR0B01050) |
KNG: | KNAG_0C03960(KNAG0C03960) |
CAL: | CAALFM_CR10620CA(CaO19.7645) |
COT: | CORT_0A05280 CORT_0D00250 |
NTE: | NEUTE1DRAFT124604(NEUTE1DRAFT_124604) |
BFU: | BCIN_01g05670(Bcbpl1) |
ANG: | ANI_1_850144(An16g06410) |
ABP: | AGABI1DRAFT114677(AGABI1DRAFT_114677) |
ABV: | AGABI2DRAFT226601(AGABI2DRAFT_226601) |
SCM: | SCHCO_02597546(SCHCODRAFT_02597546) |
» show all
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Reference |
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Authors |
Hopner T, Knappe J. |
Title |
[Synthesis of biotin in beta-methylcrotonyl-CoA-carboxylase by holocarboxylase synthetase] |
Journal |
Biochem Z 342:190-206 (1965) |
Other DBs |
ExplorEnz - The Enzyme Database: | 6.3.4.11 |
ExPASy - ENZYME nomenclature database: | 6.3.4.11 |
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LinkDB |
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