KEGG   DRUG: ChlorambucilHelp
Entry
D00266                      Drug                                   

Name
Chlorambucil (JAN/USP/INN);
Leukeran (TN)
Product
Formula
C14H19Cl2NO2
Exact mass
303.0793
Mol weight
304.2122
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Antineoplastic
 DG01677  Alkylating agent
  DG01678  Nitrogen mustard analog
Remark
Same as: C06900
ATC code: L01AA02
Product: D00266<US>
Efficacy
Antineoplastic, Alkylating agent
  Disease
Chronic lymphatic (lymphocytic) leukemia [DS:H00005]
Giant follicular lymphoma [DS:H01613]
Hodgkin's disease [DS:H00007]
Target
DNA
Interaction
Drug interaction
Structure map
map07040  Antineoplastics - alkylating agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L01 ANTINEOPLASTIC AGENTS
   L01A ALKYLATING AGENTS
    L01AA Nitrogen mustard analogues
     L01AA02 Chlorambucil
      D00266  Chlorambucil (JAN/USP/INN) <US>
USP drug classification [BR:br08302]
 Antineoplastics
  Alkylating Agents
   Chlorambucil
    D00266  Chlorambucil (JAN/USP/INN)
Antineoplastics [br08340.html]
 D00266
BRITE hierarchy
Other DBs
CAS: 305-03-3
PubChem: 7847332
ChEBI: 28830
ChEMBL: CHEMBL515
DrugBank: DB00291
PDB-CCD: CBL[PDBj]
LigandBox: D00266
NIKKAJI: J1.521K
LinkDB All DBs
KCF data Show

ATOM        19
            1   C8y C    31.9900  -18.6900
            2   N1c N    33.1800  -19.3900
            3   C8x C    31.9900  -17.2900
            4   C8x C    30.7300  -19.3900
            5   C1b C    34.3700  -18.6900
            6   C1b C    33.1800  -20.7900
            7   C8x C    30.7300  -16.5900
            8   C8x C    29.5400  -18.6900
            9   C1b C    34.3700  -17.2900
            10  C1b C    31.9900  -21.4900
            11  C8y C    29.5400  -17.2900
            12  X   Cl   35.6300  -16.5900
            13  X   Cl   31.9900  -22.8900
            14  C1b C    28.3500  -16.5900
            15  C1b C    27.0900  -17.2900
            16  C1b C    25.9000  -16.5900
            17  C6a C    24.7100  -17.2900
            18  O6a O    23.4500  -16.5900
            19  O6a O    24.7100  -18.6900
BOND        19
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     4   8 2
            8     5   9 1
            9     6  10 1
            10    7  11 2
            11    9  12 1
            12   10  13 1
            13   11  14 1
            14   14  15 1
            15   15  16 1
            16   16  17 1
            17   17  18 1
            18   17  19 2
            19    8  11 1

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