KEGG   COMPOUND: C08073
Entry
C08073                      Compound                               
Name
Natamycin;
Pimaricin
Formula
C33H47NO13
Exact mass
665.3047
Mol weight
665.72
Structure
Sequence
0 Mak  1 Mad  2 Mad  3 Mad  4 Mad  5 Mak  6 Mak  7 Mtk  8 Man
9 Mak  10 Mad  11 Mad  12 Man
  Gene
0 pimS0 [UP:Q9X992]; 1-4 pimS1 [UP:Q9X993]; 5-10 pimS2
[UP:Q9EWA1]; 11 pimS3 [UP:Q9EWA2]; 12 pimS4 [UP:Q9EWA3]
  Organism
Streptomyces natalensis
  Type
PK
Remark
Same as: D00884
Pathway
map01052  Type I polyketide structures
Brite
Lipids [BR:br08002]
 PK  Polyketides
  PK06 Polyenes
   C08073  Natamycin
Pesticides [BR:br08007]
 Pesticides
  Fungicides
   Antibiotic fungicides
    C08073  Natamycin
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A01 STOMATOLOGICAL PREPARATIONS
   A01A STOMATOLOGICAL PREPARATIONS
    A01AB Antiinfectives and antiseptics for local oral treatment
     A01AB10 Natamycin
      D00884  Natamycin (USP/INN) <JP/US>
  A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
   A07A INTESTINAL ANTIINFECTIVES
    A07AA Antibiotics
     A07AA03 Natamycin
      D00884  Natamycin (USP/INN) <JP/US>
 D DERMATOLOGICALS
  D01 ANTIFUNGALS FOR DERMATOLOGICAL USE
   D01A ANTIFUNGALS FOR TOPICAL USE
    D01AA Antibiotics
     D01AA02 Natamycin
      D00884  Natamycin (USP/INN) <JP/US>
 G GENITO URINARY SYSTEM AND SEX HORMONES
  G01 GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
   G01A ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
    G01AA Antibiotics
     G01AA02 Natamycin
      D00884  Natamycin (USP/INN) <JP/US>
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA10 Natamycin
      D00884  Natamycin (USP/INN) <JP/US>
USP drug classification [BR:br08302]
 Ophthalmic Agents
  Ophthalmic Anti-Infectives
   Antifungal, Ophthalmic
    Natamycin
     D00884  Natamycin (USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  13  Agents affecting sensory organs
   131  Ophthalmic agents
    1317  Ophthalmic antibiotics
     D00884  Natamycin (USP/INN); Pimaricin (JP18)
Antimicrobials [BR:br08307]
 Antifungals
  Cell membrane function inhibitor
   Polyene macrolide
    D00884  Natamycin (USP/INN) <JP/US>
Antimicrobials abbreviations [BR:br08327]
 Antifungals
  Cell membrane function inhibitor
   Polyene macrolide
    D00884  Natamycin (USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00884  Pimaricin
Other DBs
CAS: 7681-93-8
PubChem: 10273
ChEBI: 7488
NIKKAJI: J3.429K
LinkDB
KCF data

ATOM        47
            1   C1y C    20.2721  -19.1041
            2   O2x O    19.0545  -18.4075
            3   C1y C    17.8390  -19.1074
            4   C1y C    17.8409  -20.5110
            5   C1y C    19.0583  -21.2148
            6   C1y C    20.2739  -20.5078
            7   C1y C    19.0687  -12.8201
            8   C1y C    19.0687  -14.2205
            9   C1y C    20.2852  -14.9172
            10  O2x O    21.4877  -14.2205
            11  C1z C    21.4877  -12.8201
            12  C1x C    20.2852  -12.1163
            13  C1b C    22.6928  -12.1163
            14  C1c C    23.9032  -12.8130
            15  C1b C    25.1134  -12.1094
            16  C1y C    26.3239  -12.8061
            17  C1y C    27.5343  -12.1023
            18  C2b C    28.7446  -12.7990
            19  C2b C    29.9479  -12.0952
            20  O6a O    32.3688  -12.0883
            21  C1b C    20.2871  -16.3175
            22  C1c C    21.4947  -17.0197
            23  C2b C    22.6998  -16.3105
            24  C2b C    23.9101  -17.0141
            25  C2b C    25.1205  -16.3105
            26  C2b C    26.3310  -17.0141
            27  C2b C    27.5412  -16.3105
            28  C2b C    28.7517  -17.0141
            29  C2b C    29.9550  -16.3105
            30  C2b C    31.1654  -17.0141
            31  C1b C    32.3057  -16.3105
            32  C1c C    32.3688  -14.9101
            33  O7a O    31.1516  -14.2195
            34  C7a C    31.1443  -12.8130
            35  O2x O    26.3168  -11.4057
            36  O1a O    23.8961  -14.2134
            37  O1a O    21.4754  -11.4197
            38  O2a O    21.4823  -18.4146
            39  C1a C    33.5790  -14.2063
            40  O1a O    17.8512  -12.1163
            41  C6a C    17.8512  -14.9101
            42  O1a O    16.6198  -21.2012
            43  N1a N    19.0601  -22.6150
            44  O1a O    21.4815  -21.2099
            45  C1a C    16.6244  -18.4124
            46  O6a O    16.6416  -14.2065
            47  O6a O    17.8433  -16.3105
BOND        50
            1    12   7 1
            2    24  25 1
            3     6   1 1
            4    25  26 2
            5    11  13 1
            6    26  27 1
            7    27  28 2
            8    13  14 1
            9    28  29 1
            10    1   2 1
            11   29  30 2
            12   14  15 1
            13   30  31 1
            14    2   3 1
            15   31  32 1
            16   15  16 1
            17   32  33 1
            18    3   4 1
            19   33  34 1
            20   16  17 1
            21   16  35 1
            22   17  35 1
            23    4   5 1
            24   14  36 1 #Down
            25   17  18 1
            26   11  37 1 #Down
            27    5   6 1
            28   18  19 2
            29   22  38 1 #Down
            30   19  34 1
            31   32  39 1 #Down
            32    7   8 1
            33    7  40 1 #Up
            34   34  20 2
            35    8  41 1 #Down
            36   38   1 1
            37    8   9 1
            38    4  42 1 #Down
            39    9  21 1
            40    5  43 1 #Up
            41    9  10 1
            42    6  44 1 #Up
            43   21  22 1
            44    3  45 1 #Up
            45   10  11 1
            46   41  46 2
            47   22  23 1
            48   41  47 1
            49   11  12 1
            50   23  24 2

» Japanese version

DBGET integrated database retrieval system