Homo sapiens (human): 1548
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Entry
1548 CDS
T01001
Symbol
CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB
Name
(RefSeq) cytochrome P450 family 2 subfamily A member 6
KO
K17683
cytochrome P450 family 2 subfamily A6 [EC:1.14.14.-]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00232
Caffeine metabolism
hsa00830
Retinol metabolism
hsa00980
Metabolism of xenobiotics by cytochrome P450
hsa00982
Drug metabolism - cytochrome P450
hsa00983
Drug metabolism - other enzymes
hsa01100
Metabolic pathways
hsa05204
Chemical carcinogenesis - DNA adducts
hsa05417
Lipid and atherosclerosis
Network
nt06250
DNA adduct formation (cancer)
Element
N01379
NNK to DNA adducts
N01380
NNK to DNA adducts
N01381
NNK to DNA adducts
N01382
NNK to DNA adducts
Disease
H01205
Coumarin resistance
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00830 Retinol metabolism
1548 (CYP2A6)
09110 Biosynthesis of other secondary metabolites
00232 Caffeine metabolism
1548 (CYP2A6)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
1548 (CYP2A6)
00982 Drug metabolism - cytochrome P450
1548 (CYP2A6)
00983 Drug metabolism - other enzymes
1548 (CYP2A6)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
1548 (CYP2A6)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
1548 (CYP2A6)
09180 Brite Hierarchies
09181 Protein families: metabolism
00199 Cytochrome P450 [BR:
hsa00199
]
1548 (CYP2A6)
Cytochrome P450 [BR:
hsa00199
]
Cytochrome P450, animal type
CYP2 family
1548 (CYP2A6)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
p450
Motif
Other DBs
NCBI-GeneID:
1548
NCBI-ProteinID:
NP_000753
OMIM:
122720
HGNC:
2610
Ensembl:
ENSG00000255974
UniProt:
P11509
Structure
PDB
PDBj
LinkDB
All DBs
Position
19:complement(40843541..40850447)
Genome browser
AA seq
494 aa
AA seq
DB search
MLASGMLLVALLVCLTVMVLMSVWQQRKSKGKLPPGPTPLPFIGNYLQLNTEQMYNSLMK
ISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSN
GERAKQLRRFSIATLRDFGVGKRGIEERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSN
VISSIVFGDRFDYKDKEFLSLLRMMLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFQL
LQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQEEEKNPNTEFYLKNLVMTTLNLFI
GGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYMEAVIHEIQ
RFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEK
GQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQSPKDIDVSPKHVGF
ATIPRNYTMSFLPR
NT seq
1485 nt
NT seq
+upstream
nt +downstream
nt
atgctggcctcagggatgcttctggtggccttgctggtctgcctgactgtaatggtcttg
atgtctgtttggcagcagaggaagagcaaggggaagctgcctccgggacccaccccattg
cccttcattggaaactacctgcagctgaacacagagcagatgtacaactccctcatgaag
atcagtgagcgctatggccccgtgttcaccattcacttggggccccggcgggtcgtggtg
ctgtgtggacatgatgccgtcagggaggctctggtggaccaggctgaggagttcagcggg
cgaggcgagcaagccaccttcgactgggtcttcaaaggctatggcgtggtattcagcaac
ggggagcgcgccaagcagctccggcgcttctccatcgccaccctgcgggacttcggggtg
ggcaagcgaggcatcgaggagcgcatccaggaggaggcgggcttcctcatcgacgccctc
cggggcactggcggcgccaatatcgatcccaccttcttcctgagccgcacagtctccaat
gtcatcagctccattgtctttggggaccgctttgactataaggacaaagagttcctgtca
ctgttgcgcatgatgctaggaatcttccagttcacgtcaacctccacggggcagctctat
gagatgttctcttcggtgatgaaacacctgccaggaccacagcaacaggcctttcagttg
ctgcaagggctggaggacttcatagccaagaaggtggagcacaaccagcgcacgctggat
cccaattccccacgggacttcattgactcctttctcatccgcatgcaggaggaggagaag
aaccccaacacggagttctacttgaaaaacctggtgatgaccacgttgaacctcttcatt
gggggcaccgagaccgtcagcaccaccctgcgctatggcttcttgctgctcatgaagcac
ccagaggtggaggccaaggtccatgaggagattgacagagtgatcggcaagaaccggcag
cccaagtttgaggaccgggccaagatgccctacatggaggcagtgatccacgagatccaa
agatttggagacgtgatccccatgagtttggcccgcagagtcaaaaaggacaccaagttt
cgggatttcttcctccctaagggcaccgaagtgtaccctatgctgggctctgtgctgaga
gaccccagtttcttctccaacccccaggacttcaatccccagcacttcctgaatgagaag
gggcagtttaagaagagtgatgcttttgtgcccttttccatcggaaagcggaactgtttc
ggagaaggcctggccagaatggagctctttctcttcttcaccaccgtcatgcagaacttc
cgcctcaagtcctcccagtcacctaaggacattgacgtgtcccccaaacacgtgggcttt
gccacgatcccacgaaactacaccatgagcttcctgccccgctga
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