| Entry |
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| Symbol |
PLAU, ATF, BDPLT5, QPD, UPA, URK, u-PA
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| Name |
(RefSeq) plasminogen activator, urokinase
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| KO |
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| Organism |
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| Pathway |
| hsa04610 | Complement and coagulation cascades |
| hsa05202 | Transcriptional misregulation in cancer |
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| Network |
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| Element |
| N00128 | TMPRSS2-ERG fusion to transcriptional activation |
| N00130 | TMPRSS2-ETV5 fusion to transcriptional activation |
| N01520 | Regulation of fibrinolytic system, C1INH |
| N01523 | Regulation of fibrinolytic system, AAT |
| N01524 | Regulation of fibrinolytic system, PAI |
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| Disease |
| H01235 | Bleeding disorder platelet-type |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
5328 (PLAU)
09150 Organismal Systems
09151 Immune system
04610 Complement and coagulation cascades
5328 (PLAU)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
5328 (PLAU)
05206 MicroRNAs in cancer
5328 (PLAU)
05205 Proteoglycans in cancer
5328 (PLAU)
09162 Cancer: specific types
05215 Prostate cancer
5328 (PLAU)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:hsa01002]
5328 (PLAU)
09183 Protein families: signaling and cellular processes
00536 Glycosaminoglycan binding proteins [BR:hsa00536]
5328 (PLAU)
Enzymes [BR:hsa01000]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.21 Serine endopeptidases
3.4.21.73 u-plasminogen activator
5328 (PLAU)
Peptidases and inhibitors [BR:hsa01002]
Serine peptidases
Family S1: chymotrypsin family
5328 (PLAU)
Glycosaminoglycan binding proteins [BR:hsa00536]
Heparan sulfate / Heparin
Coagulation and fibrinolysis
5328 (PLAU)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| LinkDB |
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| Position |
10:73908832..73917494
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| AA seq |
431 aa
MRALLARLLLCVLVVSDSKGSNELHQVPSNCDCLNGGTCVSNKYFSNIHWCNCPKKFGGQ
HCEIDKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHN
YCRNPDNRRRPWCYVQVGLKLLVQECMVHDCADGKKPSSPPEELKFQCGQKTLRPRFKII
GGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLG
RSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICL
PSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKML
CAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIR
SHTKEENGLAL |
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| NT seq |
1296 nt +upstreamnt +downstreamnt
atgagagccctgctggcgcgcctgcttctctgcgtcctggtcgtgagcgactccaaaggc
agcaatgaacttcatcaagttccatcgaactgtgactgtctaaatggaggaacatgtgtg
tccaacaagtacttctccaacattcactggtgcaactgcccaaagaaattcggagggcag
cactgtgaaatagataagtcaaaaacctgctatgaggggaatggtcacttttaccgagga
aaggccagcactgacaccatgggccggccctgcctgccctggaactctgccactgtcctt
cagcaaacgtaccatgcccacagatctgatgctcttcagctgggcctggggaaacataat
tactgcaggaacccagacaaccggaggcgaccctggtgctatgtgcaggtgggcctaaag
ctgcttgtccaagagtgcatggtgcatgactgcgcagatggaaaaaagccctcctctcct
ccagaagaattaaaatttcagtgtggccaaaagactctgaggccccgctttaagattatt
gggggagaattcaccaccatcgagaaccagccctggtttgcggccatctacaggaggcac
cgggggggctctgtcacctacgtgtgtggaggcagcctcatcagcccttgctgggtgatc
agcgccacacactgcttcattgattacccaaagaaggaggactacatcgtctacctgggt
cgctcaaggcttaactccaacacgcaaggggagatgaagtttgaggtggaaaacctcatc
ctacacaaggactacagcgctgacacgcttgctcaccacaacgacattgccttgctgaag
atccgttccaaggagggcaggtgtgcgcagccatcccggactatacagaccatctgcctg
ccctcgatgtataacgatccccagtttggcacaagctgtgagatcactggctttggaaaa
gagaattctaccgactatctctatccggagcagctgaaaatgactgttgtgaagctgatt
tcccaccgggagtgtcagcagccccactactacggctctgaagtcaccaccaaaatgctg
tgtgctgctgacccacagtggaaaacagattcctgccagggagactcagggggacccctc
gtctgttccctccaaggccgcatgactttgactggaattgtgagctggggccgtggatgt
gccctgaaggacaagccaggcgtctacacgagagtctcacacttcttaccctggatccgc
agtcacaccaaggaagagaatggcctggccctctga |
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