KEGG   DRUG: Methoxsalen
Entry
D00139                      Drug                                   
Name
Methoxsalen (JP18/USP);
Oxsoralen (TN);
UVADEX (TN)
Product
UVADEX (Therakos)
  Generic
METHOXSALEN (Strides Pharma Science Limited)
Formula
C12H8O4
Exact mass
216.0423
Mol weight
216.19
Structure
Simcomp
Class
Metabolizing enzyme inhibitor
 DG01525  CYP2A6 inhibitor
Remark
Same as: C01864
Therapeutic category: 2699
ATC code: D05AD02 D05BA02
Product: D00139<JP/US>
Efficacy
Antivitiligo, Pigmentation agent
  Disease
Psoriasis [DS:H01656]
Comment
Psoralen derivative
Interaction
CYP inhibition: CYP2A6 [HSA:1548]
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D05 ANTIPSORIATICS
   D05A ANTIPSORIATICS FOR TOPICAL USE
    D05AD Psoralens for topical use
     D05AD02 Methoxsalen
      D00139  Methoxsalen (JP18/USP) <JP/US>
   D05B ANTIPSORIATICS FOR SYSTEMIC USE
    D05BA Psoralens for systemic use
     D05BA02 Methoxsalen
      D00139  Methoxsalen (JP18/USP) <JP/US>
USP drug classification [BR:br08302]
 Dermatological Agents
  Dermatological Agents, Other
   Psoriasis Agents
    Methoxsalen
     D00139  Methoxsalen (JP18/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  26  Epidermides
   269  Miscellaneous
    2699  Others
     D00139  Methoxsalen (JP18/USP)
Drug groups [BR:br08330]
 Metabolizing enzyme inhibitor
  DG01525  CYP2A6 inhibitor
   D00139  Methoxsalen
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00139  Methoxsalen
Drug metabolizing enzymes and transporters [br08309.html]
 Drug metabolizing enzymes
  D00139
Other DBs
CAS: 298-81-7
PubChem: 7847207
ChEBI: 18358
PDB-CCD: 8MO[PDBj]
LigandBox: D00139
NIKKAJI: J2.983A
LinkDB
KCF data

ATOM        16
            1   C8y C    21.0700  -25.2700
            2   C8x C    21.0700  -26.6700
            3   C8x C    22.2824  -27.3700
            4   C8y C    23.4949  -26.6700
            5   C8y C    23.4949  -25.2700
            6   O7x O    22.2824  -24.5700
            7   C8x C    24.7073  -27.3700
            8   C8y C    25.9197  -26.6700
            9   C8y C    25.9197  -25.2700
            10  C8y C    24.7073  -24.5700
            11  C8x C    27.2512  -27.1026
            12  C8x C    28.0741  -25.9700
            13  O2x O    27.2512  -24.8374
            14  O6a O    19.8576  -24.5700
            15  O2a O    24.7073  -23.1700
            16  C1a C    25.9218  -22.4688
BOND        18
            1     1   2 1
            2     2   3 2
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     4   7 2
            8     7   8 1
            9     8   9 2
            10    9  10 1
            11    5  10 2
            12    8  11 1
            13   11  12 2
            14   12  13 1
            15    9  13 1
            16    1  14 2
            17   10  15 1
            18   15  16 1

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