| Entry |
|
|---|
| Name |
Chlorambucil (JAN/USP/INN);
Leukeran (TN) |
|---|
| Product |
|
|---|
| Formula |
C14H19Cl2NO2
|
|---|
| Exact mass |
303.0793
|
|---|
| Mol weight |
304.21
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antineoplastic
DG01677 Alkylating agent
DG01678 Nitrogen mustard analog
|
|---|
| Remark |
|
|---|
| Efficacy |
Antineoplastic, Alkylating agent |
|---|
| Disease |
Chronic lymphatic (lymphocytic) leukemia [DS: H00005] Giant follicular lymphoma [DS: H01613] Hodgkin's disease [DS: H00007] |
|---|
| Target |
DNA |
|---|
| Interaction |
|
|---|
| Structure map |
| map07040 | Antineoplastics - alkylating agents |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L01 ANTINEOPLASTIC AGENTS
L01A ALKYLATING AGENTS
L01AA Nitrogen mustard analogues
L01AA02 Chlorambucil
D00266 Chlorambucil (JAN/USP/INN) <US>
USP drug classification [BR:br08302]
Antineoplastics
Alkylating Agents
Nitrogen Mustards
Chlorambucil
D00266 Chlorambucil (JAN/USP/INN)
Drug groups [BR:br08330]
Antineoplastic
DG01677 Alkylating agent
DG01678 Nitrogen mustard analog
D00266 Chlorambucil
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 19
1 C8y C 31.9900 -18.6900
2 N1c N 33.1800 -19.3900
3 C8x C 31.9900 -17.2900
4 C8x C 30.7300 -19.3900
5 C1b C 34.3700 -18.6900
6 C1b C 33.1800 -20.7900
7 C8x C 30.7300 -16.5900
8 C8x C 29.5400 -18.6900
9 C1b C 34.3700 -17.2900
10 C1b C 31.9900 -21.4900
11 C8y C 29.5400 -17.2900
12 X Cl 35.6300 -16.5900
13 X Cl 31.9900 -22.8900
14 C1b C 28.3500 -16.5900
15 C1b C 27.0900 -17.2900
16 C1b C 25.9000 -16.5900
17 C6a C 24.7100 -17.2900
18 O6a O 23.4500 -16.5900
19 O6a O 24.7100 -18.6900
BOND 19
1 1 2 1
2 1 3 2
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 1
7 4 8 2
8 5 9 1
9 6 10 1
10 7 11 2
11 9 12 1
12 10 13 1
13 11 14 1
14 14 15 1
15 15 16 1
16 16 17 1
17 17 18 1
18 17 19 2
19 8 11 1
|
|---|
