Entry |
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Name |
Dexamethasone sodium phosphate
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Formula |
C22H28FO8P. 2Na
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Exact mass |
516.1301
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Mol weight |
516.40
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Structure |

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Remark |
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Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A01 STOMATOLOGICAL PREPARATIONS
A01A STOMATOLOGICAL PREPARATIONS
A01AC Corticosteroids for local oral treatment
A01AC02 Dexamethasone
D00975 Dexamethasone sodium phosphate (JAN/USP) <JP/US>
C CARDIOVASCULAR SYSTEM
C05 VASOPROTECTIVES
C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
C05AA Corticosteroids
C05AA09 Dexamethasone
D00975 Dexamethasone sodium phosphate (JAN/USP) <JP/US>
D DERMATOLOGICALS
D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D07A CORTICOSTEROIDS, PLAIN
D07AB Corticosteroids, moderately potent (group II)
D07AB19 Dexamethasone
D00975 Dexamethasone sodium phosphate (JAN/USP) <JP/US>
D07X CORTICOSTEROIDS, OTHER COMBINATIONS
D07XB Corticosteroids, moderately potent, other combinations
D07XB05 Dexamethasone
D00975 Dexamethasone sodium phosphate (JAN/USP) <JP/US>
D10 ANTI-ACNE PREPARATIONS
D10A ANTI-ACNE PREPARATIONS FOR TOPICAL USE
D10AA Corticosteroids, combinations for treatment of acne
D10AA03 Dexamethasone
D00975 Dexamethasone sodium phosphate (JAN/USP) <JP/US>
H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
H02 CORTICOSTEROIDS FOR SYSTEMIC USE
H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
H02AB Glucocorticoids
H02AB02 Dexamethasone
D00975 Dexamethasone sodium phosphate (JAN/USP) <JP/US>
R RESPIRATORY SYSTEM
R01 NASAL PREPARATIONS
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
R01AD Corticosteroids
R01AD03 Dexamethasone
D00975 Dexamethasone sodium phosphate (JAN/USP) <JP/US>
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01B ANTIINFLAMMATORY AGENTS
S01BA Corticosteroids, plain
S01BA01 Dexamethasone
D00975 Dexamethasone sodium phosphate (JAN/USP) <JP/US>
S01C ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION
S01CB Corticosteroids/antiinfectives/mydriatics in combination
S01CB01 Dexamethasone
D00975 Dexamethasone sodium phosphate (JAN/USP) <JP/US>
S02 OTOLOGICALS
S02B CORTICOSTEROIDS
S02BA Corticosteroids
S02BA06 Dexamethasone
D00975 Dexamethasone sodium phosphate (JAN/USP) <JP/US>
S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
S03B CORTICOSTEROIDS
S03BA Corticosteroids
S03BA01 Dexamethasone
D00975 Dexamethasone sodium phosphate (JAN/USP) <JP/US>
USP drug classification [BR:br08302]
Hormonal Agents, Stimulant/Replacement/Modifying (Adrenal)
Dexamethasone
D00975 Dexamethasone sodium phosphate (JAN/USP)
Inflammatory Bowel Disease Agents
Glucocorticoids
Dexamethasone
D00975 Dexamethasone sodium phosphate (JAN/USP)
Ophthalmic Agents
Ophthalmic Anti-inflammatories
Glucocorticoids, Ophthalmic
Dexamethasone
D00975 Dexamethasone sodium phosphate (JAN/USP)
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
13 Agents affecting sensory organs
131 Ophthalmic agents
1315 Ophthalmic cortisones
D00975 Dexamethasone sodium phosphate (JAN/USP)
132 Otic and nasal agents
1329 Others
D00975 Dexamethasone sodium phosphate (JAN/USP)
2 Agents affecting individual organs
24 Hormones
245 Adrenal hormone preparations
2454 Fluorinated adrenocorticotropic hormones
D00975 Dexamethasone sodium phosphate (JAN/USP)
Animal drugs in Japan [BR:br08331]
96 Agents affecting metabolism
961 Hormone preparations (except agents for breeding and external use)
9612 Adrenal hormone preparations
C08175 Dexamethasone sodium phosphate
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00011 Dexamethasone
D00975 Dexamethasone sodium phosphate
Dermatological agent
DG03243 Atopic dermatitis agent
D00975 Dexamethasone sodium phosphate
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG00011 Dexamethasone
D00975 Dexamethasone sodium phosphate
Metabolizing enzyme inducer
DG02853 CYP3A/CYP3A4 inducer
DG01635 CYP3A4 inducer
DG00011 Dexamethasone
D00975 Dexamethasone sodium phosphate
Drug classes [BR:br08332]
Anti-inflammatory
DG01955 Corticosteroid
D00975 Dexamethasone sodium phosphate
Dermatological agent
DG03243 Atopic dermatitis agent
D00975 Dexamethasone sodium phosphate
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C1 (GR)
D00975 Dexamethasone sodium phosphate (JAN/USP) <JP/US>
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00975
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Other DBs |
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LinkDB |
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KCF data |
ATOM 34
1 C1y C 20.5509 -18.6771
2 C1y C 19.3622 -19.3588
3 C1z C 20.5626 -17.2961
4 C1x C 22.9399 -18.7004
5 C1z C 18.1794 -18.6655
6 C1x C 19.3622 -20.7281
7 C1z C 21.7686 -16.6144
8 C1x C 19.3855 -16.6144
9 C1a C 20.5567 -15.9269
10 C1y C 22.9514 -17.3253
11 C1z C 16.9908 -19.3471
12 C1y C 18.1910 -17.2961
13 X F 18.1677 -20.0289
14 C1x C 18.1677 -21.4098
15 C5a C 21.7745 -15.2451
16 O1a O 23.0913 -16.2589
17 C1a C 24.2741 -17.2381
18 C2y C 16.9849 -20.7222
19 C2x C 15.8021 -18.6596
20 C1a C 16.9791 -17.9662
21 O1a O 17.0025 -16.6028
22 C1b C 22.9573 -14.5575
23 O5a O 20.5743 -14.5575
24 C2x C 15.8021 -21.4040
25 C2x C 14.6135 -19.3471
26 O2b O 24.1401 -15.2334
27 C5x C 14.6135 -20.7222
28 P1b P 25.2763 -14.4585
29 O5x O 13.4190 -21.3981
30 O1c O 26.4534 -15.1461
31 O1c O 26.4068 -13.6836 #-
32 O1c O 24.5014 -13.3223 #-
33 Z Na 28.9880 -14.9538 #+
34 Z Na 28.9181 -18.1935 #+
BOND 35
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 1
7 3 8 1
8 3 9 1 #Up
9 4 10 1
10 5 11 1
11 5 12 1
12 5 13 1 #Down
13 6 14 1
14 7 15 1 #Up
15 7 16 1 #Down
16 10 17 1 #Down
17 11 18 1
18 11 19 1
19 11 20 1 #Up
20 12 21 1 #Up
21 15 22 1
22 15 23 2
23 18 24 2
24 19 25 2
25 22 26 1
26 24 27 1
27 26 28 1
28 27 29 2
29 28 30 2
30 28 31 1
31 28 32 1
32 7 10 1
33 8 12 1
34 14 18 1
35 25 27 1
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