| Entry |
|
|---|
| Name |
Prochlorperazine (JAN/USP/INN);
Compro (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C20H24ClN3S
|
|---|
| Exact mass |
373.1379
|
|---|
| Mol weight |
373.94
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG03200 Antipsychotic agent
DG01905 Phenothiazine antipsychotics
|
|---|
| Remark |
| Product (DG00876): | D00493<US> D00479<JP/US> D02022<JP> D02609<US> |
|
|---|
| Efficacy |
Antipsychotic, Anti-emetic, Dopamine D2 receptor antagonist |
|---|
| Comment |
Phenothiazine derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07029 | Antipsychotics - phenothiazines |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05A ANTIPSYCHOTICS
N05AB Phenothiazines with piperazine structure
N05AB04 Prochlorperazine
D00493 Prochlorperazine (JAN/USP/INN) <US>
USP drug classification [BR:br08302]
Antiemetics
Antiemetics, Other
Prochlorperazine
D00493 Prochlorperazine (JAN/USP/INN)
Antipsychotics
1st Generation/Typical
Prochlorperazine
D00493 Prochlorperazine (JAN/USP/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00876 Prochlorperazine
D00493 Prochlorperazine
DG03200 Antipsychotic agent
DG01905 Phenothiazine antipsychotics
DG00876 Prochlorperazine
D00493 Prochlorperazine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD2
D00493 Prochlorperazine (JAN/USP/INN) <US>
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00876 Prochlorperazine
DG03200 Antipsychotic agent
DG01905 Phenothiazine antipsychotics
DG00876 Prochlorperazine
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 25
1 C8x C 9.8700 -14.4200
2 C8x C 9.8700 -15.8200
3 C8x C 11.0824 -16.5200
4 C8y C 12.2949 -15.8200
5 C8y C 12.2949 -14.4200
6 C8x C 11.0824 -13.7200
7 S2x S 13.5073 -16.5200
8 C8y C 14.7197 -15.8200
9 C8y C 14.7197 -14.4200
10 N4y N 13.5073 -13.7200
11 C8x C 15.9322 -16.5200
12 C8x C 17.1446 -15.8200
13 C8y C 17.1446 -14.4200
14 C8x C 15.9322 -13.7200
15 C1b C 13.5073 -12.3200
16 X Cl 18.3611 -13.7177
17 C1b C 14.7218 -11.6188
18 C1b C 15.9183 -12.3098
19 N1y N 17.1051 -11.6246
20 C1x C 18.2966 -12.3128
21 C1x C 19.5091 -11.6129
22 N1y N 19.5093 -10.2129
23 C1x C 18.3178 -9.5248
24 C1x C 17.1053 -10.2246
25 C1a C 20.7341 -9.5058
BOND 28
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 8 11 2
13 11 12 1
14 12 13 2
15 13 14 1
16 9 14 2
17 10 15 1
18 13 16 1
19 15 17 1
20 17 18 1
21 18 19 1
22 19 20 1
23 20 21 1
24 21 22 1
25 22 23 1
26 23 24 1
27 19 24 1
28 22 25 1
|
|---|
